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  5. evm.model.contig_2185.5

evm.model.contig_2185.5


Description : (at3g48190 : 373.0) encodes a homolog of the human ATM gene, which is mutated in ataxia telangiectasia, a chromosome instability disorder. Characterization of mutants suggest a role in repairing DNA in response to ionizing radiation as well as during meiosis. The protein has kinase domains and shows kinase activity in orthologs. There is also evidence that ATM might be involved in the telomerase-independent process known as Alternative Lengthening of Telomeres.; ataxia-telangiectasia mutated (ATM); FUNCTIONS IN: 1-phosphatidylinositol-3-phosphate 5-kinase activity; INVOLVED IN: in 8 processes; LOCATED IN: chloroplast; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Phosphatidylinositol 3-/4-kinase, catalytic (InterPro:IPR000403), PIK-related kinase, FAT (InterPro:IPR003151), Ataxia-Telangiectasia Mutated (InterPro:IPR015519), PIK-related kinase (InterPro:IPR014009), PWWP (InterPro:IPR000313), PIK-related kinase, FATC (InterPro:IPR003152), Phosphatidylinositol 3/4-kinase, conserved site (InterPro:IPR018936), Protein kinase-like domain (InterPro:IPR011009); BEST Arabidopsis thaliana protein match is: Ataxia telangiectasia-mutated and RAD3-related (TAIR:AT5G40820.1); Has 3479 Blast hits to 3364 proteins in 268 species: Archae - 0; Bacteria - 7; Metazoa - 1400; Fungi - 858; Plants - 531; Viruses - 0; Other Eukaryotes - 683 (source: NCBI BLink). & (q5z987|atr_orysa : 206.0) Serine/threonine-protein kinase ATR (EC 2.7.11.1) - Oryza sativa (Rice) & (gnl|cdd|68872 : 165.0) no description available & (gnl|cdd|39774 : 84.8) no description available & (reliability: 746.0) & (original description: no original description)


Gene families : OG_42_0006876 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0006876_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Porphyridium release: evm.model.contig_2185.5
Cluster HCCA clusters: Cluster_27

Target Alias Description ECC score Gene Family Method Actions
Glyma.04G182900 No alias ataxia-telangiectasia mutated 0.02 Orthogroups_2024-Update
HORVU3Hr1G000420.22 No alias DNA double-strand break transducer kinase *(ATM) 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0004175 endopeptidase activity IEP Predicted GO
MF GO:0004222 metalloendopeptidase activity IEP Predicted GO
MF GO:0005244 voltage-gated ion channel activity IEP Predicted GO
MF GO:0005247 voltage-gated chloride channel activity IEP Predicted GO
MF GO:0005253 anion channel activity IEP Predicted GO
MF GO:0005254 chloride channel activity IEP Predicted GO
BP GO:0005992 trehalose biosynthetic process IEP Predicted GO
BP GO:0006508 proteolysis IEP Predicted GO
BP GO:0006821 chloride transport IEP Predicted GO
BP GO:0007155 cell adhesion IEP Predicted GO
MF GO:0008233 peptidase activity IEP Predicted GO
MF GO:0008234 cysteine-type peptidase activity IEP Predicted GO
MF GO:0008237 metallopeptidase activity IEP Predicted GO
MF GO:0008308 voltage-gated anion channel activity IEP Predicted GO
MF GO:0015108 chloride transmembrane transporter activity IEP Predicted GO
BP GO:0016579 protein deubiquitination IEP Predicted GO
MF GO:0019783 ubiquitin-like protein-specific protease activity IEP Predicted GO
BP GO:0022610 biological adhesion IEP Predicted GO
MF GO:0022832 voltage-gated channel activity IEP Predicted GO
MF GO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEP Predicted GO
BP GO:0046351 disaccharide biosynthetic process IEP Predicted GO
MF GO:0070011 peptidase activity, acting on L-amino acid peptides IEP Predicted GO
BP GO:0070646 protein modification by small protein removal IEP Predicted GO
BP GO:0070647 protein modification by small protein conjugation or removal IEP Predicted GO
MF GO:0101005 ubiquitinyl hydrolase activity IEP Predicted GO
InterPro domains Description Start Stop
IPR003152 FATC_dom 4386 4415
IPR000403 PI3/4_kinase_cat_dom 4072 4319
No external refs found!