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  5. evm.model.contig_2242.1

evm.model.contig_2242.1


Description : (at1g63440 : 202.0) The Arabidopsis P-type ATPase HMA5 is involved in Cu detoxification. hma5 mutant plants exhibit Cu hypersensitivity, which is especially dramatic in roots where HMA5 is mostly expressed.; heavy metal atpase 5 (HMA5); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; INVOLVED IN: detoxification of copper ion, response to copper ion; LOCATED IN: integral to membrane, membrane; EXPRESSED IN: 8 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Heavy metal transport/detoxification protein (InterPro:IPR006121), ATPase, P type, cation/copper-transporter (InterPro:IPR006403), ATPase, P-type, ATPase-associated domain (InterPro:IPR008250), Heavy-metal-associated, conserved site (InterPro:IPR017969), Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (InterPro:IPR001757), ATPase, P-type, heavy metal translocating (InterPro:IPR006416), ATPase, P-type phosphorylation site (InterPro:IPR018303); BEST Arabidopsis thaliana protein match is: copper-exporting ATPase / responsive-to-antagonist 1 / copper-transporting ATPase (RAN1) (TAIR:AT5G44790.1); Has 47061 Blast hits to 34034 proteins in 3459 species: Archae - 1020; Bacteria - 31793; Metazoa - 4958; Fungi - 2589; Plants - 1873; Viruses - 3; Other Eukaryotes - 4825 (source: NCBI BLink). & (reliability: 404.0) & (original description: no original description)


Gene families : OG_42_0000805 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000805_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Porphyridium release: evm.model.contig_2242.1
Cluster HCCA clusters: Cluster_3

Target Alias Description ECC score Gene Family Method Actions
A4A49_16235 No alias putative copper-transporting atpase hma5 0.01 Orthogroups_2024-Update
A4A49_34854 No alias copper-transporting atpase ran1 0.02 Orthogroups_2024-Update
Brara.F03711.1 No alias P1B-type heavy metal cation-transporting ATPase *(HMA) 0.02 Orthogroups_2024-Update
Glyma.03G086000 No alias heavy metal atpase 5 0.02 Orthogroups_2024-Update
HORVU6Hr1G031970.2 No alias P1B-type heavy metal cation-transporting ATPase *(HMA) 0.01 Orthogroups_2024-Update
Mp3g13400.1 No alias P1B-type heavy metal cation-transporting ATPase (HMA) 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source
BP GO:0030001 metal ion transport IEA InterProScan predictions
MF GO:0046872 metal ion binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
BP GO:0000041 transition metal ion transport IEP Predicted GO
MF GO:0000166 nucleotide binding IEP Predicted GO
MF GO:0003824 catalytic activity IEP Predicted GO
MF GO:0004345 glucose-6-phosphate dehydrogenase activity IEP Predicted GO
MF GO:0004347 glucose-6-phosphate isomerase activity IEP Predicted GO
MF GO:0004672 protein kinase activity IEP Predicted GO
MF GO:0005375 copper ion transmembrane transporter activity IEP Predicted GO
MF GO:0005509 calcium ion binding IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
BP GO:0005975 carbohydrate metabolic process IEP Predicted GO
BP GO:0005996 monosaccharide metabolic process IEP Predicted GO
BP GO:0006006 glucose metabolic process IEP Predicted GO
BP GO:0006094 gluconeogenesis IEP Predicted GO
BP GO:0006163 purine nucleotide metabolic process IEP Predicted GO
BP GO:0006464 cellular protein modification process IEP Predicted GO
BP GO:0006468 protein phosphorylation IEP Predicted GO
BP GO:0006793 phosphorus metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
BP GO:0006807 nitrogen compound metabolic process IEP Predicted GO
BP GO:0006825 copper ion transport IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
BP GO:0008152 metabolic process IEP Predicted GO
BP GO:0009123 nucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009126 purine nucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009141 nucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009144 purine nucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009150 purine ribonucleotide metabolic process IEP Predicted GO
BP GO:0009161 ribonucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009167 purine ribonucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009199 ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009205 purine ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009259 ribonucleotide metabolic process IEP Predicted GO
MF GO:0016209 antioxidant activity IEP Predicted GO
MF GO:0016301 kinase activity IEP Predicted GO
BP GO:0016310 phosphorylation IEP Predicted GO
MF GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016772 transferase activity, transferring phosphorus-containing groups IEP Predicted GO
MF GO:0016773 phosphotransferase activity, alcohol group as acceptor IEP Predicted GO
MF GO:0016853 isomerase activity IEP Predicted GO
BP GO:0017144 drug metabolic process IEP Predicted GO
BP GO:0019318 hexose metabolic process IEP Predicted GO
BP GO:0019319 hexose biosynthetic process IEP Predicted GO
BP GO:0019538 protein metabolic process IEP Predicted GO
BP GO:0019693 ribose phosphate metabolic process IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
BP GO:0034220 ion transmembrane transport IEP Predicted GO
BP GO:0035434 copper ion transmembrane transport IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
BP GO:0036211 protein modification process IEP Predicted GO
BP GO:0043412 macromolecule modification IEP Predicted GO
BP GO:0044238 primary metabolic process IEP Predicted GO
BP GO:0044260 cellular macromolecule metabolic process IEP Predicted GO
BP GO:0044267 cellular protein metabolic process IEP Predicted GO
BP GO:0044281 small molecule metabolic process IEP Predicted GO
BP GO:0046034 ATP metabolic process IEP Predicted GO
BP GO:0046364 monosaccharide biosynthetic process IEP Predicted GO
MF GO:0046915 transition metal ion transmembrane transporter activity IEP Predicted GO
MF GO:0051920 peroxiredoxin activity IEP Predicted GO
BP GO:0055114 oxidation-reduction process IEP Predicted GO
BP GO:0071704 organic substance metabolic process IEP Predicted GO
BP GO:0072521 purine-containing compound metabolic process IEP Predicted GO
BP GO:0098655 cation transmembrane transport IEP Predicted GO
BP GO:0098660 inorganic ion transmembrane transport IEP Predicted GO
BP GO:0098662 inorganic cation transmembrane transport IEP Predicted GO
MF GO:0140096 catalytic activity, acting on a protein IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
BP GO:1901564 organonitrogen compound metabolic process IEP Predicted GO
InterPro domains Description Start Stop
IPR006121 HMA_dom 78 138
IPR006121 HMA_dom 158 216
No external refs found!