evm.model.contig_3396.7

Description : (at2g34660 : 863.0) encodes a multidrug resistance-associated protein that is MgATP-energized glutathione S-conjugate pump. The expression of this gene is upregulated by herbicide safeners such as benoxacor and fenclorim.; multidrug resistance-associated protein 2 (MRP2); CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: multidrug resistance-associated protein 1 (TAIR:AT1G30400.2). & (q6yuu5|mdr_orysa : 246.0) Putative multidrug resistance protein (P-glycoprotein) - Oryza sativa (Rice) & (reliability: 1726.0) & (original description: no original description)

Gene families : OG_42_0000076 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000076_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Porphyridium release: evm.model.contig_3396.7
Cluster	HCCA clusters: Cluster_66

Target	Alias	Description	ECC score	Gene Family Method
171469	No alias	multidrug resistance-associated protein 6	0.02	Orthogroups_2024-Update
409191	No alias	multidrug resistance-associated protein 6	0.02	Orthogroups_2024-Update
Bradi2g04577	No alias	multidrug resistance-associated protein 3	0.01	Orthogroups_2024-Update
Brara.E00958.1	No alias	glutathione S-conjugate transporter & subfamily ABCC transporter	0.02	Orthogroups_2024-Update
Brara.E02088.1	No alias	subfamily ABCC transporter	0.02	Orthogroups_2024-Update
Brara.J00233.1	No alias	subfamily ABCC transporter	0.02	Orthogroups_2024-Update
Cre17.g734612	No alias	multidrug resistance-associated protein 2	0.01	Orthogroups_2024-Update
GRMZM2G365957	No alias	multidrug resistance-associated protein 4	0.02	Orthogroups_2024-Update
Glyma.08G101500	No alias	multidrug resistance-associated protein 3	0.01	Orthogroups_2024-Update
Glyma.08G194700	No alias	multidrug resistance-associated protein 6	0.02	Orthogroups_2024-Update
Glyma.10G019000	No alias	multidrug resistance-associated protein 4	0.01	Orthogroups_2024-Update
Glyma.13G220000	No alias	multidrug resistance-associated protein 2	0.01	Orthogroups_2024-Update
MA_8849g0010	No alias	(at3g13080 : 1497.0) encodes an ATP-dependent MRP-like...	0.02	Orthogroups_2024-Update
Mp4g11950.1	No alias	subfamily ABCC transporter	0.01	Orthogroups_2024-Update
PSME_00011253-RA	No alias	(at1g04120 : 384.0) encodes a high-affinity inositol...	0.01	Orthogroups_2024-Update
PSME_00019176-RA	No alias	(at3g13080 : 209.0) encodes an ATP-dependent MRP-like...	0.01	Orthogroups_2024-Update
Potri.003G182601	No alias	multidrug resistance-associated protein 11	0.02	Orthogroups_2024-Update
Pp1s223_76V6	No alias	multidrug resistance protein abc transporter family	0.02	Orthogroups_2024-Update
Pp1s540_4V6	No alias	multidrug resistance protein abc transporter family	0.01	Orthogroups_2024-Update
Seita.3G111900.1	No alias	subfamily ABCC transporter	0.01	Orthogroups_2024-Update
Seita.5G163300.1	No alias	subfamily ABCC transporter	0.02	Orthogroups_2024-Update
Seita.7G043600.1	No alias	subfamily ABCC transporter	0.01	Orthogroups_2024-Update
evm.model.tig00000718.1	No alias	(at2g34660 : 358.0) encodes a multidrug...	0.03	Orthogroups_2024-Update
evm.model.tig00000718.2	No alias	(at2g34660 : 171.0) encodes a multidrug...	0.01	Orthogroups_2024-Update
evm.model.tig00000718.3	No alias	(at3g13090 : 182.0) member of MRP subfamily; multidrug...	0.01	Orthogroups_2024-Update
evm.model.tig00001254.7	No alias	(at2g47800 : 162.0) Encodes a plasma membrane localized...	0.01	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005215	transporter activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
MF	GO:0015399	primary active transmembrane transporter activity	None	Extended
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	None	Extended
CC	GO:0016021	integral component of membrane	IEA	InterProScan predictions
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	IEA	InterProScan predictions
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0022804	active transmembrane transporter activity	None	Extended
MF	GO:0022857	transmembrane transporter activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IEA	InterProScan predictions
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0043492	ATPase activity, coupled to movement of substances	None	Extended
CC	GO:0044425	membrane part	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0055085	transmembrane transport	IEA	InterProScan predictions
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000030	mannosyltransferase activity	IEP	Predicted GO
MF	GO:0004357	glutamate-cysteine ligase activity	IEP	Predicted GO
MF	GO:0004402	histone acetyltransferase activity	IEP	Predicted GO
BP	GO:0006473	protein acetylation	IEP	Predicted GO
BP	GO:0006475	internal protein amino acid acetylation	IEP	Predicted GO
BP	GO:0006694	steroid biosynthetic process	IEP	Predicted GO
BP	GO:0006749	glutathione metabolic process	IEP	Predicted GO
BP	GO:0006750	glutathione biosynthetic process	IEP	Predicted GO
MF	GO:0008080	N-acetyltransferase activity	IEP	Predicted GO
MF	GO:0008452	RNA ligase activity	IEP	Predicted GO
MF	GO:0016410	N-acyltransferase activity	IEP	Predicted GO
BP	GO:0016573	histone acetylation	IEP	Predicted GO
MF	GO:0016881	acid-amino acid ligase activity	IEP	Predicted GO
BP	GO:0018205	peptidyl-lysine modification	IEP	Predicted GO
BP	GO:0018393	internal peptidyl-lysine acetylation	IEP	Predicted GO
BP	GO:0018394	peptidyl-lysine acetylation	IEP	Predicted GO
BP	GO:0019184	nonribosomal peptide biosynthetic process	IEP	Predicted GO
MF	GO:0022890	inorganic cation transmembrane transporter activity	IEP	Predicted GO
CC	GO:0030176	integral component of endoplasmic reticulum membrane	IEP	Predicted GO
CC	GO:0031227	intrinsic component of endoplasmic reticulum membrane	IEP	Predicted GO
CC	GO:0033179	proton-transporting V-type ATPase, V0 domain	IEP	Predicted GO
MF	GO:0034212	peptide N-acetyltransferase activity	IEP	Predicted GO
BP	GO:0043543	protein acylation	IEP	Predicted GO
MF	GO:0061733	peptide-lysine-N-acetyltransferase activity	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR003439	ABC_transporter-like	593	727
IPR003439	ABC_transporter-like	1225	1373
IPR011527	ABC1_TM_dom	889	1141
IPR011527	ABC1_TM_dom	203	469

External Links

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evm.model.contig_3396.7

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation