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  5. evm.model.contig_3407.7

evm.model.contig_3407.7


Description : (at1g23260 : 184.0) MMZ1/UEV1A encodes a protein that may play a role in DNA damage responses and error-free post-replicative DNA repair by participating in lysine-63-based polyubiquitination reactions. UEV1A can form diubiquitin and triubiquitin chains in combination with UBC13A/UBC35 in vitro. It can also functionally complement an mms2 mutation in budding yeast, both by increasing mms2 mutant viability in the presence of the DNA damaging agent MMS, and by reducing the rate of spontaneous DNA mutation. However, a combination of MMZ1/UEV1A and UBC13A do not do a good job of rescuing an mms2 ubc13 double mutant in yeast. MMZ1/UEV1A transcripts are found at low levels in most plant organs, but cannot be detected in the pollen. Transcript levels do not appear to be stress-inducible. The uev1a-1 mutant shows normal sensitivity to MMS in germination assays suggesting that UEV1A is not required for DNA damage tolerance during this developmental stage.; MMS ZWEI homologue 1 (MMZ1); CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608); BEST Arabidopsis thaliana protein match is: MMS ZWEI homologue 2 (TAIR:AT1G70660.1); Has 4438 Blast hits to 4438 proteins in 315 species: Archae - 0; Bacteria - 0; Metazoa - 2178; Fungi - 730; Plants - 896; Viruses - 0; Other Eukaryotes - 634 (source: NCBI BLink). & (reliability: 356.0) & (original description: no original description)


Gene families : OG_42_0001236 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001236_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Porphyridium release: evm.model.contig_3407.7
Cluster HCCA clusters: Cluster_38

Target Alias Description ECC score Gene Family Method Actions
Potri.016G073100 No alias ubiquitin E2 variant 1D-4 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source
BP GO:0000075 cell cycle checkpoint IEP Predicted GO
BP GO:0000959 mitochondrial RNA metabolic process IEP Predicted GO
MF GO:0005543 phospholipid binding IEP Predicted GO
CC GO:0005643 nuclear pore IEP Predicted GO
CC GO:0005739 mitochondrion IEP Predicted GO
BP GO:0007088 regulation of mitotic nuclear division IEP Predicted GO
BP GO:0007093 mitotic cell cycle checkpoint IEP Predicted GO
BP GO:0007094 mitotic spindle assembly checkpoint IEP Predicted GO
BP GO:0007346 regulation of mitotic cell cycle IEP Predicted GO
MF GO:0008146 sulfotransferase activity IEP Predicted GO
MF GO:0008289 lipid binding IEP Predicted GO
BP GO:0010564 regulation of cell cycle process IEP Predicted GO
BP GO:0010639 negative regulation of organelle organization IEP Predicted GO
BP GO:0010948 negative regulation of cell cycle process IEP Predicted GO
BP GO:0010965 regulation of mitotic sister chromatid separation IEP Predicted GO
BP GO:0016197 endosomal transport IEP Predicted GO
BP GO:0016482 cytosolic transport IEP Predicted GO
MF GO:0016782 transferase activity, transferring sulfur-containing groups IEP Predicted GO
MF GO:0017056 structural constituent of nuclear pore IEP Predicted GO
BP GO:0022402 cell cycle process IEP Predicted GO
BP GO:0030071 regulation of mitotic metaphase/anaphase transition IEP Predicted GO
BP GO:0031577 spindle checkpoint IEP Predicted GO
BP GO:0033043 regulation of organelle organization IEP Predicted GO
BP GO:0033044 regulation of chromosome organization IEP Predicted GO
BP GO:0033045 regulation of sister chromatid segregation IEP Predicted GO
BP GO:0033046 negative regulation of sister chromatid segregation IEP Predicted GO
BP GO:0033047 regulation of mitotic sister chromatid segregation IEP Predicted GO
BP GO:0033048 negative regulation of mitotic sister chromatid segregation IEP Predicted GO
BP GO:0042147 retrograde transport, endosome to Golgi IEP Predicted GO
CC GO:0044428 nuclear part IEP Predicted GO
BP GO:0045786 negative regulation of cell cycle IEP Predicted GO
BP GO:0045839 negative regulation of mitotic nuclear division IEP Predicted GO
BP GO:0045841 negative regulation of mitotic metaphase/anaphase transition IEP Predicted GO
BP GO:0045930 negative regulation of mitotic cell cycle IEP Predicted GO
MF GO:0051087 chaperone binding IEP Predicted GO
BP GO:0051128 regulation of cellular component organization IEP Predicted GO
BP GO:0051129 negative regulation of cellular component organization IEP Predicted GO
BP GO:0051783 regulation of nuclear division IEP Predicted GO
BP GO:0051784 negative regulation of nuclear division IEP Predicted GO
BP GO:0051983 regulation of chromosome segregation IEP Predicted GO
BP GO:0051985 negative regulation of chromosome segregation IEP Predicted GO
BP GO:0071173 spindle assembly checkpoint IEP Predicted GO
BP GO:0071174 mitotic spindle checkpoint IEP Predicted GO
BP GO:1901987 regulation of cell cycle phase transition IEP Predicted GO
BP GO:1901988 negative regulation of cell cycle phase transition IEP Predicted GO
BP GO:1901990 regulation of mitotic cell cycle phase transition IEP Predicted GO
BP GO:1901991 negative regulation of mitotic cell cycle phase transition IEP Predicted GO
BP GO:1902099 regulation of metaphase/anaphase transition of cell cycle IEP Predicted GO
BP GO:1902100 negative regulation of metaphase/anaphase transition of cell cycle IEP Predicted GO
BP GO:1903047 mitotic cell cycle process IEP Predicted GO
BP GO:1905818 regulation of chromosome separation IEP Predicted GO
BP GO:1905819 negative regulation of chromosome separation IEP Predicted GO
BP GO:2000816 negative regulation of mitotic sister chromatid separation IEP Predicted GO
BP GO:2001251 negative regulation of chromosome organization IEP Predicted GO
InterPro domains Description Start Stop
IPR000608 UBQ-conjugat_E2 37 131
No external refs found!