Description : (at5g41360 : 736.0) Encodes XPB2, a DNA repair protein and transcription factor. Arabidopsis thaliana has duplicated XPB gene (AtXPB1 and AtXPB2, with high similarity to each other). XPB proteins are involved in both DNA repair and transcription, they are component of the transcription factor IIH (TFIIH) and are responsible for DNA helicase activity during nucleotide (nt) excision repair (NER). Complementation assays in yeast rad25 mutant strains suggest the involvement of AtXPB2 in DNA repair. Although both genes are expressed in a constitutive manner during the plant life cycle, Northern blot analyses suggest that light modulates the expression level of both XPB copies.; homolog of Xeroderma pigmentosum complementation group B 2 (XPB2); FUNCTIONS IN: in 7 functions; INVOLVED IN: response to UV-B, N-terminal protein myristoylation; EXPRESSED IN: whole plant; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: Restriction endonuclease, type I, R subunit/Type III, Res subunit (InterPro:IPR006935), DEAD-like helicase, N-terminal (InterPro:IPR014001), Xeroderma pigmentosum group B protein (XP-B) (InterPro:IPR001161), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: homolog of xeroderma pigmentosum complementation group B 1 (TAIR:AT5G41370.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 1472.0) & (original description: no original description)
Gene families : OG_42_0003616 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003616_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Porphyridium release: evm.model.contig_3597.6 | |
Cluster | HCCA clusters: Cluster_26 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
PSME_00044237-RA | No alias | (at5g41360 : 583.0) Encodes XPB2, a DNA repair protein... | 0.01 | Orthogroups_2024-Update | |
Sopen08g029660 | No alias | Helicase conserved C-terminal domain | 0.03 | Orthogroups_2024-Update | |
evm.model.tig00000949.17 | No alias | (at5g41360 : 573.0) Encodes XPB2, a DNA repair protein... | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003677 | DNA binding | IEA | InterProScan predictions |
MF | GO:0005524 | ATP binding | IEA | InterProScan predictions |
MF | GO:0016787 | hydrolase activity | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
CC | GO:0000159 | protein phosphatase type 2A complex | IEP | Predicted GO |
BP | GO:0000726 | non-recombinational repair | IEP | Predicted GO |
MF | GO:0004518 | nuclease activity | IEP | Predicted GO |
MF | GO:0004672 | protein kinase activity | IEP | Predicted GO |
BP | GO:0006281 | DNA repair | IEP | Predicted GO |
BP | GO:0006302 | double-strand break repair | IEP | Predicted GO |
BP | GO:0006303 | double-strand break repair via nonhomologous end joining | IEP | Predicted GO |
BP | GO:0006464 | cellular protein modification process | IEP | Predicted GO |
BP | GO:0006468 | protein phosphorylation | IEP | Predicted GO |
BP | GO:0006813 | potassium ion transport | IEP | Predicted GO |
CC | GO:0008287 | protein serine/threonine phosphatase complex | IEP | Predicted GO |
MF | GO:0008483 | transaminase activity | IEP | Predicted GO |
MF | GO:0016301 | kinase activity | IEP | Predicted GO |
BP | GO:0016310 | phosphorylation | IEP | Predicted GO |
MF | GO:0016603 | glutaminyl-peptide cyclotransferase activity | IEP | Predicted GO |
MF | GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors | IEP | Predicted GO |
MF | GO:0016740 | transferase activity | IEP | Predicted GO |
MF | GO:0016755 | transferase activity, transferring amino-acyl groups | IEP | Predicted GO |
MF | GO:0016769 | transferase activity, transferring nitrogenous groups | IEP | Predicted GO |
MF | GO:0016773 | phosphotransferase activity, alcohol group as acceptor | IEP | Predicted GO |
MF | GO:0017150 | tRNA dihydrouridine synthase activity | IEP | Predicted GO |
BP | GO:0017186 | peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase | IEP | Predicted GO |
BP | GO:0018199 | peptidyl-glutamine modification | IEP | Predicted GO |
MF | GO:0019208 | phosphatase regulator activity | IEP | Predicted GO |
BP | GO:0019538 | protein metabolic process | IEP | Predicted GO |
MF | GO:0019888 | protein phosphatase regulator activity | IEP | Predicted GO |
MF | GO:0030145 | manganese ion binding | IEP | Predicted GO |
MF | GO:0031625 | ubiquitin protein ligase binding | IEP | Predicted GO |
BP | GO:0036211 | protein modification process | IEP | Predicted GO |
BP | GO:0043170 | macromolecule metabolic process | IEP | Predicted GO |
BP | GO:0043412 | macromolecule modification | IEP | Predicted GO |
BP | GO:0044238 | primary metabolic process | IEP | Predicted GO |
BP | GO:0044260 | cellular macromolecule metabolic process | IEP | Predicted GO |
MF | GO:0044389 | ubiquitin-like protein ligase binding | IEP | Predicted GO |
MF | GO:0050660 | flavin adenine dinucleotide binding | IEP | Predicted GO |
MF | GO:0140096 | catalytic activity, acting on a protein | IEP | Predicted GO |
CC | GO:1903293 | phosphatase complex | IEP | Predicted GO |
No external refs found! |