evm.model.contig_3597.6


Description : (at5g41360 : 736.0) Encodes XPB2, a DNA repair protein and transcription factor. Arabidopsis thaliana has duplicated XPB gene (AtXPB1 and AtXPB2, with high similarity to each other). XPB proteins are involved in both DNA repair and transcription, they are component of the transcription factor IIH (TFIIH) and are responsible for DNA helicase activity during nucleotide (nt) excision repair (NER). Complementation assays in yeast rad25 mutant strains suggest the involvement of AtXPB2 in DNA repair. Although both genes are expressed in a constitutive manner during the plant life cycle, Northern blot analyses suggest that light modulates the expression level of both XPB copies.; homolog of Xeroderma pigmentosum complementation group B 2 (XPB2); FUNCTIONS IN: in 7 functions; INVOLVED IN: response to UV-B, N-terminal protein myristoylation; EXPRESSED IN: whole plant; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: Restriction endonuclease, type I, R subunit/Type III, Res subunit (InterPro:IPR006935), DEAD-like helicase, N-terminal (InterPro:IPR014001), Xeroderma pigmentosum group B protein (XP-B) (InterPro:IPR001161), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: homolog of xeroderma pigmentosum complementation group B 1 (TAIR:AT5G41370.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 1472.0) & (original description: no original description)


Gene families : OG_42_0003616 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003616_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Porphyridium release: evm.model.contig_3597.6
Cluster HCCA clusters: Cluster_26

Target Alias Description ECC score Gene Family Method Actions
PSME_00044237-RA No alias (at5g41360 : 583.0) Encodes XPB2, a DNA repair protein... 0.01 Orthogroups_2024-Update
Sopen08g029660 No alias Helicase conserved C-terminal domain 0.03 Orthogroups_2024-Update
evm.model.tig00000949.17 No alias (at5g41360 : 573.0) Encodes XPB2, a DNA repair protein... 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0003677 DNA binding IEA InterProScan predictions
MF GO:0005524 ATP binding IEA InterProScan predictions
MF GO:0016787 hydrolase activity IEA InterProScan predictions
Type GO Term Name Evidence Source
CC GO:0000159 protein phosphatase type 2A complex IEP Predicted GO
BP GO:0000726 non-recombinational repair IEP Predicted GO
MF GO:0004518 nuclease activity IEP Predicted GO
MF GO:0004672 protein kinase activity IEP Predicted GO
BP GO:0006281 DNA repair IEP Predicted GO
BP GO:0006302 double-strand break repair IEP Predicted GO
BP GO:0006303 double-strand break repair via nonhomologous end joining IEP Predicted GO
BP GO:0006464 cellular protein modification process IEP Predicted GO
BP GO:0006468 protein phosphorylation IEP Predicted GO
BP GO:0006813 potassium ion transport IEP Predicted GO
CC GO:0008287 protein serine/threonine phosphatase complex IEP Predicted GO
MF GO:0008483 transaminase activity IEP Predicted GO
MF GO:0016301 kinase activity IEP Predicted GO
BP GO:0016310 phosphorylation IEP Predicted GO
MF GO:0016603 glutaminyl-peptide cyclotransferase activity IEP Predicted GO
MF GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors IEP Predicted GO
MF GO:0016740 transferase activity IEP Predicted GO
MF GO:0016755 transferase activity, transferring amino-acyl groups IEP Predicted GO
MF GO:0016769 transferase activity, transferring nitrogenous groups IEP Predicted GO
MF GO:0016773 phosphotransferase activity, alcohol group as acceptor IEP Predicted GO
MF GO:0017150 tRNA dihydrouridine synthase activity IEP Predicted GO
BP GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase IEP Predicted GO
BP GO:0018199 peptidyl-glutamine modification IEP Predicted GO
MF GO:0019208 phosphatase regulator activity IEP Predicted GO
BP GO:0019538 protein metabolic process IEP Predicted GO
MF GO:0019888 protein phosphatase regulator activity IEP Predicted GO
MF GO:0030145 manganese ion binding IEP Predicted GO
MF GO:0031625 ubiquitin protein ligase binding IEP Predicted GO
BP GO:0036211 protein modification process IEP Predicted GO
BP GO:0043170 macromolecule metabolic process IEP Predicted GO
BP GO:0043412 macromolecule modification IEP Predicted GO
BP GO:0044238 primary metabolic process IEP Predicted GO
BP GO:0044260 cellular macromolecule metabolic process IEP Predicted GO
MF GO:0044389 ubiquitin-like protein ligase binding IEP Predicted GO
MF GO:0050660 flavin adenine dinucleotide binding IEP Predicted GO
MF GO:0140096 catalytic activity, acting on a protein IEP Predicted GO
CC GO:1903293 phosphatase complex IEP Predicted GO
InterPro domains Description Start Stop
IPR006935 Helicase/UvrB_N 546 700
IPR032438 ERCC3_RAD25_C 726 961
IPR032830 XPB/Ssl2_N 287 410
No external refs found!