evm.model.contig_4443.18


Description : (at2g32920 : 135.0) Encodes a protein disulfide isomerase-like (PDIL) protein, a member of a multigene family within the thioredoxin (TRX) superfamily. Transcript levels for this gene are up-regulated in response to three different chemical inducers of ER stress (dithiothreitol, beta-mercaptoethanol, and tunicamycin). AtIRE1-2 does not appear to be required for this response, but the atbzip60 mutant has a diminished response.; PDI-like 2-3 (PDIL2-3); FUNCTIONS IN: protein disulfide isomerase activity; INVOLVED IN: response to endoplasmic reticulum stress; LOCATED IN: endoplasmic reticulum, plasma membrane, vacuole; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Disulphide isomerase (InterPro:IPR005788), Thioredoxin domain (InterPro:IPR013766), Thioredoxin, conserved site (InterPro:IPR017937), Thioredoxin-like subdomain (InterPro:IPR006662), Thioredoxin-like (InterPro:IPR017936), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: PDI-like 2-2 (TAIR:AT1G04980.1); Has 34824 Blast hits to 18409 proteins in 2879 species: Archae - 382; Bacteria - 17291; Metazoa - 5423; Fungi - 1895; Plants - 2648; Viruses - 40; Other Eukaryotes - 7145 (source: NCBI BLink). & (p38661|pdia6_medsa : 95.1) Probable protein disulfide-isomerase A6 precursor (EC 5.3.4.1) (P5) - Medicago sativa (Alfalfa) & (reliability: 270.0) & (original description: no original description)


Gene families : OG_42_0005698 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0005698_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Porphyridium release: evm.model.contig_4443.18
Cluster HCCA clusters: Cluster_60

Target Alias Description ECC score Gene Family Method Actions
Bradi4g31830 No alias PDI-like 2-2 0.02 Orthogroups_2024-Update
GRMZM2G376542 No alias PDI-like 2-3 0.02 Orthogroups_2024-Update
GRMZM2G389173 No alias PDI-like 2-2 0.02 Orthogroups_2024-Update
Potri.014G160000 No alias PDI-like 2-2 0.02 Orthogroups_2024-Update
Pp1s284_20V6 No alias protein disulfide isomerase 0.02 Orthogroups_2024-Update
Seita.2G225600.1 No alias protein disulfide isomerase *(PDI-M) & protein disulfide... 0.02 Orthogroups_2024-Update
Solyc07g049450 No alias Protein disulfide isomerase family (AHRD V3.3 *** A9CPA7_SOYBN) 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
BP GO:0045454 cell redox homeostasis IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0000062 fatty-acyl-CoA binding IEP Predicted GO
BP GO:0001510 RNA methylation IEP Predicted GO
MF GO:0005515 protein binding IEP Predicted GO
BP GO:0006270 DNA replication initiation IEP Predicted GO
BP GO:0006298 mismatch repair IEP Predicted GO
BP GO:0006400 tRNA modification IEP Predicted GO
BP GO:0006457 protein folding IEP Predicted GO
BP GO:0006650 glycerophospholipid metabolic process IEP Predicted GO
MF GO:0008378 galactosyltransferase activity IEP Predicted GO
BP GO:0030258 lipid modification IEP Predicted GO
BP GO:0030488 tRNA methylation IEP Predicted GO
MF GO:0030983 mismatched DNA binding IEP Predicted GO
CC GO:0031515 tRNA (m1A) methyltransferase complex IEP Predicted GO
BP GO:0032259 methylation IEP Predicted GO
MF GO:0033218 amide binding IEP Predicted GO
CC GO:0034708 methyltransferase complex IEP Predicted GO
BP GO:0043414 macromolecule methylation IEP Predicted GO
CC GO:0043527 tRNA methyltransferase complex IEP Predicted GO
BP GO:0044260 cellular macromolecule metabolic process IEP Predicted GO
BP GO:0046486 glycerolipid metabolic process IEP Predicted GO
BP GO:0046488 phosphatidylinositol metabolic process IEP Predicted GO
BP GO:0046834 lipid phosphorylation IEP Predicted GO
BP GO:0046854 phosphatidylinositol phosphorylation IEP Predicted GO
MF GO:0051082 unfolded protein binding IEP Predicted GO
MF GO:0051537 2 iron, 2 sulfur cluster binding IEP Predicted GO
MF GO:1901567 fatty acid derivative binding IEP Predicted GO
MF GO:1901681 sulfur compound binding IEP Predicted GO
InterPro domains Description Start Stop
IPR013766 Thioredoxin_domain 41 145
No external refs found!