Description : (at2g32920 : 135.0) Encodes a protein disulfide isomerase-like (PDIL) protein, a member of a multigene family within the thioredoxin (TRX) superfamily. Transcript levels for this gene are up-regulated in response to three different chemical inducers of ER stress (dithiothreitol, beta-mercaptoethanol, and tunicamycin). AtIRE1-2 does not appear to be required for this response, but the atbzip60 mutant has a diminished response.; PDI-like 2-3 (PDIL2-3); FUNCTIONS IN: protein disulfide isomerase activity; INVOLVED IN: response to endoplasmic reticulum stress; LOCATED IN: endoplasmic reticulum, plasma membrane, vacuole; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Disulphide isomerase (InterPro:IPR005788), Thioredoxin domain (InterPro:IPR013766), Thioredoxin, conserved site (InterPro:IPR017937), Thioredoxin-like subdomain (InterPro:IPR006662), Thioredoxin-like (InterPro:IPR017936), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: PDI-like 2-2 (TAIR:AT1G04980.1); Has 34824 Blast hits to 18409 proteins in 2879 species: Archae - 382; Bacteria - 17291; Metazoa - 5423; Fungi - 1895; Plants - 2648; Viruses - 40; Other Eukaryotes - 7145 (source: NCBI BLink). & (p38661|pdia6_medsa : 95.1) Probable protein disulfide-isomerase A6 precursor (EC 5.3.4.1) (P5) - Medicago sativa (Alfalfa) & (reliability: 270.0) & (original description: no original description)
Gene families : OG_42_0005698 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0005698_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Porphyridium release: evm.model.contig_4443.18 | |
Cluster | HCCA clusters: Cluster_60 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
Bradi4g31830 | No alias | PDI-like 2-2 | 0.02 | Orthogroups_2024-Update | |
GRMZM2G376542 | No alias | PDI-like 2-3 | 0.02 | Orthogroups_2024-Update | |
GRMZM2G389173 | No alias | PDI-like 2-2 | 0.02 | Orthogroups_2024-Update | |
Potri.014G160000 | No alias | PDI-like 2-2 | 0.02 | Orthogroups_2024-Update | |
Pp1s284_20V6 | No alias | protein disulfide isomerase | 0.02 | Orthogroups_2024-Update | |
Seita.2G225600.1 | No alias | protein disulfide isomerase *(PDI-M) & protein disulfide... | 0.02 | Orthogroups_2024-Update | |
Solyc07g049450 | No alias | Protein disulfide isomerase family (AHRD V3.3 *** A9CPA7_SOYBN) | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0045454 | cell redox homeostasis | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0000062 | fatty-acyl-CoA binding | IEP | Predicted GO |
BP | GO:0001510 | RNA methylation | IEP | Predicted GO |
MF | GO:0005515 | protein binding | IEP | Predicted GO |
BP | GO:0006270 | DNA replication initiation | IEP | Predicted GO |
BP | GO:0006298 | mismatch repair | IEP | Predicted GO |
BP | GO:0006400 | tRNA modification | IEP | Predicted GO |
BP | GO:0006457 | protein folding | IEP | Predicted GO |
BP | GO:0006650 | glycerophospholipid metabolic process | IEP | Predicted GO |
MF | GO:0008378 | galactosyltransferase activity | IEP | Predicted GO |
BP | GO:0030258 | lipid modification | IEP | Predicted GO |
BP | GO:0030488 | tRNA methylation | IEP | Predicted GO |
MF | GO:0030983 | mismatched DNA binding | IEP | Predicted GO |
CC | GO:0031515 | tRNA (m1A) methyltransferase complex | IEP | Predicted GO |
BP | GO:0032259 | methylation | IEP | Predicted GO |
MF | GO:0033218 | amide binding | IEP | Predicted GO |
CC | GO:0034708 | methyltransferase complex | IEP | Predicted GO |
BP | GO:0043414 | macromolecule methylation | IEP | Predicted GO |
CC | GO:0043527 | tRNA methyltransferase complex | IEP | Predicted GO |
BP | GO:0044260 | cellular macromolecule metabolic process | IEP | Predicted GO |
BP | GO:0046486 | glycerolipid metabolic process | IEP | Predicted GO |
BP | GO:0046488 | phosphatidylinositol metabolic process | IEP | Predicted GO |
BP | GO:0046834 | lipid phosphorylation | IEP | Predicted GO |
BP | GO:0046854 | phosphatidylinositol phosphorylation | IEP | Predicted GO |
MF | GO:0051082 | unfolded protein binding | IEP | Predicted GO |
MF | GO:0051537 | 2 iron, 2 sulfur cluster binding | IEP | Predicted GO |
MF | GO:1901567 | fatty acid derivative binding | IEP | Predicted GO |
MF | GO:1901681 | sulfur compound binding | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR013766 | Thioredoxin_domain | 41 | 145 |
No external refs found! |