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  5. evm.model.contig_4531.2

evm.model.contig_4531.2


Description : (p49079|akh1_maize : 300.0) Bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplast precursor (AK-HD 1) (AK-HSDH 1) [Includes: Aspartokinase (EC 2.7.2.4); Homoserine dehydrogenase (EC 1.1.1.3)] - Zea mays (Maize) & (at1g31230 : 293.0) Encodes a bifunctional aspartate kinase/homoserine dehydrogenase. These two activities catalyze the first and the third steps toward the synthesis of the essential amino acids threonine, isoleucine and methionine.; aspartate kinase-homoserine dehydrogenase i (AK-HSDH I); FUNCTIONS IN: homoserine dehydrogenase activity, aspartate kinase activity; INVOLVED IN: aspartate family amino acid biosynthetic process; LOCATED IN: chloroplast stroma, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aspartate/glutamate/uridylate kinase (InterPro:IPR001048), Homoserine dehydrogenase, catalytic (InterPro:IPR001342), Amino acid-binding ACT (InterPro:IPR002912), Aspartate/homoserine dehydrogenase, NAD-binding (InterPro:IPR005106), Aspartate kinase, conserved site (InterPro:IPR018042), Bifunctional aspartokinase/homoserine dehydrogenase I (InterPro:IPR011147), NAD(P)-binding domain (InterPro:IPR016040), Aspartate kinase domain (InterPro:IPR001341), Homoserine dehydrogenase, conserved site (InterPro:IPR019811); BEST Arabidopsis thaliana protein match is: aspartate kinase-homoserine dehydrogenase ii (TAIR:AT4G19710.2); Has 17266 Blast hits to 16993 proteins in 2572 species: Archae - 397; Bacteria - 11403; Metazoa - 7; Fungi - 300; Plants - 257; Viruses - 0; Other Eukaryotes - 4902 (source: NCBI BLink). & (reliability: 586.0) & (original description: no original description)


Gene families : OG_42_0003092 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003092_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood Porphyridium release: evm.model.contig_4531.2
Cluster HCCA clusters: Cluster_34

Target Alias Description ECC score Gene Family Method Actions
Cre02.g109550 No alias aspartate kinase-homoserine dehydrogenase ii 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
BP GO:0006520 cellular amino acid metabolic process IEA InterProScan predictions
MF GO:0016491 oxidoreductase activity IEA InterProScan predictions
MF GO:0050661 NADP binding IEA InterProScan predictions
BP GO:0055114 oxidation-reduction process IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0001882 nucleoside binding IEP Predicted GO
MF GO:0001883 purine nucleoside binding IEP Predicted GO
MF GO:0004177 aminopeptidase activity IEP Predicted GO
MF GO:0004512 inositol-3-phosphate synthase activity IEP Predicted GO
MF GO:0004820 glycine-tRNA ligase activity IEP Predicted GO
MF GO:0004853 uroporphyrinogen decarboxylase activity IEP Predicted GO
MF GO:0005525 GTP binding IEP Predicted GO
BP GO:0006020 inositol metabolic process IEP Predicted GO
BP GO:0006021 inositol biosynthetic process IEP Predicted GO
BP GO:0006066 alcohol metabolic process IEP Predicted GO
BP GO:0006426 glycyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006605 protein targeting IEP Predicted GO
BP GO:0006612 protein targeting to membrane IEP Predicted GO
BP GO:0006613 cotranslational protein targeting to membrane IEP Predicted GO
BP GO:0006614 SRP-dependent cotranslational protein targeting to membrane IEP Predicted GO
BP GO:0006778 porphyrin-containing compound metabolic process IEP Predicted GO
BP GO:0006779 porphyrin-containing compound biosynthetic process IEP Predicted GO
BP GO:0008104 protein localization IEP Predicted GO
MF GO:0008312 7S RNA binding IEP Predicted GO
BP GO:0008654 phospholipid biosynthetic process IEP Predicted GO
BP GO:0015031 protein transport IEP Predicted GO
BP GO:0015833 peptide transport IEP Predicted GO
MF GO:0016872 intramolecular lyase activity IEP Predicted GO
MF GO:0019001 guanyl nucleotide binding IEP Predicted GO
BP GO:0019751 polyol metabolic process IEP Predicted GO
MF GO:0032549 ribonucleoside binding IEP Predicted GO
MF GO:0032550 purine ribonucleoside binding IEP Predicted GO
MF GO:0032561 guanyl ribonucleotide binding IEP Predicted GO
BP GO:0033014 tetrapyrrole biosynthetic process IEP Predicted GO
BP GO:0033036 macromolecule localization IEP Predicted GO
BP GO:0033365 protein localization to organelle IEP Predicted GO
BP GO:0034637 cellular carbohydrate biosynthetic process IEP Predicted GO
BP GO:0042886 amide transport IEP Predicted GO
BP GO:0044262 cellular carbohydrate metabolic process IEP Predicted GO
BP GO:0045047 protein targeting to ER IEP Predicted GO
BP GO:0045184 establishment of protein localization IEP Predicted GO
BP GO:0046165 alcohol biosynthetic process IEP Predicted GO
BP GO:0046173 polyol biosynthetic process IEP Predicted GO
CC GO:0048500 signal recognition particle IEP Predicted GO
MF GO:0070567 cytidylyltransferase activity IEP Predicted GO
BP GO:0070972 protein localization to endoplasmic reticulum IEP Predicted GO
BP GO:0071702 organic substance transport IEP Predicted GO
BP GO:0071705 nitrogen compound transport IEP Predicted GO
BP GO:0072594 establishment of protein localization to organelle IEP Predicted GO
BP GO:0072599 establishment of protein localization to endoplasmic reticulum IEP Predicted GO
BP GO:0072657 protein localization to membrane IEP Predicted GO
BP GO:0090150 establishment of protein localization to membrane IEP Predicted GO
BP GO:1901615 organic hydroxy compound metabolic process IEP Predicted GO
BP GO:1901617 organic hydroxy compound biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR001342 HDH_cat 168 367
IPR005106 Asp/hSer_DH_NAD-bd 16 154
No external refs found!