Description : (at5g09230 : 171.0) Encodes SRT2, a member of the SIR2 (sirtuin) family HDAC (histone deacetylase) (SRT1/AT5g55760, SRT2/AT5G09230).; sirtuin 2 (SRT2); FUNCTIONS IN: NAD binding, DNA binding, zinc ion binding, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; INVOLVED IN: chromatin silencing, defense response to bacterium, negative regulation of defense response, regulation of transcription, DNA-dependent; LOCATED IN: chromatin silencing complex, nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: NAD-dependent histone deacetylase, silent information regulator Sir2 (InterPro:IPR003000); BEST Arabidopsis thaliana protein match is: sirtuin 1 (TAIR:AT5G55760.1); Has 6471 Blast hits to 6454 proteins in 2013 species: Archae - 152; Bacteria - 3779; Metazoa - 822; Fungi - 681; Plants - 106; Viruses - 0; Other Eukaryotes - 931 (source: NCBI BLink). & (reliability: 342.0) & (original description: no original description)
Gene families : OG_42_0007493 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0007493_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Porphyridium release: evm.model.contig_508.6 | |
Cluster | HCCA clusters: Cluster_78 |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0070403 | NAD+ binding | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005096 | GTPase activator activity | IEP | Predicted GO |
CC | GO:0005783 | endoplasmic reticulum | IEP | Predicted GO |
BP | GO:0006605 | protein targeting | IEP | Predicted GO |
MF | GO:0008047 | enzyme activator activity | IEP | Predicted GO |
MF | GO:0015035 | protein disulfide oxidoreductase activity | IEP | Predicted GO |
MF | GO:0015036 | disulfide oxidoreductase activity | IEP | Predicted GO |
MF | GO:0030695 | GTPase regulator activity | IEP | Predicted GO |
BP | GO:0033365 | protein localization to organelle | IEP | Predicted GO |
BP | GO:0034613 | cellular protein localization | IEP | Predicted GO |
BP | GO:0045047 | protein targeting to ER | IEP | Predicted GO |
MF | GO:0060589 | nucleoside-triphosphatase regulator activity | IEP | Predicted GO |
BP | GO:0070727 | cellular macromolecule localization | IEP | Predicted GO |
BP | GO:0070972 | protein localization to endoplasmic reticulum | IEP | Predicted GO |
BP | GO:0072594 | establishment of protein localization to organelle | IEP | Predicted GO |
BP | GO:0072599 | establishment of protein localization to endoplasmic reticulum | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR003000 | Sirtuin | 43 | 256 |
No external refs found! |