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  5. evm.model.contig_568.4

evm.model.contig_568.4


Description : (at5g13570 : 165.0) Encodes DCP2 with mRNA decapping activity. DCP2 forms a mRNA decapping complex with DCP1 (At1g08370) and VCS (VARICOSE) (At3g13300). Recombinant DCP2 is enzymatically active in vitro, generating from capped mRNAs m7GDP, and 5í-phosphorylated mRNAs. DCP1, DCP2 and VCS colocalize in cytoplasmic loci, which are putative Arabidopsis mRNA processing bodies. Null mutants of DCP1, DCP2, and VCS accumulate capped mRNAs with a reduced degradation rate. These mutants also share a similar lethal phenotype at the seedling cotyledon stage, with disorganized veins, swollen root hairs, and altered epidermal cell morphology. The protein was shown by immunoprecipitation not to interact with DCP1.; decapping 2 (DCP2); CONTAINS InterPro DOMAIN/s: NUDIX hydrolase domain-like (InterPro:IPR015797), Dcp2, box A (InterPro:IPR007722), NUDIX hydrolase domain (InterPro:IPR000086). & (reliability: 330.0) & (original description: no original description)


Gene families : OG_42_0005146 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0005146_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood Porphyridium release: evm.model.contig_568.4
Cluster HCCA clusters: Cluster_26

Target Alias Description ECC score Gene Family Method Actions
GRMZM2G150209 No alias decapping 2 0.01 Orthogroups_2024-Update
LOC_Os02g56210 No alias hydrolase, NUDIX family, domain containing protein, expressed 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0003723 RNA binding IEA InterProScan predictions
MF GO:0016787 hydrolase activity IEA InterProScan predictions
MF GO:0030145 manganese ion binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0004842 ubiquitin-protein transferase activity IEP Predicted GO
MF GO:0005048 signal sequence binding IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
BP GO:0006508 proteolysis IEP Predicted GO
BP GO:0006621 protein retention in ER lumen IEP Predicted GO
BP GO:0006811 ion transport IEP Predicted GO
BP GO:0006812 cation transport IEP Predicted GO
BP GO:0006813 potassium ion transport IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
MF GO:0008233 peptidase activity IEP Predicted GO
BP GO:0015672 monovalent inorganic cation transport IEP Predicted GO
MF GO:0019787 ubiquitin-like protein transferase activity IEP Predicted GO
BP GO:0030001 metal ion transport IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
BP GO:0032507 maintenance of protein location in cell IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
BP GO:0035437 maintenance of protein localization in endoplasmic reticulum IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0042277 peptide binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
BP GO:0045185 maintenance of protein location IEP Predicted GO
MF GO:0046923 ER retention sequence binding IEP Predicted GO
BP GO:0051235 maintenance of location IEP Predicted GO
BP GO:0051651 maintenance of location in cell IEP Predicted GO
BP GO:0072595 maintenance of protein localization in organelle IEP Predicted GO
MF GO:0140096 catalytic activity, acting on a protein IEP Predicted GO
InterPro domains Description Start Stop
IPR000086 NUDIX_hydrolase_dom 328 440
IPR007722 DCP2_BoxA 239 321
No external refs found!