Description : (at1g50030 : 714.0) Related to TOR proteins from yeast and mammals, regulators of cell growth in response to nutrient availability. TOR proteins belong to the family of phosphatidylinositol 3-kinase and are targets of the antiproliferative drug rapamycin. AtTOR binds the yeast FKBP12 protein in the presence of Rapamycin, is involved in embryogenesis and is expressed in embryos, endosperm and meristems.; target of rapamycin (TOR); FUNCTIONS IN: protein binding, 1-phosphatidylinositol-3-kinase activity; INVOLVED IN: embryo development ending in seed dormancy; LOCATED IN: chloroplast; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Phosphatidylinositol 3-/4-kinase, catalytic (InterPro:IPR000403), FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding (InterPro:IPR009076), Armadillo-like helical (InterPro:IPR011989), Protein kinase-like domain (InterPro:IPR011009), PIK-related kinase, FAT (InterPro:IPR003151), PIK-related kinase (InterPro:IPR014009), Armadillo-type fold (InterPro:IPR016024), Phosphatidylinositol 3/4-kinase, conserved site (InterPro:IPR018936), PIK-related kinase, FATC (InterPro:IPR003152); BEST Arabidopsis thaliana protein match is: Ataxia telangiectasia-mutated and RAD3-related (TAIR:AT5G40820.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (q5z987|atr_orysa : 170.0) Serine/threonine-protein kinase ATR (EC 2.7.11.1) - Oryza sativa (Rice) & (reliability: 1428.0) & (original description: no original description)
Gene families : OG_42_0004193 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004193_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Porphyridium release: evm.model.contig_798.1 | |
Cluster | HCCA clusters: Cluster_15 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
413509 | No alias | target of rapamycin | 0.01 | Orthogroups_2024-Update | |
Bradi2g28007 | No alias | target of rapamycin | 0.02 | Orthogroups_2024-Update | |
Glyma.11G002600 | No alias | target of rapamycin | 0.02 | Orthogroups_2024-Update | |
PSME_00000566-RA | No alias | (at1g50030 : 174.0) Related to TOR proteins from yeast... | 0.01 | Orthogroups_2024-Update | |
PSME_00000569-RA | No alias | (at1g50030 : 399.0) Related to TOR proteins from yeast... | 0.01 | Orthogroups_2024-Update | |
Potri.009G084500 | No alias | target of rapamycin | 0.01 | Orthogroups_2024-Update | |
Pp1s448_6V6 | No alias | target of rapamycin | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005515 | protein binding | IEA | InterProScan predictions |
MF | GO:0044877 | protein-containing complex binding | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003677 | DNA binding | IEP | Predicted GO |
MF | GO:0003909 | DNA ligase activity | IEP | Predicted GO |
MF | GO:0003911 | DNA ligase (NAD+) activity | IEP | Predicted GO |
MF | GO:0004523 | RNA-DNA hybrid ribonuclease activity | IEP | Predicted GO |
MF | GO:0004842 | ubiquitin-protein transferase activity | IEP | Predicted GO |
BP | GO:0006139 | nucleobase-containing compound metabolic process | IEP | Predicted GO |
BP | GO:0006259 | DNA metabolic process | IEP | Predicted GO |
BP | GO:0006260 | DNA replication | IEP | Predicted GO |
BP | GO:0006281 | DNA repair | IEP | Predicted GO |
BP | GO:0006950 | response to stress | IEP | Predicted GO |
BP | GO:0006974 | cellular response to DNA damage stimulus | IEP | Predicted GO |
MF | GO:0008234 | cysteine-type peptidase activity | IEP | Predicted GO |
BP | GO:0016579 | protein deubiquitination | IEP | Predicted GO |
MF | GO:0016740 | transferase activity | IEP | Predicted GO |
MF | GO:0016757 | transferase activity, transferring glycosyl groups | IEP | Predicted GO |
MF | GO:0016780 | phosphotransferase activity, for other substituted phosphate groups | IEP | Predicted GO |
MF | GO:0019783 | ubiquitin-like protein-specific protease activity | IEP | Predicted GO |
MF | GO:0019787 | ubiquitin-like protein transferase activity | IEP | Predicted GO |
BP | GO:0033554 | cellular response to stress | IEP | Predicted GO |
MF | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity | IEP | Predicted GO |
MF | GO:0043138 | 3'-5' DNA helicase activity | IEP | Predicted GO |
MF | GO:0043140 | ATP-dependent 3'-5' DNA helicase activity | IEP | Predicted GO |
CC | GO:0043226 | organelle | IEP | Predicted GO |
CC | GO:0043227 | membrane-bounded organelle | IEP | Predicted GO |
CC | GO:0043229 | intracellular organelle | IEP | Predicted GO |
CC | GO:0043231 | intracellular membrane-bounded organelle | IEP | Predicted GO |
BP | GO:0050896 | response to stimulus | IEP | Predicted GO |
BP | GO:0051716 | cellular response to stimulus | IEP | Predicted GO |
BP | GO:0070646 | protein modification by small protein removal | IEP | Predicted GO |
BP | GO:0070647 | protein modification by small protein conjugation or removal | IEP | Predicted GO |
BP | GO:0090304 | nucleic acid metabolic process | IEP | Predicted GO |
MF | GO:0101005 | ubiquitinyl hydrolase activity | IEP | Predicted GO |
MF | GO:0140097 | catalytic activity, acting on DNA | IEP | Predicted GO |
No external refs found! |