Solyc01g109830

Description : Bifunctional dihydrofolate reductase-thymidylate synthase (AHRD V3.3 *** K4B3J6_SOLLC)

Gene families : OG_42_0004548 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004548_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Solanum release: Solyc01g109830
Cluster	HCCA clusters: Cluster_199

Target	Alias	Description	ECC score	Gene Family Method	Actions
Cre17.g715900	No alias	thymidylate synthase 2	0.01	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
BP	GO:0001505	regulation of neurotransmitter levels	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004146	dihydrofolate reductase activity	IEA	InterProScan predictions
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006544	glycine metabolic process	None	Extended
BP	GO:0006545	glycine biosynthetic process	IEA	InterProScan predictions
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006753	nucleoside phosphate metabolic process	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008652	cellular amino acid biosynthetic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009069	serine family amino acid metabolic process	None	Extended
BP	GO:0009070	serine family amino acid biosynthetic process	None	Extended
BP	GO:0009117	nucleotide metabolic process	None	Extended
BP	GO:0009165	nucleotide biosynthetic process	IEA	InterProScan predictions
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016053	organic acid biosynthetic process	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	None	Extended
MF	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	None	Extended
BP	GO:0017144	drug metabolic process	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0019637	organophosphate metabolic process	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034654	nucleobase-containing compound biosynthetic process	None	Extended
BP	GO:0042133	neurotransmitter metabolic process	None	Extended
BP	GO:0042136	neurotransmitter biosynthetic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0044283	small molecule biosynthetic process	None	Extended
BP	GO:0046394	carboxylic acid biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0055086	nucleobase-containing small molecule metabolic process	None	Extended
BP	GO:0055114	oxidation-reduction process	IEA	InterProScan predictions
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0065008	regulation of biological quality	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090407	organophosphate biosynthetic process	None	Extended
BP	GO:1901293	nucleoside phosphate biosynthetic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended
BP	GO:1901605	alpha-amino acid metabolic process	None	Extended
BP	GO:1901607	alpha-amino acid biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity	IEP	Predicted GO
MF	GO:0003872	6-phosphofructokinase activity	IEP	Predicted GO
MF	GO:0003968	RNA-directed 5'-3' RNA polymerase activity	IEP	Predicted GO
MF	GO:0003993	acid phosphatase activity	IEP	Predicted GO
MF	GO:0004175	endopeptidase activity	IEP	Predicted GO
MF	GO:0004190	aspartic-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004602	glutathione peroxidase activity	IEP	Predicted GO
BP	GO:0006886	intracellular protein transport	IEP	Predicted GO
BP	GO:0006888	ER to Golgi vesicle-mediated transport	IEP	Predicted GO
BP	GO:0008104	protein localization	IEP	Predicted GO
MF	GO:0008233	peptidase activity	IEP	Predicted GO
MF	GO:0008237	metallopeptidase activity	IEP	Predicted GO
MF	GO:0008443	phosphofructokinase activity	IEP	Predicted GO
MF	GO:0008536	Ran GTPase binding	IEP	Predicted GO
MF	GO:0008641	ubiquitin-like modifier activating enzyme activity	IEP	Predicted GO
MF	GO:0010181	FMN binding	IEP	Predicted GO
BP	GO:0015031	protein transport	IEP	Predicted GO
BP	GO:0015833	peptide transport	IEP	Predicted GO
BP	GO:0016192	vesicle-mediated transport	IEP	Predicted GO
MF	GO:0016787	hydrolase activity	IEP	Predicted GO
MF	GO:0016791	phosphatase activity	IEP	Predicted GO
MF	GO:0016874	ligase activity	IEP	Predicted GO
MF	GO:0016877	ligase activity, forming carbon-sulfur bonds	IEP	Predicted GO
MF	GO:0019200	carbohydrate kinase activity	IEP	Predicted GO
CC	GO:0019773	proteasome core complex, alpha-subunit complex	IEP	Predicted GO
CC	GO:0030117	membrane coat	IEP	Predicted GO
CC	GO:0030127	COPII vesicle coat	IEP	Predicted GO
MF	GO:0032182	ubiquitin-like protein binding	IEP	Predicted GO
MF	GO:0032266	phosphatidylinositol-3-phosphate binding	IEP	Predicted GO
BP	GO:0033036	macromolecule localization	IEP	Predicted GO
MF	GO:0035091	phosphatidylinositol binding	IEP	Predicted GO
MF	GO:0042578	phosphoric ester hydrolase activity	IEP	Predicted GO
BP	GO:0042886	amide transport	IEP	Predicted GO
MF	GO:0043130	ubiquitin binding	IEP	Predicted GO
BP	GO:0045184	establishment of protein localization	IEP	Predicted GO
BP	GO:0046907	intracellular transport	IEP	Predicted GO
BP	GO:0051259	protein complex oligomerization	IEP	Predicted GO
BP	GO:0051260	protein homooligomerization	IEP	Predicted GO
BP	GO:0051641	cellular localization	IEP	Predicted GO
BP	GO:0051649	establishment of localization in cell	IEP	Predicted GO
MF	GO:0070001	aspartic-type peptidase activity	IEP	Predicted GO
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	IEP	Predicted GO
MF	GO:0070569	uridylyltransferase activity	IEP	Predicted GO
BP	GO:0071702	organic substance transport	IEP	Predicted GO
BP	GO:0071705	nitrogen compound transport	IEP	Predicted GO
MF	GO:1901981	phosphatidylinositol phosphate binding	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR023451	Thymidate_synth/dCMP_Mease	246	527
IPR001796	DHFR_dom	25	200

External Links

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Solyc01g109830

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation