PSME_00000068-RA


Description : (at2g26260 : 555.0) Encodes an enzyme with 3&#946;-hydroxysteroid dehydrogenase/C4-decarboxylase activity <i>in vitro</i>. The activity of the enzyme was determined using microsomal extracts of yeast overexpressing the <i>Arabidopsis</i> gene. Cytosolic fractions failed to be associated to the activity, leading to the speculation that the enzyme is membrane-bound.; 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2 (3BETAHSD/D2); FUNCTIONS IN: 3-beta-hydroxy-delta5-steroid dehydrogenase activity, sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity; INVOLVED IN: steroid biosynthetic process, metabolic process; LOCATED IN: membrane; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: Reticulon (InterPro:IPR003388), 3-beta hydroxysteroid dehydrogenase/isomerase (InterPro:IPR002225), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 1 (TAIR:AT1G47290.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 1110.0) & (original description: no original description)


Gene families : OG_42_0001400 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001400_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00000068-RA
Cluster HCCA clusters: Cluster_188

Target Alias Description ECC score Gene Family Method Actions
A4A49_21763 No alias 3beta-hydroxysteroid-dehydrogenasedecarboxylase isoform 2 0.04 Orthogroups_2024-Update
Cre12.g518650 No alias 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 1 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity IEA InterProScan predictions
BP GO:0006694 steroid biosynthetic process IEA InterProScan predictions
MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA InterProScan predictions
BP GO:0055114 oxidation-reduction process IEA InterProScan predictions
Type GO Term Name Evidence Source
BP GO:0001505 regulation of neurotransmitter levels IEP Predicted GO
MF GO:0003899 DNA-directed 5'-3' RNA polymerase activity IEP Predicted GO
MF GO:0004375 glycine dehydrogenase (decarboxylating) activity IEP Predicted GO
MF GO:0004455 ketol-acid reductoisomerase activity IEP Predicted GO
MF GO:0004672 protein kinase activity IEP Predicted GO
MF GO:0005488 binding IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
BP GO:0006464 cellular protein modification process IEP Predicted GO
BP GO:0006468 protein phosphorylation IEP Predicted GO
BP GO:0006520 cellular amino acid metabolic process IEP Predicted GO
BP GO:0006544 glycine metabolic process IEP Predicted GO
BP GO:0006546 glycine catabolic process IEP Predicted GO
BP GO:0006793 phosphorus metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
BP GO:0006807 nitrogen compound metabolic process IEP Predicted GO
BP GO:0008037 cell recognition IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
BP GO:0009063 cellular amino acid catabolic process IEP Predicted GO
BP GO:0009069 serine family amino acid metabolic process IEP Predicted GO
BP GO:0009071 serine family amino acid catabolic process IEP Predicted GO
BP GO:0009081 branched-chain amino acid metabolic process IEP Predicted GO
BP GO:0009082 branched-chain amino acid biosynthetic process IEP Predicted GO
BP GO:0016054 organic acid catabolic process IEP Predicted GO
MF GO:0016301 kinase activity IEP Predicted GO
BP GO:0016310 phosphorylation IEP Predicted GO
MF GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors IEP Predicted GO
MF GO:0016642 oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor IEP Predicted GO
MF GO:0016772 transferase activity, transferring phosphorus-containing groups IEP Predicted GO
MF GO:0016773 phosphotransferase activity, alcohol group as acceptor IEP Predicted GO
MF GO:0019842 vitamin binding IEP Predicted GO
BP GO:0022414 reproductive process IEP Predicted GO
MF GO:0030170 pyridoxal phosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
BP GO:0036211 protein modification process IEP Predicted GO
BP GO:0042133 neurotransmitter metabolic process IEP Predicted GO
BP GO:0042135 neurotransmitter catabolic process IEP Predicted GO
MF GO:0043167 ion binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
BP GO:0043412 macromolecule modification IEP Predicted GO
BP GO:0044282 small molecule catabolic process IEP Predicted GO
BP GO:0046395 carboxylic acid catabolic process IEP Predicted GO
BP GO:0048544 recognition of pollen IEP Predicted GO
MF GO:0070279 vitamin B6 binding IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
BP GO:1901564 organonitrogen compound metabolic process IEP Predicted GO
BP GO:1901606 alpha-amino acid catabolic process IEP Predicted GO
InterPro domains Description Start Stop
IPR003388 Reticulon 471 627
IPR002225 3Beta_OHSteriod_DH/Estase 19 89
IPR002225 3Beta_OHSteriod_DH/Estase 110 370
No external refs found!