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  5. PSME_00000320-RA

PSME_00000320-RA


Description : (at4g32700 : 939.0) Encodes a homolog of Drosophila MUS308 and mammalian DNA polymerase, which prevent spontaneous or DNA damage-induced production of DNA double strand breaks. Two conserved functional domains: an N-terminal superfamily II DNA/RNA helicase domain and a C-terminal prokaryotic-type DNA polymerase I domain. Required for regulated cell division and differentiation in meristems. Mutant plants show morphological defects, such as short roots, serrated leaves, and fasciation, as well as defective patterns of cell division and differentiation in the meristem. Mutant plants had 2.5 to 4.5-fold higher expression of ATGR1, ATBRCA1 and RAD51 genes. TEB is required for normal progression of DNA replication and for correct expression of genes during development.; helicases;ATP-dependent helicases;nucleic acid binding;ATP binding;DNA-directed DNA polymerases;DNA binding; FUNCTIONS IN: in 6 functions; INVOLVED IN: regulation of gene expression, DNA replication, DNA recombination, photomorphogenesis; EXPRESSED IN: 6 plant structures; EXPRESSED DURING: petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA-directed DNA polymerase, family A, palm domain (InterPro:IPR001098), DNA/RNA helicase, C-terminal (InterPro:IPR001650), DNA polymerase A domain (InterPro:IPR002298), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: U5 small nuclear ribonucleoprotein helicase (TAIR:AT2G42270.1); Has 17628 Blast hits to 16579 proteins in 2941 species: Archae - 600; Bacteria - 7507; Metazoa - 1254; Fungi - 1190; Plants - 590; Viruses - 412; Other Eukaryotes - 6075 (source: NCBI BLink). & (reliability: 1878.0) & (original description: no original description)


Gene families : OG_42_0004411 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004411_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00000320-RA
Cluster HCCA clusters: Cluster_253


Type GO Term Name Evidence Source
MF GO:0003676 nucleic acid binding IEA InterProScan predictions
MF GO:0005524 ATP binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0000287 magnesium ion binding IEP Predicted GO
MF GO:0001871 pattern binding IEP Predicted GO
MF GO:0003824 catalytic activity IEP Predicted GO
BP GO:0006284 base-excision repair IEP Predicted GO
MF GO:0010333 terpene synthase activity IEP Predicted GO
MF GO:0016491 oxidoreductase activity IEP Predicted GO
MF GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEP Predicted GO
MF GO:0016835 carbon-oxygen lyase activity IEP Predicted GO
MF GO:0016838 carbon-oxygen lyase activity, acting on phosphates IEP Predicted GO
MF GO:0030246 carbohydrate binding IEP Predicted GO
MF GO:0030247 polysaccharide binding IEP Predicted GO
MF GO:0030599 pectinesterase activity IEP Predicted GO
BP GO:0042545 cell wall modification IEP Predicted GO
MF GO:0043531 ADP binding IEP Predicted GO
BP GO:0045229 external encapsulating structure organization IEP Predicted GO
MF GO:0048037 cofactor binding IEP Predicted GO
MF GO:0050660 flavin adenine dinucleotide binding IEP Predicted GO
MF GO:0052689 carboxylic ester hydrolase activity IEP Predicted GO
BP GO:0055114 oxidation-reduction process IEP Predicted GO
BP GO:0071554 cell wall organization or biogenesis IEP Predicted GO
BP GO:0071555 cell wall organization IEP Predicted GO
MF GO:0071949 FAD binding IEP Predicted GO
InterPro domains Description Start Stop
IPR001650 Helicase_C 903 1054
IPR011545 DEAD/DEAH_box_helicase_dom 674 847
No external refs found!