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Description : (at2g32000 : 130.0) DNA topoisomerase, type IA, core; FUNCTIONS IN: DNA topoisomerase activity, DNA topoisomerase type I activity, DNA binding, nucleic acid binding; INVOLVED IN: DNA topological change, DNA unwinding involved in replication, DNA metabolic process; LOCATED IN: endomembrane system, chromosome; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Toprim domain, subgroup (InterPro:IPR006154), DNA topoisomerase, type IA, central region, subdomain 1 (InterPro:IPR013824), DNA topoisomerase, type IA, core (InterPro:IPR000380), Toprim domain (InterPro:IPR006171), DNA topoisomerase, type IA, DNA-binding (InterPro:IPR003602), DNA topoisomerase, type IA, domain 2 (InterPro:IPR003601), DNA topoisomerase, type IA, central (InterPro:IPR013497), DNA topoisomerase, type IA, central region, subdomain 3 (InterPro:IPR013826); BEST Arabidopsis thaliana protein match is: topoisomerase 3alpha (TAIR:AT5G63920.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 260.0) & (original description: no original description)
Gene families : OG_42_0002596 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0002596_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | Pseudotsuga release: PSME_00000740-RA | |
| Cluster | HCCA clusters: Cluster_102 |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No GO annotation available for this sequence |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0000166 | nucleotide binding | IEP | Predicted GO |
| MF | GO:0003690 | double-stranded DNA binding | IEP | Predicted GO |
| MF | GO:0003824 | catalytic activity | IEP | Predicted GO |
| MF | GO:0004601 | peroxidase activity | IEP | Predicted GO |
| BP | GO:0006020 | inositol metabolic process | IEP | Predicted GO |
| BP | GO:0006066 | alcohol metabolic process | IEP | Predicted GO |
| BP | GO:0006259 | DNA metabolic process | IEP | Predicted GO |
| BP | GO:0006281 | DNA repair | IEP | Predicted GO |
| BP | GO:0006298 | mismatch repair | IEP | Predicted GO |
| BP | GO:0006631 | fatty acid metabolic process | IEP | Predicted GO |
| BP | GO:0006633 | fatty acid biosynthetic process | IEP | Predicted GO |
| BP | GO:0006855 | drug transmembrane transport | IEP | Predicted GO |
| BP | GO:0006950 | response to stress | IEP | Predicted GO |
| BP | GO:0006974 | cellular response to DNA damage stimulus | IEP | Predicted GO |
| BP | GO:0006979 | response to oxidative stress | IEP | Predicted GO |
| MF | GO:0015238 | drug transmembrane transporter activity | IEP | Predicted GO |
| BP | GO:0015893 | drug transport | IEP | Predicted GO |
| MF | GO:0016209 | antioxidant activity | IEP | Predicted GO |
| MF | GO:0016462 | pyrophosphatase activity | IEP | Predicted GO |
| MF | GO:0016684 | oxidoreductase activity, acting on peroxide as acceptor | IEP | Predicted GO |
| MF | GO:0016746 | transferase activity, transferring acyl groups | IEP | Predicted GO |
| MF | GO:0016747 | transferase activity, transferring acyl groups other than amino-acyl groups | IEP | Predicted GO |
| MF | GO:0016790 | thiolester hydrolase activity | IEP | Predicted GO |
| MF | GO:0016817 | hydrolase activity, acting on acid anhydrides | IEP | Predicted GO |
| MF | GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | IEP | Predicted GO |
| MF | GO:0017076 | purine nucleotide binding | IEP | Predicted GO |
| MF | GO:0017111 | nucleoside-triphosphatase activity | IEP | Predicted GO |
| BP | GO:0019310 | inositol catabolic process | IEP | Predicted GO |
| BP | GO:0019751 | polyol metabolic process | IEP | Predicted GO |
| MF | GO:0020037 | heme binding | IEP | Predicted GO |
| MF | GO:0022804 | active transmembrane transporter activity | IEP | Predicted GO |
| MF | GO:0030983 | mismatched DNA binding | IEP | Predicted GO |
| MF | GO:0032553 | ribonucleotide binding | IEP | Predicted GO |
| MF | GO:0032555 | purine ribonucleotide binding | IEP | Predicted GO |
| BP | GO:0032787 | monocarboxylic acid metabolic process | IEP | Predicted GO |
| BP | GO:0033554 | cellular response to stress | IEP | Predicted GO |
| MF | GO:0035639 | purine ribonucleoside triphosphate binding | IEP | Predicted GO |
| MF | GO:0043168 | anion binding | IEP | Predicted GO |
| BP | GO:0044275 | cellular carbohydrate catabolic process | IEP | Predicted GO |
| BP | GO:0046164 | alcohol catabolic process | IEP | Predicted GO |
| BP | GO:0046174 | polyol catabolic process | IEP | Predicted GO |
| MF | GO:0046906 | tetrapyrrole binding | IEP | Predicted GO |
| MF | GO:0048037 | cofactor binding | IEP | Predicted GO |
| MF | GO:0050113 | inositol oxygenase activity | IEP | Predicted GO |
| BP | GO:0050896 | response to stimulus | IEP | Predicted GO |
| BP | GO:0051716 | cellular response to stimulus | IEP | Predicted GO |
| BP | GO:0055114 | oxidation-reduction process | IEP | Predicted GO |
| BP | GO:0072330 | monocarboxylic acid biosynthetic process | IEP | Predicted GO |
| MF | GO:0097367 | carbohydrate derivative binding | IEP | Predicted GO |
| MF | GO:1901265 | nucleoside phosphate binding | IEP | Predicted GO |
| BP | GO:1901615 | organic hydroxy compound metabolic process | IEP | Predicted GO |
| BP | GO:1901616 | organic hydroxy compound catabolic process | IEP | Predicted GO |
No InterPro domains available for this sequence
| No external refs found! |