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  5. PSME_00001085-RA

PSME_00001085-RA


Description : (at5g19400 : 141.0) Encodes SMG7, a protein that possesses an evolutionarily conserved EST1 domain and exhibits strong homology to human SMG6 (EST1A) and SMG7 (EST1C) proteins. SMG7 plays an evolutionarily conserved role in nonsense-mediated RNA decay (NMD). Required for exit from meiosis. Hypomorphic smg7 alleles render mutant plants sterile by causing an unusual cell-cycle arrest in anaphase II that is characterized by delayed chromosome decondensation and aberrant rearrangement of the meiotic spindle. Disruption of SMG7 causes embryonic lethality.; SMG7; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: meiosis, spindle assembly involved in meiosis, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Telomerase activating protein Est1 (InterPro:IPR019458); BEST Arabidopsis thaliana protein match is: Telomerase activating protein Est1 (TAIR:AT1G28260.2). & (reliability: 282.0) & (original description: no original description)


Gene families : OG_42_0003131 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003131_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00001085-RA
Cluster HCCA clusters: Cluster_99

Target Alias Description ECC score Gene Family Method Actions
GRMZM2G352959 No alias Telomerase activating protein Est1 0.02 Orthogroups_2024-Update
PSME_00010693-RA No alias (at5g19400 : 134.0) Encodes SMG7, a protein that... 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source
MF GO:0003700 DNA-binding transcription factor activity IEP Predicted GO
MF GO:0140110 transcription regulator activity IEP Predicted GO
InterPro domains Description Start Stop
IPR019458 EST1 73 199
No external refs found!