PSME_00001195-RA


Description : (o49914|mloh1_orysa : 296.0) MLO protein homolog 1 (OsMLO1) - Oryza sativa (Rice) & (at1g11310 : 293.0) A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO2 belongs to the clade IV, with AtMLO3, AtMLO6 and AtMLO12. The gene is expressed during early seedling growth, in roots, in vascular system of cotyledons and young leaves,and in fruit abscission zone; it was not expressed in anthers and pollen, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s). mlo resistance in A. thaliana does not involve the signaling molecules ethylene, jasmonic acid or salicylic acid, but requires a syntaxin, glycosyl hydrolase and ABC transporter.; MILDEW RESISTANCE LOCUS O 2 (MLO2); FUNCTIONS IN: calmodulin binding; INVOLVED IN: defense response to fungus, incompatible interaction, cell death, response to fungus, negative regulation of defense response, defense response; LOCATED IN: plasma membrane; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT1G61560.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 586.0) & (original description: no original description)


Gene families : OG_42_0000124 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000124_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00001195-RA
Cluster HCCA clusters: Cluster_91

Target Alias Description ECC score Gene Family Method Actions
Bradi4g23887 No alias Seven transmembrane MLO family protein 0.03 Orthogroups_2024-Update
Glyma.08G188600 No alias Seven transmembrane MLO family protein 0.02 Orthogroups_2024-Update
Glyma.12G119300 No alias Seven transmembrane MLO family protein 0.05 Orthogroups_2024-Update
HORVU6Hr1G076080.1 No alias Unknown function 0.02 Orthogroups_2024-Update
MA_10305178g0010 No alias (at1g11000 : 176.0) A member of a large family of... 0.04 Orthogroups_2024-Update
Seita.5G407800.1 No alias Unknown function 0.03 Orthogroups_2024-Update
Solyc03g095650 No alias MLO-like protein (AHRD V3.3 *** K4BIY8_SOLLC) 0.04 Orthogroups_2024-Update

Type GO Term Name Evidence Source
BP GO:0006952 defense response IEA InterProScan predictions
CC GO:0016021 integral component of membrane IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0003774 motor activity IEP Predicted GO
MF GO:0003777 microtubule motor activity IEP Predicted GO
MF GO:0003950 NAD+ ADP-ribosyltransferase activity IEP Predicted GO
MF GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds IEP Predicted GO
MF GO:0004888 transmembrane signaling receptor activity IEP Predicted GO
MF GO:0004970 ionotropic glutamate receptor activity IEP Predicted GO
MF GO:0005215 transporter activity IEP Predicted GO
MF GO:0005216 ion channel activity IEP Predicted GO
MF GO:0005230 extracellular ligand-gated ion channel activity IEP Predicted GO
BP GO:0005975 carbohydrate metabolic process IEP Predicted GO
BP GO:0006471 protein ADP-ribosylation IEP Predicted GO
BP GO:0006928 movement of cell or subcellular component IEP Predicted GO
BP GO:0007017 microtubule-based process IEP Predicted GO
BP GO:0007018 microtubule-based movement IEP Predicted GO
MF GO:0008017 microtubule binding IEP Predicted GO
MF GO:0008066 glutamate receptor activity IEP Predicted GO
MF GO:0008092 cytoskeletal protein binding IEP Predicted GO
MF GO:0015075 ion transmembrane transporter activity IEP Predicted GO
MF GO:0015267 channel activity IEP Predicted GO
MF GO:0015276 ligand-gated ion channel activity IEP Predicted GO
MF GO:0015318 inorganic molecular entity transmembrane transporter activity IEP Predicted GO
MF GO:0015631 tubulin binding IEP Predicted GO
CC GO:0016020 membrane IEP Predicted GO
MF GO:0016763 transferase activity, transferring pentosyl groups IEP Predicted GO
MF GO:0016798 hydrolase activity, acting on glycosyl bonds IEP Predicted GO
MF GO:0022803 passive transmembrane transporter activity IEP Predicted GO
MF GO:0022824 transmitter-gated ion channel activity IEP Predicted GO
MF GO:0022834 ligand-gated channel activity IEP Predicted GO
MF GO:0022835 transmitter-gated channel activity IEP Predicted GO
MF GO:0022836 gated channel activity IEP Predicted GO
MF GO:0022838 substrate-specific channel activity IEP Predicted GO
MF GO:0022839 ion gated channel activity IEP Predicted GO
MF GO:0022857 transmembrane transporter activity IEP Predicted GO
MF GO:0030594 neurotransmitter receptor activity IEP Predicted GO
MF GO:0038023 signaling receptor activity IEP Predicted GO
MF GO:0060089 molecular transducer activity IEP Predicted GO
InterPro domains Description Start Stop
IPR004326 Mlo 50 378
No external refs found!