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- PSME_00001195-RA
PSME_00001195-RA
Description : (o49914|mloh1_orysa : 296.0) MLO protein homolog 1 (OsMLO1) - Oryza sativa (Rice) & (at1g11310 : 293.0) A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO2 belongs to the clade IV, with AtMLO3, AtMLO6 and AtMLO12. The gene is expressed during early seedling growth, in roots, in vascular system of cotyledons and young leaves,and in fruit abscission zone; it was not expressed in anthers and pollen, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s). mlo resistance in A. thaliana does not involve the signaling molecules ethylene, jasmonic acid or salicylic acid, but requires a syntaxin, glycosyl hydrolase and ABC transporter.; MILDEW RESISTANCE LOCUS O 2 (MLO2); FUNCTIONS IN: calmodulin binding; INVOLVED IN: defense response to fungus, incompatible interaction, cell death, response to fungus, negative regulation of defense response, defense response; LOCATED IN: plasma membrane; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT1G61560.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 586.0) & (original description: no original description)
Expression Profile
Attention: This gene has low abundance.
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Co-expression Networks
Type | Description | Actions |
Neighborhood | Pseudotsuga release: PSME_00001195-RA | |
Cluster | HCCA clusters: Cluster_91 | |
Expression Context Conservation (ECC)
Target | Alias | Description | ECC score | Gene Family Method | Actions |
Bradi4g23887 | No alias | Seven transmembrane MLO family protein | 0.03 | Orthogroups_2024-Update | |
Glyma.08G188600 | No alias | Seven transmembrane MLO family protein | 0.02 | Orthogroups_2024-Update | |
Glyma.12G119300 | No alias | Seven transmembrane MLO family protein | 0.05 | Orthogroups_2024-Update | |
HORVU6Hr1G076080.1 | No alias | Unknown function | 0.02 | Orthogroups_2024-Update | |
MA_10305178g0010 | No alias | (at1g11000 : 176.0) A member of a large family of... | 0.04 | Orthogroups_2024-Update | |
Seita.5G407800.1 | No alias | Unknown function | 0.03 | Orthogroups_2024-Update | |
Solyc03g095650 | No alias | MLO-like protein (AHRD V3.3 *** K4BIY8_SOLLC) | 0.04 | Orthogroups_2024-Update | |
Functional Annotation
Type | GO Term | Name | Evidence | Source |
CC | GO:0005575 | cellular_component | None | Extended |
BP | GO:0006950 | response to stress | None | Extended |
BP | GO:0006952 | defense response | IEA | InterProScan predictions |
BP | GO:0008150 | biological_process | None | Extended |
CC | GO:0016021 | integral component of membrane | IEA | InterProScan predictions |
CC | GO:0031224 | intrinsic component of membrane | None | Extended |
CC | GO:0044425 | membrane part | None | Extended |
BP | GO:0050896 | response to stimulus | None | Extended |
Type | GO Term | Name | Evidence | Source |
MF | GO:0003774 | motor activity | IEP | Predicted GO |
MF | GO:0003777 | microtubule motor activity | IEP | Predicted GO |
MF | GO:0003950 | NAD+ ADP-ribosyltransferase activity | IEP | Predicted GO |
MF | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds | IEP | Predicted GO |
MF | GO:0004888 | transmembrane signaling receptor activity | IEP | Predicted GO |
MF | GO:0004970 | ionotropic glutamate receptor activity | IEP | Predicted GO |
MF | GO:0005215 | transporter activity | IEP | Predicted GO |
MF | GO:0005216 | ion channel activity | IEP | Predicted GO |
MF | GO:0005230 | extracellular ligand-gated ion channel activity | IEP | Predicted GO |
BP | GO:0005975 | carbohydrate metabolic process | IEP | Predicted GO |
BP | GO:0006471 | protein ADP-ribosylation | IEP | Predicted GO |
BP | GO:0006928 | movement of cell or subcellular component | IEP | Predicted GO |
BP | GO:0007017 | microtubule-based process | IEP | Predicted GO |
BP | GO:0007018 | microtubule-based movement | IEP | Predicted GO |
MF | GO:0008017 | microtubule binding | IEP | Predicted GO |
MF | GO:0008066 | glutamate receptor activity | IEP | Predicted GO |
MF | GO:0008092 | cytoskeletal protein binding | IEP | Predicted GO |
MF | GO:0015075 | ion transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0015267 | channel activity | IEP | Predicted GO |
MF | GO:0015276 | ligand-gated ion channel activity | IEP | Predicted GO |
MF | GO:0015318 | inorganic molecular entity transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0015631 | tubulin binding | IEP | Predicted GO |
CC | GO:0016020 | membrane | IEP | Predicted GO |
MF | GO:0016763 | transferase activity, transferring pentosyl groups | IEP | Predicted GO |
MF | GO:0016798 | hydrolase activity, acting on glycosyl bonds | IEP | Predicted GO |
MF | GO:0022803 | passive transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0022824 | transmitter-gated ion channel activity | IEP | Predicted GO |
MF | GO:0022834 | ligand-gated channel activity | IEP | Predicted GO |
MF | GO:0022835 | transmitter-gated channel activity | IEP | Predicted GO |
MF | GO:0022836 | gated channel activity | IEP | Predicted GO |
MF | GO:0022838 | substrate-specific channel activity | IEP | Predicted GO |
MF | GO:0022839 | ion gated channel activity | IEP | Predicted GO |
MF | GO:0022857 | transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0030594 | neurotransmitter receptor activity | IEP | Predicted GO |
MF | GO:0038023 | signaling receptor activity | IEP | Predicted GO |
MF | GO:0060089 | molecular transducer activity | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
IPR004326 | Mlo | 50 | 378 |