PSME_00001607-RA

Description : (at5g04620 : 127.0) The cDNA encoding 7-keto-8-aminopelargonic acid (KAPA) synthase, the first committed enzyme of the biotin synthesis pathway has been cloned and its molecular function confirmed (functional complementation of an E. coli mutant). The subcellular localization of the enzyme (cytosol) proves that the biotin biosynthesis in plants takes place in different compartments which differs from the biosynthetic route found in microorganisms.; biotin F (BIOF); CONTAINS InterPro DOMAIN/s: Aminotransferase, class I/classII (InterPro:IPR004839), Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421); BEST Arabidopsis thaliana protein match is: long chain base2 (TAIR:AT5G23670.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 254.0) & (original description: no original description)

Gene families : OG_42_0004149 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004149_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pseudotsuga release: PSME_00001607-RA
Cluster	HCCA clusters: Cluster_626

Target	Alias	Description	ECC score	Gene Family Method	Actions
Brara.J02723.1	No alias	7-keto-8-aminopelargonic acid (KAPA) synthase & EC_2.3...	0.03	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	IEA	InterProScan predictions
MF	GO:0019842	vitamin binding	None	Extended
MF	GO:0030170	pyridoxal phosphate binding	IEA	InterProScan predictions
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0048037	cofactor binding	None	Extended
MF	GO:0050662	coenzyme binding	None	Extended
MF	GO:0070279	vitamin B6 binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000272	polysaccharide catabolic process	IEP	Predicted GO
MF	GO:0004017	adenylate kinase activity	IEP	Predicted GO
MF	GO:0004312	fatty acid synthase activity	IEP	Predicted GO
MF	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity	IEP	Predicted GO
BP	GO:0006631	fatty acid metabolic process	IEP	Predicted GO
BP	GO:0006633	fatty acid biosynthetic process	IEP	Predicted GO
BP	GO:0016052	carbohydrate catabolic process	IEP	Predicted GO
MF	GO:0016160	amylase activity	IEP	Predicted GO
MF	GO:0016161	beta-amylase activity	IEP	Predicted GO
MF	GO:0016776	phosphotransferase activity, phosphate group as acceptor	IEP	Predicted GO
MF	GO:0019205	nucleobase-containing compound kinase activity	IEP	Predicted GO
MF	GO:0050145	nucleoside monophosphate kinase activity	IEP	Predicted GO
BP	GO:0072330	monocarboxylic acid biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR004839	Aminotransferase_I/II	3	76

External Links

No external refs found!

PSME_00001607-RA

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation