PSME_00002336-RA

Description : (p48534|apx1_pea : 290.0) L-ascorbate peroxidase, cytosolic (EC 1.11.1.11) (AP) (PsAPx01) - Pisum sativum (Garden pea) & (at1g07890 : 279.0) Encodes a cytosolic ascorbate peroxidase APX1. Ascorbate peroxidases are enzymes that scavenge hydrogen peroxide in plant cells. Eight types of APX have been described for Arabidopsis: three cytosolic (APX1, APX2, APX6), two chloroplastic types (stromal sAPX, thylakoid tAPX), and three microsomal (APX3, APX4, APX5) isoforms. At least part of the induction of heat shock proteins during light stress in Arabidopsis is mediated by H2O2 that is scavenged by APX1. Expression of the gene is downregulated in the presence of paraquat, an inducer of photoxidative stress.; ascorbate peroxidase 1 (APX1); FUNCTIONS IN: L-ascorbate peroxidase activity; INVOLVED IN: response to reactive oxygen species, response to salt stress, response to heat, hydrogen peroxide catabolic process, embryo development ending in seed dormancy; LOCATED IN: cytosol, chloroplast, plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Haem peroxidase (InterPro:IPR010255), Plant ascorbate peroxidase (InterPro:IPR002207), Peroxidases heam-ligand binding site (InterPro:IPR019793), Haem peroxidase, plant/fungal/bacterial (InterPro:IPR002016), Peroxidase, active site (InterPro:IPR019794); BEST Arabidopsis thaliana protein match is: ascorbate peroxidase 2 (TAIR:AT3G09640.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 558.0) & (original description: no original description)

Gene families : OG_42_0000926 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000926_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pseudotsuga release: PSME_00002336-RA
Cluster	HCCA clusters: Cluster_185

Target	Alias	Description	ECC score	Gene Family Method
270176	No alias	ascorbate peroxidase 1	0.04	Orthogroups_2024-Update
HORVU6Hr1G088460.1	No alias	EC_1.11 oxidoreductase acting on peroxide as acceptor	0.03	Orthogroups_2024-Update
Potri.009G015400	No alias	ascorbate peroxidase 1	0.03	Orthogroups_2024-Update
Seita.2G444000.1	No alias	EC_1.11 oxidoreductase acting on peroxide as acceptor &...	0.05	Orthogroups_2024-Update
Sopen06g001140	No alias	Peroxidase	0.06	Orthogroups_2024-Update
Sopen06g001150	No alias	Peroxidase	0.04	Orthogroups_2024-Update
evm.model.contig_2083.12	No alias	(at4g35000 : 262.0) Encodes a microsomal ascorbate...	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004601	peroxidase activity	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006979	response to oxidative stress	IEA	InterProScan predictions
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0016209	antioxidant activity	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	None	Extended
MF	GO:0020037	heme binding	IEA	InterProScan predictions
MF	GO:0046906	tetrapyrrole binding	None	Extended
MF	GO:0048037	cofactor binding	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0055114	oxidation-reduction process	IEA	InterProScan predictions
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003676	nucleic acid binding	IEP	Predicted GO
MF	GO:0003678	DNA helicase activity	IEP	Predicted GO
MF	GO:0003848	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity	IEP	Predicted GO
MF	GO:0004386	helicase activity	IEP	Predicted GO
MF	GO:0004620	phospholipase activity	IEP	Predicted GO
MF	GO:0005048	signal sequence binding	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
CC	GO:0005759	mitochondrial matrix	IEP	Predicted GO
BP	GO:0006457	protein folding	IEP	Predicted GO
BP	GO:0006479	protein methylation	IEP	Predicted GO
BP	GO:0006621	protein retention in ER lumen	IEP	Predicted GO
BP	GO:0006760	folic acid-containing compound metabolic process	IEP	Predicted GO
BP	GO:0007049	cell cycle	IEP	Predicted GO
MF	GO:0008170	N-methyltransferase activity	IEP	Predicted GO
BP	GO:0008213	protein alkylation	IEP	Predicted GO
MF	GO:0008270	zinc ion binding	IEP	Predicted GO
MF	GO:0008276	protein methyltransferase activity	IEP	Predicted GO
BP	GO:0009396	folic acid-containing compound biosynthetic process	IEP	Predicted GO
MF	GO:0016278	lysine N-methyltransferase activity	IEP	Predicted GO
MF	GO:0016279	protein-lysine N-methyltransferase activity	IEP	Predicted GO
MF	GO:0016298	lipase activity	IEP	Predicted GO
MF	GO:0016307	phosphatidylinositol phosphate kinase activity	IEP	Predicted GO
BP	GO:0016571	histone methylation	IEP	Predicted GO
MF	GO:0016778	diphosphotransferase activity	IEP	Predicted GO
MF	GO:0016854	racemase and epimerase activity	IEP	Predicted GO
MF	GO:0016855	racemase and epimerase activity, acting on amino acids and derivatives	IEP	Predicted GO
BP	GO:0018022	peptidyl-lysine methylation	IEP	Predicted GO
MF	GO:0018024	histone-lysine N-methyltransferase activity	IEP	Predicted GO
BP	GO:0018193	peptidyl-amino acid modification	IEP	Predicted GO
CC	GO:0031974	membrane-enclosed lumen	IEP	Predicted GO
BP	GO:0032507	maintenance of protein location in cell	IEP	Predicted GO
MF	GO:0033218	amide binding	IEP	Predicted GO
BP	GO:0034968	histone lysine methylation	IEP	Predicted GO
BP	GO:0035437	maintenance of protein localization in endoplasmic reticulum	IEP	Predicted GO
MF	GO:0036361	racemase activity, acting on amino acids and derivatives	IEP	Predicted GO
MF	GO:0042054	histone methyltransferase activity	IEP	Predicted GO
MF	GO:0042277	peptide binding	IEP	Predicted GO
MF	GO:0042393	histone binding	IEP	Predicted GO
BP	GO:0042398	cellular modified amino acid biosynthetic process	IEP	Predicted GO
BP	GO:0042558	pteridine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0042559	pteridine-containing compound biosynthetic process	IEP	Predicted GO
CC	GO:0043233	organelle lumen	IEP	Predicted GO
BP	GO:0043414	macromolecule methylation	IEP	Predicted GO
CC	GO:0044429	mitochondrial part	IEP	Predicted GO
BP	GO:0045185	maintenance of protein location	IEP	Predicted GO
MF	GO:0046923	ER retention sequence binding	IEP	Predicted GO
MF	GO:0050290	sphingomyelin phosphodiesterase D activity	IEP	Predicted GO
MF	GO:0051082	unfolded protein binding	IEP	Predicted GO
BP	GO:0051235	maintenance of location	IEP	Predicted GO
BP	GO:0051321	meiotic cell cycle	IEP	Predicted GO
BP	GO:0051651	maintenance of location in cell	IEP	Predicted GO
CC	GO:0070013	intracellular organelle lumen	IEP	Predicted GO
BP	GO:0072595	maintenance of protein localization in organelle	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR002016	Haem_peroxidase_pln/fun/bac	141	186
IPR002016	Haem_peroxidase_pln/fun/bac	27	134

External Links

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PSME_00002336-RA

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation