PSME_00002410-RA

Description : (at4g34350 : 655.0) Arabidopsis ISPH is involved in the plastid nonmevalonate pathway of isoprenoid biosynthesis. It was shown to complement the lethal phenotype of E. coli ispH mutant and is therefore most likely encodes a protein with 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity involved in the last step of mevalonate-independent isopentenyl biosynthesis. Mutant has Albino seedling.; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase (HDR); FUNCTIONS IN: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity, 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity; INVOLVED IN: response to antibiotic, isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway; LOCATED IN: chloroplast stroma, chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: LytB protein (InterPro:IPR003451); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 1310.0) & (original description: no original description)

Gene families : OG_42_0004636 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004636_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pseudotsuga release: PSME_00002410-RA
Cluster	HCCA clusters: Cluster_96

Target	Alias	Description	ECC score	Gene Family Method
A4A49_21630	No alias	4-hydroxy-3-methylbut-2-enyl diphosphate reductase, chloroplastic	0.02	Orthogroups_2024-Update
Mp5g09880.1	No alias	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	0.02	Orthogroups_2024-Update
Sopen01g051490	No alias	LytB protein	0.03	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
BP	GO:0006081	cellular aldehyde metabolic process	None	Extended
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006090	pyruvate metabolic process	None	Extended
BP	GO:0006629	lipid metabolic process	None	Extended
BP	GO:0006644	phospholipid metabolic process	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008610	lipid biosynthetic process	None	Extended
BP	GO:0008654	phospholipid biosynthetic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009240	isopentenyl diphosphate biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	None	Extended
MF	GO:0016726	oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor	None	Extended
BP	GO:0019288	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	IEA	InterProScan predictions
BP	GO:0019637	organophosphate metabolic process	None	Extended
BP	GO:0019682	glyceraldehyde-3-phosphate metabolic process	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
BP	GO:0032787	monocarboxylic acid metabolic process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044255	cellular lipid metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046490	isopentenyl diphosphate metabolic process	None	Extended
MF	GO:0046872	metal ion binding	IEA	InterProScan predictions
BP	GO:0050992	dimethylallyl diphosphate biosynthetic process	IEA	InterProScan predictions
BP	GO:0050993	dimethylallyl diphosphate metabolic process	None	Extended
MF	GO:0051745	4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity	IEA	InterProScan predictions
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090407	organophosphate biosynthetic process	None	Extended
BP	GO:1901135	carbohydrate derivative metabolic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000287	magnesium ion binding	IEP	Predicted GO
MF	GO:0004743	pyruvate kinase activity	IEP	Predicted GO
CC	GO:0005576	extracellular region	IEP	Predicted GO
CC	GO:0005618	cell wall	IEP	Predicted GO
BP	GO:0005975	carbohydrate metabolic process	IEP	Predicted GO
BP	GO:0005976	polysaccharide metabolic process	IEP	Predicted GO
BP	GO:0006073	cellular glucan metabolic process	IEP	Predicted GO
BP	GO:0006720	isoprenoid metabolic process	IEP	Predicted GO
BP	GO:0006721	terpenoid metabolic process	IEP	Predicted GO
MF	GO:0008168	methyltransferase activity	IEP	Predicted GO
MF	GO:0008171	O-methyltransferase activity	IEP	Predicted GO
BP	GO:0008299	isoprenoid biosynthetic process	IEP	Predicted GO
MF	GO:0008661	1-deoxy-D-xylulose-5-phosphate synthase activity	IEP	Predicted GO
MF	GO:0008685	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity	IEP	Predicted GO
BP	GO:0016114	terpenoid biosynthetic process	IEP	Predicted GO
MF	GO:0016740	transferase activity	IEP	Predicted GO
MF	GO:0016741	transferase activity, transferring one-carbon groups	IEP	Predicted GO
MF	GO:0016744	transferase activity, transferring aldehyde or ketonic groups	IEP	Predicted GO
MF	GO:0016757	transferase activity, transferring glycosyl groups	IEP	Predicted GO
MF	GO:0016762	xyloglucan:xyloglucosyl transferase activity	IEP	Predicted GO
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	IEP	Predicted GO
MF	GO:0016829	lyase activity	IEP	Predicted GO
MF	GO:0016849	phosphorus-oxygen lyase activity	IEP	Predicted GO
CC	GO:0030312	external encapsulating structure	IEP	Predicted GO
MF	GO:0030955	potassium ion binding	IEP	Predicted GO
MF	GO:0031420	alkali metal ion binding	IEP	Predicted GO
BP	GO:0044042	glucan metabolic process	IEP	Predicted GO
BP	GO:0044262	cellular carbohydrate metabolic process	IEP	Predicted GO
BP	GO:0044264	cellular polysaccharide metabolic process	IEP	Predicted GO
MF	GO:0046527	glucosyltransferase activity	IEP	Predicted GO
MF	GO:0046983	protein dimerization activity	IEP	Predicted GO
CC	GO:0048046	apoplast	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR003451	LytB/IspH	133	490

External Links

No external refs found!

PSME_00002410-RA

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation