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  5. PSME_00002556-RA

PSME_00002556-RA


Description : (at1g63440 : 558.0) The Arabidopsis P-type ATPase HMA5 is involved in Cu detoxification. hma5 mutant plants exhibit Cu hypersensitivity, which is especially dramatic in roots where HMA5 is mostly expressed.; heavy metal atpase 5 (HMA5); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; INVOLVED IN: detoxification of copper ion, response to copper ion; LOCATED IN: integral to membrane, membrane; EXPRESSED IN: 8 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Heavy metal transport/detoxification protein (InterPro:IPR006121), ATPase, P type, cation/copper-transporter (InterPro:IPR006403), ATPase, P-type, ATPase-associated domain (InterPro:IPR008250), Heavy-metal-associated, conserved site (InterPro:IPR017969), Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (InterPro:IPR001757), ATPase, P-type, heavy metal translocating (InterPro:IPR006416), ATPase, P-type phosphorylation site (InterPro:IPR018303); BEST Arabidopsis thaliana protein match is: copper-exporting ATPase / responsive-to-antagonist 1 / copper-transporting ATPase (RAN1) (TAIR:AT5G44790.1); Has 47061 Blast hits to 34034 proteins in 3459 species: Archae - 1020; Bacteria - 31793; Metazoa - 4958; Fungi - 2589; Plants - 1873; Viruses - 3; Other Eukaryotes - 4825 (source: NCBI BLink). & (q2qmx9|aca1_orysa : 96.7) Calcium-transporting ATPase 1, plasma membrane-type (EC 3.6.3.8) (Ca(2+)-ATPase isoform 1) (Plastid envelope ATPase 1) - Oryza sativa (Rice) & (reliability: 1116.0) & (original description: no original description)


Gene families : OG_42_0000805 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000805_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00002556-RA
Cluster HCCA clusters: Cluster_43


Type GO Term Name Evidence Source
BP GO:0030001 metal ion transport IEA InterProScan predictions
MF GO:0046872 metal ion binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0000049 tRNA binding IEP Predicted GO
MF GO:0003779 actin binding IEP Predicted GO
MF GO:0004672 protein kinase activity IEP Predicted GO
MF GO:0004866 endopeptidase inhibitor activity IEP Predicted GO
MF GO:0004869 cysteine-type endopeptidase inhibitor activity IEP Predicted GO
MF GO:0004888 transmembrane signaling receptor activity IEP Predicted GO
MF GO:0004970 ionotropic glutamate receptor activity IEP Predicted GO
MF GO:0005216 ion channel activity IEP Predicted GO
MF GO:0005230 extracellular ligand-gated ion channel activity IEP Predicted GO
MF GO:0005515 protein binding IEP Predicted GO
BP GO:0006355 regulation of transcription, DNA-templated IEP Predicted GO
BP GO:0006464 cellular protein modification process IEP Predicted GO
BP GO:0006468 protein phosphorylation IEP Predicted GO
BP GO:0006793 phosphorus metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
BP GO:0007010 cytoskeleton organization IEP Predicted GO
MF GO:0008066 glutamate receptor activity IEP Predicted GO
BP GO:0009889 regulation of biosynthetic process IEP Predicted GO
BP GO:0010468 regulation of gene expression IEP Predicted GO
BP GO:0010556 regulation of macromolecule biosynthetic process IEP Predicted GO
MF GO:0015276 ligand-gated ion channel activity IEP Predicted GO
MF GO:0016301 kinase activity IEP Predicted GO
BP GO:0016310 phosphorylation IEP Predicted GO
MF GO:0016740 transferase activity IEP Predicted GO
MF GO:0016772 transferase activity, transferring phosphorus-containing groups IEP Predicted GO
MF GO:0016773 phosphotransferase activity, alcohol group as acceptor IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
BP GO:0019219 regulation of nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0019725 cellular homeostasis IEP Predicted GO
MF GO:0022824 transmitter-gated ion channel activity IEP Predicted GO
MF GO:0022834 ligand-gated channel activity IEP Predicted GO
MF GO:0022835 transmitter-gated channel activity IEP Predicted GO
MF GO:0022836 gated channel activity IEP Predicted GO
MF GO:0022838 substrate-specific channel activity IEP Predicted GO
MF GO:0022839 ion gated channel activity IEP Predicted GO
MF GO:0030414 peptidase inhibitor activity IEP Predicted GO
MF GO:0030594 neurotransmitter receptor activity IEP Predicted GO
BP GO:0031326 regulation of cellular biosynthetic process IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
BP GO:0036211 protein modification process IEP Predicted GO
MF GO:0038023 signaling receptor activity IEP Predicted GO
BP GO:0042592 homeostatic process IEP Predicted GO
BP GO:0043412 macromolecule modification IEP Predicted GO
MF GO:0043531 ADP binding IEP Predicted GO
BP GO:0044260 cellular macromolecule metabolic process IEP Predicted GO
BP GO:0044267 cellular protein metabolic process IEP Predicted GO
BP GO:0045454 cell redox homeostasis IEP Predicted GO
BP GO:0050789 regulation of biological process IEP Predicted GO
BP GO:0050794 regulation of cellular process IEP Predicted GO
BP GO:0051252 regulation of RNA metabolic process IEP Predicted GO
MF GO:0060089 molecular transducer activity IEP Predicted GO
MF GO:0061134 peptidase regulator activity IEP Predicted GO
MF GO:0061135 endopeptidase regulator activity IEP Predicted GO
BP GO:0065007 biological regulation IEP Predicted GO
BP GO:0065008 regulation of biological quality IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
MF GO:0140096 catalytic activity, acting on a protein IEP Predicted GO
BP GO:1903506 regulation of nucleic acid-templated transcription IEP Predicted GO
BP GO:2000112 regulation of cellular macromolecule biosynthetic process IEP Predicted GO
BP GO:2001141 regulation of RNA biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR006121 HMA_dom 58 118
IPR006121 HMA_dom 136 195
No external refs found!