PSME_00003012-RA

Description : (at2g34660 : 1782.0) encodes a multidrug resistance-associated protein that is MgATP-energized glutathione S-conjugate pump. The expression of this gene is upregulated by herbicide safeners such as benoxacor and fenclorim.; multidrug resistance-associated protein 2 (MRP2); CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: multidrug resistance-associated protein 1 (TAIR:AT1G30400.2). & (q6yuu5|mdr_orysa : 198.0) Putative multidrug resistance protein (P-glycoprotein) - Oryza sativa (Rice) & (reliability: 3564.0) & (original description: no original description)

Gene families : OG_42_0000076 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000076_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pseudotsuga release: PSME_00003012-RA
Cluster	HCCA clusters: Cluster_232

Target	Alias	Description	ECC score	Gene Family Method
144775	No alias	multidrug resistance-associated protein 5	0.03	Orthogroups_2024-Update
145432	No alias	multidrug resistance-associated protein 6	0.02	Orthogroups_2024-Update
402326	No alias	multidrug resistance-associated protein 5	0.02	Orthogroups_2024-Update
Cre17.g734612	No alias	multidrug resistance-associated protein 2	0.02	Orthogroups_2024-Update
HORVU7Hr1G025000.3	No alias	subfamily ABCC transporter	0.02	Orthogroups_2024-Update
LOC_Os06g06440	No alias	ABC transporter, ATP-binding protein, putative, expressed	0.02	Orthogroups_2024-Update
Mp5g02230.1	No alias	subfamily ABCC transporter	0.02	Orthogroups_2024-Update
Mp7g13400.1	No alias	subfamily ABCC transporter	0.02	Orthogroups_2024-Update
PSME_00045048-RA	No alias	(at2g47800 : 243.0) Encodes a plasma membrane localized...	0.01	Orthogroups_2024-Update
Pp1s122_170V6	No alias	multidrug resistance protein abc transporter family	0.02	Orthogroups_2024-Update
Pp1s223_76V6	No alias	multidrug resistance protein abc transporter family	0.02	Orthogroups_2024-Update
Pp1s224_120V6	No alias	multidrug resistance protein abc transporter family	0.02	Orthogroups_2024-Update
Seita.4G047900.1	No alias	subfamily ABCC transporter	0.02	Orthogroups_2024-Update
Sobic.010G169000.1	No alias	subfamily ABCC transporter	0.02	Orthogroups_2024-Update
Solyc03g117540	No alias	ABC transporter family protein (AHRD V3.3 - A0A097P9P6_HEVBR)	0.02	Orthogroups_2024-Update
Sopen08g002840	No alias	ABC transporter transmembrane region	0.02	Orthogroups_2024-Update
Sopen12g023190	No alias	ABC transporter	0.02	Orthogroups_2024-Update
evm.model.tig00020553.191	No alias	(at1g30420 : 191.0) member of MRP subfamily; multidrug...	0.01	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005215	transporter activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
MF	GO:0015399	primary active transmembrane transporter activity	None	Extended
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	None	Extended
CC	GO:0016021	integral component of membrane	IEA	InterProScan predictions
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	IEA	InterProScan predictions
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0022804	active transmembrane transporter activity	None	Extended
MF	GO:0022857	transmembrane transporter activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IEA	InterProScan predictions
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0043492	ATPase activity, coupled to movement of substances	None	Extended
CC	GO:0044425	membrane part	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0055085	transmembrane transport	IEA	InterProScan predictions
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003682	chromatin binding	IEP	Predicted GO
MF	GO:0003997	acyl-CoA oxidase activity	IEP	Predicted GO
MF	GO:0004177	aminopeptidase activity	IEP	Predicted GO
MF	GO:0004197	cysteine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004198	calcium-dependent cysteine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004347	glucose-6-phosphate isomerase activity	IEP	Predicted GO
MF	GO:0004455	ketol-acid reductoisomerase activity	IEP	Predicted GO
MF	GO:0004751	ribose-5-phosphate isomerase activity	IEP	Predicted GO
MF	GO:0005509	calcium ion binding	IEP	Predicted GO
MF	GO:0005544	calcium-dependent phospholipid binding	IEP	Predicted GO
CC	GO:0005777	peroxisome	IEP	Predicted GO
BP	GO:0006081	cellular aldehyde metabolic process	IEP	Predicted GO
BP	GO:0006082	organic acid metabolic process	IEP	Predicted GO
BP	GO:0006338	chromatin remodeling	IEP	Predicted GO
BP	GO:0006635	fatty acid beta-oxidation	IEP	Predicted GO
MF	GO:0008483	transaminase activity	IEP	Predicted GO
BP	GO:0009052	pentose-phosphate shunt, non-oxidative branch	IEP	Predicted GO
BP	GO:0009062	fatty acid catabolic process	IEP	Predicted GO
BP	GO:0009081	branched-chain amino acid metabolic process	IEP	Predicted GO
BP	GO:0009082	branched-chain amino acid biosynthetic process	IEP	Predicted GO
BP	GO:0016042	lipid catabolic process	IEP	Predicted GO
BP	GO:0016054	organic acid catabolic process	IEP	Predicted GO
BP	GO:0016197	endosomal transport	IEP	Predicted GO
BP	GO:0016482	cytosolic transport	IEP	Predicted GO
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	IEP	Predicted GO
MF	GO:0016769	transferase activity, transferring nitrogenous groups	IEP	Predicted GO
MF	GO:0016860	intramolecular oxidoreductase activity	IEP	Predicted GO
MF	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses	IEP	Predicted GO
BP	GO:0019395	fatty acid oxidation	IEP	Predicted GO
BP	GO:0019682	glyceraldehyde-3-phosphate metabolic process	IEP	Predicted GO
BP	GO:0019693	ribose phosphate metabolic process	IEP	Predicted GO
BP	GO:0019752	carboxylic acid metabolic process	IEP	Predicted GO
BP	GO:0030258	lipid modification	IEP	Predicted GO
CC	GO:0030906	retromer, cargo-selective complex	IEP	Predicted GO
MF	GO:0030976	thiamine pyrophosphate binding	IEP	Predicted GO
MF	GO:0031491	nucleosome binding	IEP	Predicted GO
BP	GO:0034440	lipid oxidation	IEP	Predicted GO
BP	GO:0042147	retrograde transport, endosome to Golgi	IEP	Predicted GO
CC	GO:0042579	microbody	IEP	Predicted GO
BP	GO:0043044	ATP-dependent chromatin remodeling	IEP	Predicted GO
BP	GO:0043436	oxoacid metabolic process	IEP	Predicted GO
BP	GO:0044242	cellular lipid catabolic process	IEP	Predicted GO
MF	GO:0044877	protein-containing complex binding	IEP	Predicted GO
BP	GO:0046395	carboxylic acid catabolic process	IEP	Predicted GO
MF	GO:0052855	ADP-dependent NAD(P)H-hydrate dehydratase activity	IEP	Predicted GO
BP	GO:0072329	monocarboxylic acid catabolic process	IEP	Predicted GO
MF	GO:1901681	sulfur compound binding	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR003439	ABC_transporter-like	950	1098
IPR011527	ABC1_TM_dom	3	264
IPR011527	ABC1_TM_dom	614	881
IPR003439	ABC_transporter-like	326	461

External Links

No external refs found!

PSME_00003012-RA

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation