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- Pseudotsuga menziesii
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- PSME_00003464-RA
PSME_00003464-RA
Description : (at1g08260 : 1385.0) Similar to POL2A, DNA polymerase epsilon catalytic subunit. Essential for Arabidopsis growth. Null homozygotes are embryo lethal, partial loss of function alleles show embryo patterning defects such as root pole displacement. Delayed progression through cell cycle results in embryos with smaller numbers of larger cells.; TILTED 1 (TIL1); FUNCTIONS IN: DNA-directed DNA polymerase activity, DNA binding, nucleotide binding, zinc ion binding, nucleic acid binding; INVOLVED IN: positive regulation of S phase of mitotic cell cycle, negative regulation of long-day photoperiodism, flowering, embryo development ending in seed dormancy; LOCATED IN: apoplast, epsilon DNA polymerase complex; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: DNA polymerase, family B (InterPro:IPR022762), DNA-directed DNA polymerase, family B, exonuclease domain (InterPro:IPR006133), Domain of unknown function DUF1744 (InterPro:IPR013697), Polynucleotidyl transferase, ribonuclease H fold (InterPro:IPR012337), DNA-directed DNA polymerase, family B, conserved region (InterPro:IPR006134); BEST Arabidopsis thaliana protein match is: DNA polymerase epsilon catalytic subunit (TAIR:AT2G27120.1); Has 2011 Blast hits to 1700 proteins in 652 species: Archae - 331; Bacteria - 603; Metazoa - 305; Fungi - 291; Plants - 83; Viruses - 58; Other Eukaryotes - 340 (source: NCBI BLink). & (reliability: 2770.0) & (original description: no original description)
Expression Profile
Attention: This gene has low abundance.
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Co-expression Networks
Type | Description | Actions |
Neighborhood | Pseudotsuga release: PSME_00003464-RA | |
Cluster | HCCA clusters: Cluster_95 | |
Expression Context Conservation (ECC)
Target | Alias | Description | ECC score | Gene Family Method | Actions |
Glyma.12G087000 | No alias | DNA polymerase epsilon catalytic subunit | 0.02 | Orthogroups_2024-Update | |
Solyc11g067110 | No alias | DNA polymerase epsilon catalytic subunit (AHRD V3.3 *-*... | 0.02 | Orthogroups_2024-Update | |
Solyc11g067120 | No alias | No description available | 0.03 | Orthogroups_2024-Update | |
Solyc11g067130 | No alias | No description available | 0.02 | Orthogroups_2024-Update | |
Solyc11g067140 | No alias | DNA polymerase epsilon catalytic subunit A (AHRD V3.3... | 0.02 | Orthogroups_2024-Update | |
Sopen11g026820 | No alias | Domain of unknown function (DUF1744) | 0.02 | Orthogroups_2024-Update | |
Functional Annotation
Type | GO Term | Name | Evidence | Source |
MF | GO:0003674 | molecular_function | None | Extended |
MF | GO:0003824 | catalytic activity | None | Extended |
MF | GO:0003887 | DNA-directed DNA polymerase activity | IEA | InterProScan predictions |
MF | GO:0005488 | binding | None | Extended |
CC | GO:0005575 | cellular_component | None | Extended |
CC | GO:0005634 | nucleus | IEA | InterProScan predictions |
BP | GO:0006139 | nucleobase-containing compound metabolic process | None | Extended |
BP | GO:0006259 | DNA metabolic process | None | Extended |
BP | GO:0006260 | DNA replication | IEA | InterProScan predictions |
BP | GO:0006725 | cellular aromatic compound metabolic process | None | Extended |
BP | GO:0006807 | nitrogen compound metabolic process | None | Extended |
BP | GO:0008150 | biological_process | None | Extended |
BP | GO:0008152 | metabolic process | None | Extended |
MF | GO:0008270 | zinc ion binding | IEA | InterProScan predictions |
BP | GO:0009058 | biosynthetic process | None | Extended |
BP | GO:0009059 | macromolecule biosynthetic process | None | Extended |
BP | GO:0009987 | cellular process | None | Extended |
MF | GO:0016740 | transferase activity | None | Extended |
MF | GO:0016772 | transferase activity, transferring phosphorus-containing groups | None | Extended |
MF | GO:0016779 | nucleotidyltransferase activity | None | Extended |
MF | GO:0034061 | DNA polymerase activity | None | Extended |
BP | GO:0034641 | cellular nitrogen compound metabolic process | None | Extended |
BP | GO:0034645 | cellular macromolecule biosynthetic process | None | Extended |
MF | GO:0043167 | ion binding | None | Extended |
MF | GO:0043169 | cation binding | None | Extended |
BP | GO:0043170 | macromolecule metabolic process | None | Extended |
CC | GO:0043226 | organelle | None | Extended |
CC | GO:0043227 | membrane-bounded organelle | None | Extended |
CC | GO:0043229 | intracellular organelle | None | Extended |
CC | GO:0043231 | intracellular membrane-bounded organelle | None | Extended |
BP | GO:0044237 | cellular metabolic process | None | Extended |
BP | GO:0044238 | primary metabolic process | None | Extended |
BP | GO:0044249 | cellular biosynthetic process | None | Extended |
BP | GO:0044260 | cellular macromolecule metabolic process | None | Extended |
CC | GO:0044424 | intracellular part | None | Extended |
CC | GO:0044464 | cell part | None | Extended |
BP | GO:0046483 | heterocycle metabolic process | None | Extended |
MF | GO:0046872 | metal ion binding | None | Extended |
MF | GO:0046914 | transition metal ion binding | None | Extended |
BP | GO:0071704 | organic substance metabolic process | None | Extended |
BP | GO:0090304 | nucleic acid metabolic process | None | Extended |
MF | GO:0140097 | catalytic activity, acting on DNA | None | Extended |
BP | GO:1901360 | organic cyclic compound metabolic process | None | Extended |
BP | GO:1901576 | organic substance biosynthetic process | None | Extended |
Type | GO Term | Name | Evidence | Source |
MF | GO:0000166 | nucleotide binding | IEP | Predicted GO |
BP | GO:0001510 | RNA methylation | IEP | Predicted GO |
MF | GO:0004175 | endopeptidase activity | IEP | Predicted GO |
MF | GO:0004252 | serine-type endopeptidase activity | IEP | Predicted GO |
CC | GO:0005667 | transcription factor complex | IEP | Predicted GO |
BP | GO:0005991 | trehalose metabolic process | IEP | Predicted GO |
BP | GO:0005992 | trehalose biosynthetic process | IEP | Predicted GO |
BP | GO:0006396 | RNA processing | IEP | Predicted GO |
BP | GO:0006400 | tRNA modification | IEP | Predicted GO |
BP | GO:0006508 | proteolysis | IEP | Predicted GO |
BP | GO:0006855 | drug transmembrane transport | IEP | Predicted GO |
BP | GO:0008033 | tRNA processing | IEP | Predicted GO |
MF | GO:0008081 | phosphoric diester hydrolase activity | IEP | Predicted GO |
MF | GO:0008173 | RNA methyltransferase activity | IEP | Predicted GO |
MF | GO:0008175 | tRNA methyltransferase activity | IEP | Predicted GO |
MF | GO:0008233 | peptidase activity | IEP | Predicted GO |
MF | GO:0008236 | serine-type peptidase activity | IEP | Predicted GO |
MF | GO:0008757 | S-adenosylmethionine-dependent methyltransferase activity | IEP | Predicted GO |
BP | GO:0009312 | oligosaccharide biosynthetic process | IEP | Predicted GO |
BP | GO:0009451 | RNA modification | IEP | Predicted GO |
CC | GO:0009521 | photosystem | IEP | Predicted GO |
CC | GO:0009522 | photosystem I | IEP | Predicted GO |
CC | GO:0009538 | photosystem I reaction center | IEP | Predicted GO |
MF | GO:0015238 | drug transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0015291 | secondary active transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0015297 | antiporter activity | IEP | Predicted GO |
BP | GO:0015893 | drug transport | IEP | Predicted GO |
BP | GO:0015979 | photosynthesis | IEP | Predicted GO |
MF | GO:0016426 | tRNA (adenine) methyltransferase activity | IEP | Predicted GO |
MF | GO:0016429 | tRNA (adenine-N1-)-methyltransferase activity | IEP | Predicted GO |
MF | GO:0017171 | serine hydrolase activity | IEP | Predicted GO |
BP | GO:0030488 | tRNA methylation | IEP | Predicted GO |
CC | GO:0030532 | small nuclear ribonucleoprotein complex | IEP | Predicted GO |
CC | GO:0031515 | tRNA (m1A) methyltransferase complex | IEP | Predicted GO |
BP | GO:0032259 | methylation | IEP | Predicted GO |
MF | GO:0032553 | ribonucleotide binding | IEP | Predicted GO |
CC | GO:0032991 | protein-containing complex | IEP | Predicted GO |
CC | GO:0034708 | methyltransferase complex | IEP | Predicted GO |
MF | GO:0036094 | small molecule binding | IEP | Predicted GO |
MF | GO:0043168 | anion binding | IEP | Predicted GO |
BP | GO:0043414 | macromolecule methylation | IEP | Predicted GO |
CC | GO:0043527 | tRNA methyltransferase complex | IEP | Predicted GO |
CC | GO:0044436 | thylakoid part | IEP | Predicted GO |
BP | GO:0046351 | disaccharide biosynthetic process | IEP | Predicted GO |
CC | GO:0046540 | U4/U6 x U5 tri-snRNP complex | IEP | Predicted GO |
MF | GO:0070011 | peptidase activity, acting on L-amino acid peptides | IEP | Predicted GO |
MF | GO:0070569 | uridylyltransferase activity | IEP | Predicted GO |
MF | GO:0097367 | carbohydrate derivative binding | IEP | Predicted GO |
CC | GO:0097525 | spliceosomal snRNP complex | IEP | Predicted GO |
CC | GO:0097526 | spliceosomal tri-snRNP complex | IEP | Predicted GO |
CC | GO:0098796 | membrane protein complex | IEP | Predicted GO |
CC | GO:0120114 | Sm-like protein family complex | IEP | Predicted GO |
MF | GO:0140096 | catalytic activity, acting on a protein | IEP | Predicted GO |
MF | GO:1901265 | nucleoside phosphate binding | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
IPR013697 | DNA_pol_e_suA_C | 698 | 1066 |