PSME_00004045-RA


Description : (at1g61560 : 478.0) A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO6 belongs to the clade IV, with AtMLO2, AtMLO3 and AtMLO12. The gene is expressed during early seedling growth, in roots and lateral root primordia, in flower and fruit abscission zone, in vascular system of cotyledons, young leaves and petals, in mature rosette leaves, in anthers, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s).; MILDEW RESISTANCE LOCUS O 6 (MLO6); CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT1G11310.1). & (o49914|mloh1_orysa : 436.0) MLO protein homolog 1 (OsMLO1) - Oryza sativa (Rice) & (reliability: 956.0) & (original description: no original description)


Gene families : OG_42_0000124 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000124_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00004045-RA
Cluster HCCA clusters: Cluster_95

Target Alias Description ECC score Gene Family Method Actions
A4A49_00227 No alias mlo-like protein 1 0.03 Orthogroups_2024-Update
Bradi1g76500 No alias Seven transmembrane MLO family protein 0.03 Orthogroups_2024-Update
GRMZM2G416887 No alias Seven transmembrane MLO family protein 0.03 Orthogroups_2024-Update
Glyma.01G165200 No alias Seven transmembrane MLO family protein 0.04 Orthogroups_2024-Update
Glyma.12G223100 No alias Seven transmembrane MLO family protein 0.03 Orthogroups_2024-Update
HORVU0Hr1G008830.1 No alias Unknown function 0.04 Orthogroups_2024-Update
LOC_Os02g35490 No alias MLO domain containing protein, putative, expressed 0.02 Orthogroups_2024-Update
LOC_Os04g36680 No alias MLO domain containing protein, putative, expressed 0.02 Orthogroups_2024-Update
MA_20495g0020 No alias no hits & (original description: no original description) 0.03 Orthogroups_2024-Update
PSME_00016510-RA No alias (at1g61560 : 419.0) A member of a large family of... 0.04 Orthogroups_2024-Update
Solyc10g044510 No alias MLO-like protein (AHRD V3.3 *** K4CZH6_SOLLC) 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
BP GO:0006952 defense response IEA InterProScan predictions
CC GO:0016021 integral component of membrane IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0003700 DNA-binding transcription factor activity IEP Predicted GO
MF GO:0004014 adenosylmethionine decarboxylase activity IEP Predicted GO
MF GO:0004386 helicase activity IEP Predicted GO
MF GO:0004860 protein kinase inhibitor activity IEP Predicted GO
MF GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity IEP Predicted GO
CC GO:0005634 nucleus IEP Predicted GO
CC GO:0005667 transcription factor complex IEP Predicted GO
CC GO:0005672 transcription factor TFIIA complex IEP Predicted GO
BP GO:0006352 DNA-templated transcription, initiation IEP Predicted GO
BP GO:0006355 regulation of transcription, DNA-templated IEP Predicted GO
BP GO:0006367 transcription initiation from RNA polymerase II promoter IEP Predicted GO
BP GO:0006576 cellular biogenic amine metabolic process IEP Predicted GO
BP GO:0006595 polyamine metabolic process IEP Predicted GO
BP GO:0006596 polyamine biosynthetic process IEP Predicted GO
BP GO:0006597 spermine biosynthetic process IEP Predicted GO
BP GO:0006855 drug transmembrane transport IEP Predicted GO
BP GO:0007050 cell cycle arrest IEP Predicted GO
BP GO:0007165 signal transduction IEP Predicted GO
BP GO:0008215 spermine metabolic process IEP Predicted GO
BP GO:0008216 spermidine metabolic process IEP Predicted GO
BP GO:0008295 spermidine biosynthetic process IEP Predicted GO
BP GO:0009058 biosynthetic process IEP Predicted GO
BP GO:0009308 amine metabolic process IEP Predicted GO
BP GO:0009309 amine biosynthetic process IEP Predicted GO
BP GO:0009889 regulation of biosynthetic process IEP Predicted GO
BP GO:0010468 regulation of gene expression IEP Predicted GO
BP GO:0010556 regulation of macromolecule biosynthetic process IEP Predicted GO
MF GO:0015238 drug transmembrane transporter activity IEP Predicted GO
MF GO:0015291 secondary active transmembrane transporter activity IEP Predicted GO
MF GO:0015297 antiporter activity IEP Predicted GO
BP GO:0015893 drug transport IEP Predicted GO
BP GO:0016070 RNA metabolic process IEP Predicted GO
MF GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity IEP Predicted GO
BP GO:0018130 heterocycle biosynthetic process IEP Predicted GO
MF GO:0019207 kinase regulator activity IEP Predicted GO
MF GO:0019210 kinase inhibitor activity IEP Predicted GO
BP GO:0019219 regulation of nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0019222 regulation of metabolic process IEP Predicted GO
BP GO:0019438 aromatic compound biosynthetic process IEP Predicted GO
MF GO:0019887 protein kinase regulator activity IEP Predicted GO
MF GO:0022804 active transmembrane transporter activity IEP Predicted GO
MF GO:0030246 carbohydrate binding IEP Predicted GO
MF GO:0030291 protein serine/threonine kinase inhibitor activity IEP Predicted GO
BP GO:0031323 regulation of cellular metabolic process IEP Predicted GO
BP GO:0031326 regulation of cellular biosynthetic process IEP Predicted GO
BP GO:0032774 RNA biosynthetic process IEP Predicted GO
BP GO:0034654 nucleobase-containing compound biosynthetic process IEP Predicted GO
BP GO:0042401 cellular biogenic amine biosynthetic process IEP Predicted GO
CC GO:0043226 organelle IEP Predicted GO
CC GO:0043227 membrane-bounded organelle IEP Predicted GO
CC GO:0043229 intracellular organelle IEP Predicted GO
CC GO:0043231 intracellular membrane-bounded organelle IEP Predicted GO
BP GO:0044106 cellular amine metabolic process IEP Predicted GO
BP GO:0044271 cellular nitrogen compound biosynthetic process IEP Predicted GO
CC GO:0044451 nucleoplasm part IEP Predicted GO
CC GO:0044798 nuclear transcription factor complex IEP Predicted GO
BP GO:0045786 negative regulation of cell cycle IEP Predicted GO
BP GO:0048523 negative regulation of cellular process IEP Predicted GO
BP GO:0050789 regulation of biological process IEP Predicted GO
BP GO:0050794 regulation of cellular process IEP Predicted GO
BP GO:0051171 regulation of nitrogen compound metabolic process IEP Predicted GO
BP GO:0051252 regulation of RNA metabolic process IEP Predicted GO
BP GO:0051726 regulation of cell cycle IEP Predicted GO
BP GO:0060255 regulation of macromolecule metabolic process IEP Predicted GO
BP GO:0065007 biological regulation IEP Predicted GO
BP GO:0080090 regulation of primary metabolic process IEP Predicted GO
CC GO:0090575 RNA polymerase II transcription factor complex IEP Predicted GO
BP GO:0097164 ammonium ion metabolic process IEP Predicted GO
MF GO:0140110 transcription regulator activity IEP Predicted GO
BP GO:1901362 organic cyclic compound biosynthetic process IEP Predicted GO
BP GO:1901576 organic substance biosynthetic process IEP Predicted GO
BP GO:1903506 regulation of nucleic acid-templated transcription IEP Predicted GO
BP GO:2000112 regulation of cellular macromolecule biosynthetic process IEP Predicted GO
BP GO:2001141 regulation of RNA biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR004326 Mlo 17 527
No external refs found!