PSME_00004490-RA


Description : "(at2g47460 : 180.0) ""MYB12 belongs to subgroup 7 of the R2R3-MYB family. It strongly activates the promoters of chalcone synthase (CHS), flavanone 3-hydroxylase (F3H), flavonol synthase (FLS) and - to a lesser extent - chalcone flavanone isomerase (CHI), but cannot activate the promoters of flavonoid-3'hydroxylase (F3'H) and dihydroflavonol 4-reductase (DF). The activation requires a functional MYB recognition element (MRE). Results from the myb12-1f allele indicate that an activation domain might be present in the C-terminus. Overexpression or knock-out plants do not show any obvious phenotype under greenhouse conditions. Young myb12-ko seedlings contain reduced amounts of flavonoids (quercetin and kaempferol), while seedlings as well as leaves of MYB12-OX plants displayed an increased flavonoid content. They did not show any significant difference in anthocyanin content. Expression of CHS and FLS shows a clear correlation to MYB12 expression levels. CHI and F3H show increased transcript levels in the MYB12-OX lines, but no differences in the knock-out. Even in the absence of functional MYB12, flavonol biosynthesis is not completely absent, suggesting functional redundancy. "" The redundant factors are MYB11 and MYB111 although MYB12 is primarily required for flavonol biosynthesis in roots.; myb domain protein 12 (MYB12); CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287), Myb transcription factor (InterPro:IPR015495); BEST Arabidopsis thaliana protein match is: myb domain protein 11 (TAIR:AT3G62610.1); Has 8833 Blast hits to 8133 proteins in 470 species: Archae - 0; Bacteria - 0; Metazoa - 786; Fungi - 423; Plants - 5965; Viruses - 6; Other Eukaryotes - 1653 (source: NCBI BLink). & (p20026|myb1_horvu : 174.0) Myb-related protein Hv1 - Hordeum vulgare (Barley) & (reliability: 360.0) & (original description: no original description)"


Gene families : OG_42_0000002 (Orthogroups_2024-Update) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00004490-RA
Cluster HCCA clusters: Cluster_112

Target Alias Description ECC score Gene Family Method Actions
A4A49_11142 No alias transcription factor myb30 0.03 Orthogroups_2024-Update
A4A49_20218 No alias transcription factor myb39 0.03 Orthogroups_2024-Update
A4A49_28774 No alias anthocyanin regulatory c1 protein 0.03 Orthogroups_2024-Update
A4A49_33530 No alias transcription factor myb26 0.03 Orthogroups_2024-Update
At2g47190 No alias ATMYB2 [Source:UniProtKB/TrEMBL;Acc:Q39028] 0.03 Orthogroups_2024-Update
At3g13890 No alias Transcription factor MYB26... 0.03 Orthogroups_2024-Update
At5g14340 No alias myb domain protein 40 [Source:TAIR;Acc:AT5G14340] 0.03 Orthogroups_2024-Update
At5g49620 No alias myb domain protein 78 [Source:TAIR;Acc:AT5G49620] 0.04 Orthogroups_2024-Update
Bradi2g62510 No alias myb domain protein 59 0.02 Orthogroups_2024-Update
Bradi5g15246 No alias myb domain protein 79 0.02 Orthogroups_2024-Update
Brara.A01549.1 No alias MYB class-R2R3 subgroup-16 transcription factor &... 0.02 Orthogroups_2024-Update
Brara.B03738.1 No alias Unknown function 0.03 Orthogroups_2024-Update
Brara.C01184.1 No alias MYB class-R2R3 subgroup-14 transcription factor &... 0.02 Orthogroups_2024-Update
Brara.C04156.1 No alias MYB class-R2R3 subgroup-4 transcription factor 0.02 Orthogroups_2024-Update
Brara.D01054.1 No alias MYB class-R2R3 subgroup-15 transcription factor 0.03 Orthogroups_2024-Update
Brara.G02641.1 No alias MYB class-R2R3 transcription factor 0.04 Orthogroups_2024-Update
Brara.G03164.1 No alias MYB class-R2R3 subgroup-1 transcription factor 0.02 Orthogroups_2024-Update
Brara.I01367.1 No alias MYB class-R2R3 transcription factor 0.03 Orthogroups_2024-Update
GRMZM2G001223 No alias myb domain protein 106 0.03 Orthogroups_2024-Update
GRMZM2G013581 No alias myb domain protein 48 0.03 Orthogroups_2024-Update
GRMZM2G123202 No alias myb domain protein 17 0.03 Orthogroups_2024-Update
GRMZM2G143274 No alias myb domain protein 61 0.02 Orthogroups_2024-Update
GRMZM2G162434 No alias myb domain protein 60 0.04 Orthogroups_2024-Update
GRMZM2G176327 No alias myb domain protein 112 0.02 Orthogroups_2024-Update
Glyma.01G196200 No alias myb domain protein 84 0.03 Orthogroups_2024-Update
Glyma.08G031300 No alias myb domain protein 68 0.02 Orthogroups_2024-Update
Glyma.09G032100 No alias myb domain protein 78 0.03 Orthogroups_2024-Update
Glyma.10G132200 No alias myb domain protein 79 0.02 Orthogroups_2024-Update
Glyma.11G009400 No alias myb domain protein 107 0.04 Orthogroups_2024-Update
Glyma.11G021600 No alias myb domain protein 103 0.02 Orthogroups_2024-Update
Glyma.11G045400 No alias myb domain protein 84 0.03 Orthogroups_2024-Update
Glyma.12G057900 No alias myb domain protein 83 0.02 Orthogroups_2024-Update
Glyma.12G106400 No alias MYB-like 102 0.02 Orthogroups_2024-Update
Glyma.15G041100 No alias myb domain protein 48 0.03 Orthogroups_2024-Update
Glyma.16G007200 No alias myb domain protein 4 0.03 Orthogroups_2024-Update
Glyma.16G073000 No alias myb domain protein 21 0.03 Orthogroups_2024-Update
Glyma.19G219000 No alias myb domain protein 112 0.03 Orthogroups_2024-Update
HORVU4Hr1G023510.2 No alias MYB class-R2R3 subgroup-1 transcription factor 0.03 Orthogroups_2024-Update
LOC_Os01g07450 No alias MYB family transcription factor, putative, expressed 0.03 Orthogroups_2024-Update
LOC_Os01g50720 No alias MYB family transcription factor, putative, expressed 0.03 Orthogroups_2024-Update
LOC_Os04g38740 No alias MYB family transcription factor, putative, expressed 0.03 Orthogroups_2024-Update
LOC_Os05g41166 No alias MYB family transcription factor, putative, expressed 0.03 Orthogroups_2024-Update
LOC_Os05g46610 No alias myb-like DNA-binding domain containing protein,... 0.03 Orthogroups_2024-Update
LOC_Os05g48010 No alias MYB family transcription factor, putative, expressed 0.03 Orthogroups_2024-Update
LOC_Os08g15020 No alias MYB family transcription factor, putative, expressed 0.03 Orthogroups_2024-Update
MA_101790g0010 No alias (at4g38620 : 241.0) Encodes a R2R3 MYB protein which is... 0.04 Orthogroups_2024-Update
MA_121533g0010 No alias (at5g57620 : 234.0) Encodes a putative transcription... 0.03 Orthogroups_2024-Update
MA_190973g0010 No alias (p20026|myb1_horvu : 239.0) Myb-related protein Hv1 -... 0.04 Orthogroups_2024-Update
MA_23242g0010 No alias (at1g22640 : 201.0) MYB-type transcription factor (MYB3)... 0.03 Orthogroups_2024-Update
MA_246142g0010 No alias (at4g38620 : 256.0) Encodes a R2R3 MYB protein which is... 0.03 Orthogroups_2024-Update
MA_55123g0010 No alias (p20026|myb1_horvu : 251.0) Myb-related protein Hv1 -... 0.03 Orthogroups_2024-Update
MA_94467g0010 No alias (at3g13540 : 228.0) Encodes a member of the MYB family... 0.03 Orthogroups_2024-Update
PSME_00014640-RA No alias (at3g27810 : 179.0) Encodes a member of the R2R3-MYB... 0.04 Orthogroups_2024-Update
PSME_00035013-RA No alias (at4g38620 : 257.0) Encodes a R2R3 MYB protein which is... 0.04 Orthogroups_2024-Update
PSME_00036696-RA No alias (at5g16770 : 208.0) Member of the R2R3 factor gene... 0.04 Orthogroups_2024-Update
PSME_00049306-RA No alias (at5g15310 : 258.0) Member of the R2R3 factor gene... 0.04 Orthogroups_2024-Update
PSME_00050866-RA No alias (at1g22640 : 150.0) MYB-type transcription factor (MYB3)... 0.04 Orthogroups_2024-Update
PSME_00051072-RA No alias (at4g34990 : 160.0) Member of the R2R3 factor gene... 0.02 Orthogroups_2024-Update
PSME_00052494-RA No alias (q7xbh4|myb4_orysa : 219.0) Myb-related protein Myb4... 0.03 Orthogroups_2024-Update
Potri.005G112000 No alias myb domain protein 4 0.02 Orthogroups_2024-Update
Potri.006G123400 No alias myb domain protein 36 0.03 Orthogroups_2024-Update
Potri.010G123000 No alias myb domain protein 62 0.02 Orthogroups_2024-Update
Potri.014G111200 No alias myb domain protein 55 0.03 Orthogroups_2024-Update
Potri.015G067700 No alias Duplicated homeodomain-like superfamily protein 0.02 Orthogroups_2024-Update
Pp1s61_196V6 No alias myb transcription factor myb92 0.02 Orthogroups_2024-Update
Seita.2G351400.1 No alias MYB class-R2R3 subgroup-11 transcription factor 0.02 Orthogroups_2024-Update
Seita.7G161400.1 No alias MYB class-R2R3 transcription factor 0.03 Orthogroups_2024-Update
Seita.7G179600.1 No alias regulatory protein *(LAF1) of phytochrome signalling... 0.03 Orthogroups_2024-Update
Seita.7G284800.1 No alias MYB class-R2R3 subgroup-4 transcription factor & MYB... 0.03 Orthogroups_2024-Update
Sobic.001G183100.1 No alias MYB class-R2R3 subgroup-18 transcription factor 0.03 Orthogroups_2024-Update
Sobic.003G087600.1 No alias MYB class-R2R3 subgroup-19/20 transcription factor 0.02 Orthogroups_2024-Update
Sobic.003G142300.1 No alias MYB class-R2R3 subgroup-19/20 transcription factor 0.03 Orthogroups_2024-Update
Sobic.004G248700.1 No alias MYB class-R2R3 transcription factor 0.04 Orthogroups_2024-Update
Sobic.004G303400.1 No alias accessory protein (LMI2) of floral meristem identity control 0.03 Orthogroups_2024-Update
Sobic.005G020200.2 No alias MYB class-R2R3 subgroup-1 transcription factor 0.03 Orthogroups_2024-Update
Sobic.007G224800.1 No alias MYB class-R2R3 subgroup-10/24 transcription factor 0.02 Orthogroups_2024-Update
Sobic.008G112200.1 No alias MYB class-R2R3 transcription factor 0.02 Orthogroups_2024-Update
Sobic.008G131400.1 No alias MYB class-R2R3 subgroup-19/20 transcription factor 0.03 Orthogroups_2024-Update
Sobic.009G148100.1 No alias MYB class-R2R3 subgroup-4 transcription factor 0.03 Orthogroups_2024-Update
Solyc02g082040 No alias R2R3MYB transcription factor 56 0.03 Orthogroups_2024-Update
Solyc07g008010 No alias R2R3MYB transcription factor 82 0.03 Orthogroups_2024-Update
Solyc10g008700 No alias R2R3MYB transcription factor 49 0.03 Orthogroups_2024-Update
Solyc11g073120 No alias R2R3MYB transcription factor 58 0.03 Orthogroups_2024-Update
Sopen07g026840 No alias Myb-like DNA-binding domain 0.03 Orthogroups_2024-Update
Sopen08g019610 No alias Myb-like DNA-binding domain 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source
MF GO:0004618 phosphoglycerate kinase activity IEP Predicted GO
MF GO:0005088 Ras guanyl-nucleotide exchange factor activity IEP Predicted GO
MF GO:0005089 Rho guanyl-nucleotide exchange factor activity IEP Predicted GO
MF GO:0010181 FMN binding IEP Predicted GO
MF GO:0015267 channel activity IEP Predicted GO
MF GO:0016491 oxidoreductase activity IEP Predicted GO
MF GO:0016774 phosphotransferase activity, carboxyl group as acceptor IEP Predicted GO
MF GO:0017048 Rho GTPase binding IEP Predicted GO
MF GO:0022803 passive transmembrane transporter activity IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
MF GO:0048037 cofactor binding IEP Predicted GO
MF GO:0050662 coenzyme binding IEP Predicted GO
BP GO:0055114 oxidation-reduction process IEP Predicted GO
MF GO:0098772 molecular function regulator IEP Predicted GO
InterPro domains Description Start Stop
IPR001005 SANT/Myb 19 66
IPR001005 SANT/Myb 72 116
No external refs found!