- Home
- Species
- Pseudotsuga menziesii
- Sequence
- PSME_00004757-RA
PSME_00004757-RA
Description : (at4g02070 : 179.0) encodes a DNA mismatch repair homolog of human MutS gene, MSH6. There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2*MSH6 bound the (+T) substrate strongly, (T/G) well, and (+AAG) no better than it did a (T/A) homoduplex.; MUTS homolog 6 (MSH6); FUNCTIONS IN: damaged DNA binding; INVOLVED IN: mismatch repair; LOCATED IN: chloroplast; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein Msh6 (InterPro:IPR017261), DNA mismatch repair protein MutS, clamp (InterPro:IPR007861), DNA mismatch repair protein MutS, connector (InterPro:IPR007860), DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695), DNA mismatch repair protein MutS, N-terminal (InterPro:IPR016151), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-homologue MSH6 (InterPro:IPR015536), Tudor domain (InterPro:IPR002999); BEST Arabidopsis thaliana protein match is: homolog of DNA mismatch repair protein MSH3 (TAIR:AT4G25540.1). & (reliability: 358.0) & (original description: no original description)
Expression Profile
Attention: This gene has low abundance.
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Co-expression Networks
Type | Description | Actions |
Neighborhood | Pseudotsuga release: PSME_00004757-RA | |
Cluster | HCCA clusters: Cluster_97 | |
Functional Annotation
Type | GO Term | Name | Evidence | Source |
MF | GO:0000166 | nucleotide binding | None | Extended |
MF | GO:0003674 | molecular_function | None | Extended |
MF | GO:0003676 | nucleic acid binding | None | Extended |
MF | GO:0003677 | DNA binding | None | Extended |
MF | GO:0003690 | double-stranded DNA binding | None | Extended |
MF | GO:0005488 | binding | None | Extended |
MF | GO:0005524 | ATP binding | IEA | InterProScan predictions |
BP | GO:0006139 | nucleobase-containing compound metabolic process | None | Extended |
BP | GO:0006259 | DNA metabolic process | None | Extended |
BP | GO:0006281 | DNA repair | None | Extended |
BP | GO:0006298 | mismatch repair | IEA | InterProScan predictions |
BP | GO:0006725 | cellular aromatic compound metabolic process | None | Extended |
BP | GO:0006807 | nitrogen compound metabolic process | None | Extended |
BP | GO:0006950 | response to stress | None | Extended |
BP | GO:0006974 | cellular response to DNA damage stimulus | None | Extended |
MF | GO:0008144 | drug binding | None | Extended |
BP | GO:0008150 | biological_process | None | Extended |
BP | GO:0008152 | metabolic process | None | Extended |
BP | GO:0009987 | cellular process | None | Extended |
MF | GO:0017076 | purine nucleotide binding | None | Extended |
MF | GO:0030554 | adenyl nucleotide binding | None | Extended |
MF | GO:0030983 | mismatched DNA binding | IEA | InterProScan predictions |
MF | GO:0032553 | ribonucleotide binding | None | Extended |
MF | GO:0032555 | purine ribonucleotide binding | None | Extended |
MF | GO:0032559 | adenyl ribonucleotide binding | None | Extended |
BP | GO:0033554 | cellular response to stress | None | Extended |
BP | GO:0034641 | cellular nitrogen compound metabolic process | None | Extended |
MF | GO:0035639 | purine ribonucleoside triphosphate binding | None | Extended |
MF | GO:0036094 | small molecule binding | None | Extended |
MF | GO:0043167 | ion binding | None | Extended |
MF | GO:0043168 | anion binding | None | Extended |
BP | GO:0043170 | macromolecule metabolic process | None | Extended |
BP | GO:0044237 | cellular metabolic process | None | Extended |
BP | GO:0044238 | primary metabolic process | None | Extended |
BP | GO:0044260 | cellular macromolecule metabolic process | None | Extended |
BP | GO:0046483 | heterocycle metabolic process | None | Extended |
BP | GO:0050896 | response to stimulus | None | Extended |
BP | GO:0051716 | cellular response to stimulus | None | Extended |
BP | GO:0071704 | organic substance metabolic process | None | Extended |
BP | GO:0090304 | nucleic acid metabolic process | None | Extended |
MF | GO:0097159 | organic cyclic compound binding | None | Extended |
MF | GO:0097367 | carbohydrate derivative binding | None | Extended |
MF | GO:1901265 | nucleoside phosphate binding | None | Extended |
BP | GO:1901360 | organic cyclic compound metabolic process | None | Extended |
MF | GO:1901363 | heterocyclic compound binding | None | Extended |
Type | GO Term | Name | Evidence | Source |
MF | GO:0000295 | adenine nucleotide transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0001882 | nucleoside binding | IEP | Predicted GO |
MF | GO:0001883 | purine nucleoside binding | IEP | Predicted GO |
MF | GO:0003682 | chromatin binding | IEP | Predicted GO |
MF | GO:0003723 | RNA binding | IEP | Predicted GO |
MF | GO:0003924 | GTPase activity | IEP | Predicted GO |
MF | GO:0004386 | helicase activity | IEP | Predicted GO |
MF | GO:0004497 | monooxygenase activity | IEP | Predicted GO |
MF | GO:0005346 | purine ribonucleotide transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0005347 | ATP transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0005471 | ATP:ADP antiporter activity | IEP | Predicted GO |
MF | GO:0005525 | GTP binding | IEP | Predicted GO |
BP | GO:0006862 | nucleotide transport | IEP | Predicted GO |
MF | GO:0008270 | zinc ion binding | IEP | Predicted GO |
MF | GO:0008514 | organic anion transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0010277 | chlorophyllide a oxygenase [overall] activity | IEP | Predicted GO |
MF | GO:0015215 | nucleotide transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0015216 | purine nucleotide transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0015217 | ADP transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0015301 | anion:anion antiporter activity | IEP | Predicted GO |
MF | GO:0015605 | organophosphate ester transmembrane transporter activity | IEP | Predicted GO |
BP | GO:0015748 | organophosphate ester transport | IEP | Predicted GO |
BP | GO:0015931 | nucleobase-containing compound transport | IEP | Predicted GO |
MF | GO:0015932 | nucleobase-containing compound transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0016462 | pyrophosphatase activity | IEP | Predicted GO |
MF | GO:0016703 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) | IEP | Predicted GO |
MF | GO:0016817 | hydrolase activity, acting on acid anhydrides | IEP | Predicted GO |
MF | GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | IEP | Predicted GO |
MF | GO:0017111 | nucleoside-triphosphatase activity | IEP | Predicted GO |
MF | GO:0019001 | guanyl nucleotide binding | IEP | Predicted GO |
MF | GO:0032549 | ribonucleoside binding | IEP | Predicted GO |
MF | GO:0032550 | purine ribonucleoside binding | IEP | Predicted GO |
MF | GO:0032561 | guanyl ribonucleotide binding | IEP | Predicted GO |
MF | GO:0051536 | iron-sulfur cluster binding | IEP | Predicted GO |
MF | GO:0051537 | 2 iron, 2 sulfur cluster binding | IEP | Predicted GO |
MF | GO:0051540 | metal cluster binding | IEP | Predicted GO |
BP | GO:0071702 | organic substance transport | IEP | Predicted GO |
BP | GO:0071705 | nitrogen compound transport | IEP | Predicted GO |
MF | GO:0099516 | ion antiporter activity | IEP | Predicted GO |
MF | GO:1901505 | carbohydrate derivative transmembrane transporter activity | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
IPR007861 | DNA_mismatch_repair_MutS_clamp | 96 | 167 |