Description : (at1g15750 : 1506.0) Encodes a protein with several WD40 repeats at the C-terminus and predicted protein-protein interaction domains at the N-terminus. Together with the TOPLESS-RELATED PROTEINS (TPRs), it is thought to be involved in transcriptional repression of root-promoting genes in the top help of the embryo during the transition stage of embryogenesis. The ability of IAA12 to repress transcription is diminished in a tpl-1 mutant background.; TOPLESS (TPL); FUNCTIONS IN: protein binding, transcription repressor activity, protein homodimerization activity; INVOLVED IN: xylem and phloem pattern formation, response to auxin stimulus, primary shoot apical meristem specification, jasmonic acid mediated signaling pathway; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), CTLH, C-terminal LisH motif (InterPro:IPR006595), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), LisH dimerisation motif (InterPro:IPR006594), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: TOPLESS-related 1 (TAIR:AT1G80490.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 3012.0) & (original description: no original description)
Gene families : OG_42_0000373 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000373_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00004967-RA | |
Cluster | HCCA clusters: Cluster_140 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
Brara.B03566.1 | No alias | auxin signalling transcriptional co-repressor *(TPL/TPR)... | 0.03 | Orthogroups_2024-Update | |
Glyma.07G028000 | No alias | Transducin family protein / WD-40 repeat family protein | 0.03 | Orthogroups_2024-Update | |
Glyma.19G230500 | No alias | TOPLESS-related 3 | 0.02 | Orthogroups_2024-Update | |
Seita.6G051500.1 | No alias | auxin signalling transcriptional co-repressor *(TPL/TPR)... | 0.02 | Orthogroups_2024-Update | |
Solyc01g100050 | No alias | TOPLESS 3 | 0.02 | Orthogroups_2024-Update | |
Solyc03g117360 | No alias | TOPLESS1 | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005515 | protein binding | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004222 | metalloendopeptidase activity | IEP | Predicted GO |
MF | GO:0004402 | histone acetyltransferase activity | IEP | Predicted GO |
MF | GO:0004559 | alpha-mannosidase activity | IEP | Predicted GO |
MF | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity | IEP | Predicted GO |
MF | GO:0004674 | protein serine/threonine kinase activity | IEP | Predicted GO |
MF | GO:0005516 | calmodulin binding | IEP | Predicted GO |
CC | GO:0005667 | transcription factor complex | IEP | Predicted GO |
CC | GO:0005672 | transcription factor TFIIA complex | IEP | Predicted GO |
BP | GO:0006352 | DNA-templated transcription, initiation | IEP | Predicted GO |
BP | GO:0006367 | transcription initiation from RNA polymerase II promoter | IEP | Predicted GO |
BP | GO:0006473 | protein acetylation | IEP | Predicted GO |
BP | GO:0006475 | internal protein amino acid acetylation | IEP | Predicted GO |
BP | GO:0007155 | cell adhesion | IEP | Predicted GO |
BP | GO:0007186 | G protein-coupled receptor signaling pathway | IEP | Predicted GO |
MF | GO:0008080 | N-acetyltransferase activity | IEP | Predicted GO |
MF | GO:0008237 | metallopeptidase activity | IEP | Predicted GO |
MF | GO:0009055 | electron transfer activity | IEP | Predicted GO |
MF | GO:0015035 | protein disulfide oxidoreductase activity | IEP | Predicted GO |
MF | GO:0015036 | disulfide oxidoreductase activity | IEP | Predicted GO |
MF | GO:0015923 | mannosidase activity | IEP | Predicted GO |
MF | GO:0015924 | mannosyl-oligosaccharide mannosidase activity | IEP | Predicted GO |
MF | GO:0016407 | acetyltransferase activity | IEP | Predicted GO |
MF | GO:0016410 | N-acyltransferase activity | IEP | Predicted GO |
BP | GO:0016569 | covalent chromatin modification | IEP | Predicted GO |
BP | GO:0016570 | histone modification | IEP | Predicted GO |
BP | GO:0016573 | histone acetylation | IEP | Predicted GO |
MF | GO:0016667 | oxidoreductase activity, acting on a sulfur group of donors | IEP | Predicted GO |
BP | GO:0018205 | peptidyl-lysine modification | IEP | Predicted GO |
BP | GO:0018393 | internal peptidyl-lysine acetylation | IEP | Predicted GO |
BP | GO:0018394 | peptidyl-lysine acetylation | IEP | Predicted GO |
BP | GO:0022610 | biological adhesion | IEP | Predicted GO |
MF | GO:0031683 | G-protein beta/gamma-subunit complex binding | IEP | Predicted GO |
MF | GO:0034212 | peptide N-acetyltransferase activity | IEP | Predicted GO |
BP | GO:0043543 | protein acylation | IEP | Predicted GO |
CC | GO:0044451 | nucleoplasm part | IEP | Predicted GO |
CC | GO:0044798 | nuclear transcription factor complex | IEP | Predicted GO |
MF | GO:0044877 | protein-containing complex binding | IEP | Predicted GO |
BP | GO:0050789 | regulation of biological process | IEP | Predicted GO |
BP | GO:0050794 | regulation of cellular process | IEP | Predicted GO |
MF | GO:0061733 | peptide-lysine-N-acetyltransferase activity | IEP | Predicted GO |
BP | GO:0065007 | biological regulation | IEP | Predicted GO |
CC | GO:0090575 | RNA polymerase II transcription factor complex | IEP | Predicted GO |
No external refs found! |