PSME_00004967-RA


Description : (at1g15750 : 1506.0) Encodes a protein with several WD40 repeats at the C-terminus and predicted protein-protein interaction domains at the N-terminus. Together with the TOPLESS-RELATED PROTEINS (TPRs), it is thought to be involved in transcriptional repression of root-promoting genes in the top help of the embryo during the transition stage of embryogenesis. The ability of IAA12 to repress transcription is diminished in a tpl-1 mutant background.; TOPLESS (TPL); FUNCTIONS IN: protein binding, transcription repressor activity, protein homodimerization activity; INVOLVED IN: xylem and phloem pattern formation, response to auxin stimulus, primary shoot apical meristem specification, jasmonic acid mediated signaling pathway; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), CTLH, C-terminal LisH motif (InterPro:IPR006595), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), LisH dimerisation motif (InterPro:IPR006594), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: TOPLESS-related 1 (TAIR:AT1G80490.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 3012.0) & (original description: no original description)


Gene families : OG_42_0000373 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000373_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00004967-RA
Cluster HCCA clusters: Cluster_140

Target Alias Description ECC score Gene Family Method Actions
Brara.B03566.1 No alias auxin signalling transcriptional co-repressor *(TPL/TPR)... 0.03 Orthogroups_2024-Update
Glyma.07G028000 No alias Transducin family protein / WD-40 repeat family protein 0.03 Orthogroups_2024-Update
Glyma.19G230500 No alias TOPLESS-related 3 0.02 Orthogroups_2024-Update
Seita.6G051500.1 No alias auxin signalling transcriptional co-repressor *(TPL/TPR)... 0.02 Orthogroups_2024-Update
Solyc01g100050 No alias TOPLESS 3 0.02 Orthogroups_2024-Update
Solyc03g117360 No alias TOPLESS1 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0004222 metalloendopeptidase activity IEP Predicted GO
MF GO:0004402 histone acetyltransferase activity IEP Predicted GO
MF GO:0004559 alpha-mannosidase activity IEP Predicted GO
MF GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity IEP Predicted GO
MF GO:0004674 protein serine/threonine kinase activity IEP Predicted GO
MF GO:0005516 calmodulin binding IEP Predicted GO
CC GO:0005667 transcription factor complex IEP Predicted GO
CC GO:0005672 transcription factor TFIIA complex IEP Predicted GO
BP GO:0006352 DNA-templated transcription, initiation IEP Predicted GO
BP GO:0006367 transcription initiation from RNA polymerase II promoter IEP Predicted GO
BP GO:0006473 protein acetylation IEP Predicted GO
BP GO:0006475 internal protein amino acid acetylation IEP Predicted GO
BP GO:0007155 cell adhesion IEP Predicted GO
BP GO:0007186 G protein-coupled receptor signaling pathway IEP Predicted GO
MF GO:0008080 N-acetyltransferase activity IEP Predicted GO
MF GO:0008237 metallopeptidase activity IEP Predicted GO
MF GO:0009055 electron transfer activity IEP Predicted GO
MF GO:0015035 protein disulfide oxidoreductase activity IEP Predicted GO
MF GO:0015036 disulfide oxidoreductase activity IEP Predicted GO
MF GO:0015923 mannosidase activity IEP Predicted GO
MF GO:0015924 mannosyl-oligosaccharide mannosidase activity IEP Predicted GO
MF GO:0016407 acetyltransferase activity IEP Predicted GO
MF GO:0016410 N-acyltransferase activity IEP Predicted GO
BP GO:0016569 covalent chromatin modification IEP Predicted GO
BP GO:0016570 histone modification IEP Predicted GO
BP GO:0016573 histone acetylation IEP Predicted GO
MF GO:0016667 oxidoreductase activity, acting on a sulfur group of donors IEP Predicted GO
BP GO:0018205 peptidyl-lysine modification IEP Predicted GO
BP GO:0018393 internal peptidyl-lysine acetylation IEP Predicted GO
BP GO:0018394 peptidyl-lysine acetylation IEP Predicted GO
BP GO:0022610 biological adhesion IEP Predicted GO
MF GO:0031683 G-protein beta/gamma-subunit complex binding IEP Predicted GO
MF GO:0034212 peptide N-acetyltransferase activity IEP Predicted GO
BP GO:0043543 protein acylation IEP Predicted GO
CC GO:0044451 nucleoplasm part IEP Predicted GO
CC GO:0044798 nuclear transcription factor complex IEP Predicted GO
MF GO:0044877 protein-containing complex binding IEP Predicted GO
BP GO:0050789 regulation of biological process IEP Predicted GO
BP GO:0050794 regulation of cellular process IEP Predicted GO
MF GO:0061733 peptide-lysine-N-acetyltransferase activity IEP Predicted GO
BP GO:0065007 biological regulation IEP Predicted GO
CC GO:0090575 RNA polymerase II transcription factor complex IEP Predicted GO
InterPro domains Description Start Stop
IPR001680 WD40_repeat 974 1007
IPR001680 WD40_repeat 505 539
No external refs found!