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Description : (at1g15750 : 384.0) Encodes a protein with several WD40 repeats at the C-terminus and predicted protein-protein interaction domains at the N-terminus. Together with the TOPLESS-RELATED PROTEINS (TPRs), it is thought to be involved in transcriptional repression of root-promoting genes in the top help of the embryo during the transition stage of embryogenesis. The ability of IAA12 to repress transcription is diminished in a tpl-1 mutant background.; TOPLESS (TPL); FUNCTIONS IN: protein binding, transcription repressor activity, protein homodimerization activity; INVOLVED IN: xylem and phloem pattern formation, response to auxin stimulus, primary shoot apical meristem specification, jasmonic acid mediated signaling pathway; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), CTLH, C-terminal LisH motif (InterPro:IPR006595), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), LisH dimerisation motif (InterPro:IPR006594), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: TOPLESS-related 1 (TAIR:AT1G80490.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 768.0) & (original description: no original description)
Gene families : OG_42_0000373 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000373_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | Pseudotsuga release: PSME_00004968-RA | |
| Cluster | HCCA clusters: Cluster_219 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| 439915 | No alias | TOPLESS-related 1 | 0.03 | Orthogroups_2024-Update | |
| Glyma.13G367300 | No alias | TOPLESS-related 1 | 0.02 | Orthogroups_2024-Update |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No GO annotation available for this sequence |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0003824 | catalytic activity | IEP | Predicted GO |
| MF | GO:0004601 | peroxidase activity | IEP | Predicted GO |
| BP | GO:0006950 | response to stress | IEP | Predicted GO |
| BP | GO:0006979 | response to oxidative stress | IEP | Predicted GO |
| CC | GO:0016020 | membrane | IEP | Predicted GO |
| MF | GO:0016209 | antioxidant activity | IEP | Predicted GO |
| MF | GO:0016684 | oxidoreductase activity, acting on peroxide as acceptor | IEP | Predicted GO |
| MF | GO:0016787 | hydrolase activity | IEP | Predicted GO |
| MF | GO:0016887 | ATPase activity | IEP | Predicted GO |
| MF | GO:0020037 | heme binding | IEP | Predicted GO |
| MF | GO:0046906 | tetrapyrrole binding | IEP | Predicted GO |
| MF | GO:0048037 | cofactor binding | IEP | Predicted GO |
| BP | GO:0050896 | response to stimulus | IEP | Predicted GO |
| MF | GO:0051536 | iron-sulfur cluster binding | IEP | Predicted GO |
| MF | GO:0051540 | metal cluster binding | IEP | Predicted GO |
No InterPro domains available for this sequence
| No external refs found! |