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PSME_00005061-RA


Description : (at3g24495 : 349.0) encodes a DNA mismatch repair homolog of human MutS gene, MSH6. There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2*MSH7 exhibit moderate affinity for a (T/G) substrate and weak binding of (+T), suggesting MSH2*MSH7 may be specialized for lesions/base mispairs not tested or for (T/G) mispairs in special contexts.; MUTS homolog 7 (MSH7); FUNCTIONS IN: damaged DNA binding, mismatched DNA binding, ATP binding; INVOLVED IN: mismatch repair; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein MutS, connector (InterPro:IPR007860), DNA mismatch repair protein MutS, N-terminal (InterPro:IPR016151), DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-homologue MSH6 (InterPro:IPR015536), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695); BEST Arabidopsis thaliana protein match is: MUTS homolog 6 (TAIR:AT4G02070.2); Has 17871 Blast hits to 13835 proteins in 2667 species: Archae - 197; Bacteria - 11731; Metazoa - 1028; Fungi - 1274; Plants - 566; Viruses - 3; Other Eukaryotes - 3072 (source: NCBI BLink). & (q9xgc9|msh2_maize : 155.0) DNA mismatch repair protein MSH2 (MUS1) - Zea mays (Maize) & (reliability: 698.0) & (original description: no original description)


Gene families : OG_42_0001047 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001047_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00005061-RA
Cluster HCCA clusters: Cluster_234

Target Alias Description ECC score Gene Family Method Actions
Glyma.03G219033 No alias MUTS homolog 6 0.02 Orthogroups_2024-Update
Kfl00153_0160 kfl00153_0160_v1.1 (at4g02070 : 834.0) encodes a DNA mismatch repair... 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0005524 ATP binding IEA InterProScan predictions
BP GO:0006298 mismatch repair IEA InterProScan predictions
BP GO:0016226 iron-sulfur cluster assembly IEA InterProScan predictions
MF GO:0030983 mismatched DNA binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
BP GO:0006801 superoxide metabolic process IEP Predicted GO
MF GO:0008897 holo-[acyl-carrier-protein] synthase activity IEP Predicted GO
BP GO:0015985 energy coupled proton transport, down electrochemical gradient IEP Predicted GO
BP GO:0015986 ATP synthesis coupled proton transport IEP Predicted GO
MF GO:0016780 phosphotransferase activity, for other substituted phosphate groups IEP Predicted GO
MF GO:0016853 isomerase activity IEP Predicted GO
BP GO:0030163 protein catabolic process IEP Predicted GO
CC GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain IEP Predicted GO
CC GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o) IEP Predicted GO
BP GO:0072593 reactive oxygen species metabolic process IEP Predicted GO
InterPro domains Description Start Stop
IPR000825 SUF_FeS_clus_asmbl_SufBD 415 457
IPR000432 DNA_mismatch_repair_MutS_C 197 411
No external refs found!