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  5. PSME_00005452-RA

PSME_00005452-RA


Description : (at3g01120 : 565.0) encodes a cystathionine gamma-synthase, which performs the first committed step in methionine biosynthesis. A conserved motif of 13 amino acids in the first exon is required for posttranscriptional autoregulation. This enzyme shares the same substrate as threonine synthase (TS) and its absence transcriptionally affects 8 genes in the genome.; METHIONINE OVERACCUMULATION 1 (MTO1); FUNCTIONS IN: cystathionine gamma-synthase activity; INVOLVED IN: methionine biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (InterPro:IPR000277), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422); BEST Arabidopsis thaliana protein match is: Pyridoxal phosphate (PLP)-dependent transferases superfamily protein (TAIR:AT1G33320.1); Has 21364 Blast hits to 20702 proteins in 2452 species: Archae - 220; Bacteria - 11705; Metazoa - 241; Fungi - 842; Plants - 284; Viruses - 13; Other Eukaryotes - 8059 (source: NCBI BLink). & (reliability: 1130.0) & (original description: no original description)


Gene families : OG_42_0001443 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001443_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00005452-RA
Cluster HCCA clusters: Cluster_235

Target Alias Description ECC score Gene Family Method Actions
143363 No alias Pyridoxal phosphate (PLP)-dependent transferases... 0.03 Orthogroups_2024-Update
Cre03.g144627 No alias Pyridoxal phosphate (PLP)-dependent transferases... 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0030170 pyridoxal phosphate binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEP Predicted GO
MF GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity IEP Predicted GO
MF GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity IEP Predicted GO
BP GO:0006082 organic acid metabolic process IEP Predicted GO
BP GO:0006099 tricarboxylic acid cycle IEP Predicted GO
BP GO:0006101 citrate metabolic process IEP Predicted GO
BP GO:0006364 rRNA processing IEP Predicted GO
BP GO:0009072 aromatic amino acid family metabolic process IEP Predicted GO
BP GO:0009073 aromatic amino acid family biosynthetic process IEP Predicted GO
BP GO:0016072 rRNA metabolic process IEP Predicted GO
MF GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups IEP Predicted GO
MF GO:0016872 intramolecular lyase activity IEP Predicted GO
BP GO:0016999 antibiotic metabolic process IEP Predicted GO
BP GO:0019752 carboxylic acid metabolic process IEP Predicted GO
BP GO:0034470 ncRNA processing IEP Predicted GO
BP GO:0043436 oxoacid metabolic process IEP Predicted GO
BP GO:0044281 small molecule metabolic process IEP Predicted GO
MF GO:0051536 iron-sulfur cluster binding IEP Predicted GO
MF GO:0051540 metal cluster binding IEP Predicted GO
BP GO:0072350 tricarboxylic acid metabolic process IEP Predicted GO
InterPro domains Description Start Stop
IPR000277 Cys/Met-Metab_PyrdxlP-dep_enz 180 498
No external refs found!