PSME_00005940-RA

Description : (at5g15410 : 820.0) 'defense, no death' gene (DND1) encodes a mutated cyclic nucleotide-gated cation channel; Same as CNGC2 (article ID 229): Cyclic nucleotide gated channel, activated by cAMP, conducts K+ and other monovalent cations but excludes Na+, does not contain the GYG amino acid sequence found in other channels with this conductivity profile. Conducts Ca2+ into cells which is linked to the generation of NO and the NO signaling pathway involved in the innate immune response to pathogens.; DEFENSE NO DEATH 1 (DND1); CONTAINS InterPro DOMAIN/s: Cyclic nucleotide-binding (InterPro:IPR000595), Cyclic nucleotide-binding-like (InterPro:IPR018490), RmlC-like jelly roll fold (InterPro:IPR014710); BEST Arabidopsis thaliana protein match is: cyclic nucleotide-gated cation channel 4 (TAIR:AT5G54250.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 1640.0) & (original description: no original description)

Gene families : OG_42_0000108 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000108_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pseudotsuga release: PSME_00005940-RA
Cluster	HCCA clusters: Cluster_64

Target	Alias	Description	ECC score	Gene Family Method
A4A49_19266	No alias	putative cyclic nucleotide-gated ion channel 8	0.02	Orthogroups_2024-Update
A4A49_26569	No alias	putative cyclic nucleotide-gated ion channel 16	0.02	Orthogroups_2024-Update
At3g17690	No alias	Putative cyclic nucleotide-gated ion channel 19...	0.02	Orthogroups_2024-Update
Bradi1g46260	No alias	cyclic nucleotide-binding transporter 1	0.01	Orthogroups_2024-Update
Bradi2g20660	No alias	cyclic nucleotide-gated cation channel 4	0.02	Orthogroups_2024-Update
Bradi3g49290	No alias	cyclic nucleotide-gated channel 15	0.02	Orthogroups_2024-Update
Brara.A02981.1	No alias	cyclic nucleotide-gated cation channel *(CNGC)	0.03	Orthogroups_2024-Update
Brara.C02872.1	No alias	cyclic nucleotide-gated cation channel *(CNGC)	0.03	Orthogroups_2024-Update
LOC_Os04g55080	No alias	cyclic nucleotide-gated ion channel, putative, expressed	0.02	Orthogroups_2024-Update
MA_10437228g0010	No alias	(at3g17690 : 140.0) member of Cyclic nucleotide gated...	0.03	Orthogroups_2024-Update
MA_212367g0010	No alias	(at3g17700 : 183.0) cyclic nucleotide-binding...	0.05	Orthogroups_2024-Update
Potri.002G170000	No alias	cyclic nucleotide gated channel 10	0.02	Orthogroups_2024-Update
Potri.014G097900	No alias	cyclic nucleotide gated channel 1	0.03	Orthogroups_2024-Update
Sopen12g004880	No alias	Ion transport protein	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005215	transporter activity	None	Extended
MF	GO:0005216	ion channel activity	IEA	InterProScan predictions
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
BP	GO:0006811	ion transport	IEA	InterProScan predictions
BP	GO:0008150	biological_process	None	Extended
MF	GO:0015075	ion transmembrane transporter activity	None	Extended
MF	GO:0015267	channel activity	None	Extended
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	None	Extended
CC	GO:0016020	membrane	IEA	InterProScan predictions
MF	GO:0022803	passive transmembrane transporter activity	None	Extended
MF	GO:0022838	substrate-specific channel activity	None	Extended
MF	GO:0022857	transmembrane transporter activity	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0055085	transmembrane transport	IEA	InterProScan predictions

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Type	GO Term	Name	Evidence	Source
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	Predicted GO
MF	GO:0003922	GMP synthase (glutamine-hydrolyzing) activity	IEP	Predicted GO
MF	GO:0004602	glutathione peroxidase activity	IEP	Predicted GO
MF	GO:0004637	phosphoribosylamine-glycine ligase activity	IEP	Predicted GO
MF	GO:0004655	porphobilinogen synthase activity	IEP	Predicted GO
MF	GO:0004672	protein kinase activity	IEP	Predicted GO
MF	GO:0004749	ribose phosphate diphosphokinase activity	IEP	Predicted GO
MF	GO:0004857	enzyme inhibitor activity	IEP	Predicted GO
MF	GO:0004866	endopeptidase inhibitor activity	IEP	Predicted GO
MF	GO:0004869	cysteine-type endopeptidase inhibitor activity	IEP	Predicted GO
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006144	purine nucleobase metabolic process	IEP	Predicted GO
BP	GO:0006163	purine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0006164	purine nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0006177	GMP biosynthetic process	IEP	Predicted GO
BP	GO:0006260	DNA replication	IEP	Predicted GO
BP	GO:0006468	protein phosphorylation	IEP	Predicted GO
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Predicted GO
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Predicted GO
BP	GO:0006793	phosphorus metabolic process	IEP	Predicted GO
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006807	nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0006979	response to oxidative stress	IEP	Predicted GO
MF	GO:0008138	protein tyrosine/serine/threonine phosphatase activity	IEP	Predicted GO
BP	GO:0008152	metabolic process	IEP	Predicted GO
BP	GO:0009058	biosynthetic process	IEP	Predicted GO
BP	GO:0009112	nucleobase metabolic process	IEP	Predicted GO
BP	GO:0009113	purine nucleobase biosynthetic process	IEP	Predicted GO
BP	GO:0009116	nucleoside metabolic process	IEP	Predicted GO
BP	GO:0009117	nucleotide metabolic process	IEP	Predicted GO
BP	GO:0009119	ribonucleoside metabolic process	IEP	Predicted GO
BP	GO:0009123	nucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009124	nucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009126	purine nucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009127	purine nucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009150	purine ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009152	purine ribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009156	ribonucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009161	ribonucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009163	nucleoside biosynthetic process	IEP	Predicted GO
BP	GO:0009165	nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009167	purine ribonucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009259	ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009260	ribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009987	cellular process	IEP	Predicted GO
BP	GO:0016310	phosphorylation	IEP	Predicted GO
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	Predicted GO
MF	GO:0016778	diphosphotransferase activity	IEP	Predicted GO
MF	GO:0016874	ligase activity	IEP	Predicted GO
MF	GO:0016879	ligase activity, forming carbon-nitrogen bonds	IEP	Predicted GO
MF	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	IEP	Predicted GO
BP	GO:0018130	heterocycle biosynthetic process	IEP	Predicted GO
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Predicted GO
BP	GO:0019637	organophosphate metabolic process	IEP	Predicted GO
BP	GO:0019693	ribose phosphate metabolic process	IEP	Predicted GO
MF	GO:0030234	enzyme regulator activity	IEP	Predicted GO
BP	GO:0030258	lipid modification	IEP	Predicted GO
MF	GO:0030414	peptidase inhibitor activity	IEP	Predicted GO
CC	GO:0030684	preribosome	IEP	Predicted GO
CC	GO:0032040	small-subunit processome	IEP	Predicted GO
BP	GO:0033013	tetrapyrrole metabolic process	IEP	Predicted GO
BP	GO:0033014	tetrapyrrole biosynthetic process	IEP	Predicted GO
MF	GO:0034061	DNA polymerase activity	IEP	Predicted GO
BP	GO:0034404	nucleobase-containing small molecule biosynthetic process	IEP	Predicted GO
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0042278	purine nucleoside metabolic process	IEP	Predicted GO
BP	GO:0042440	pigment metabolic process	IEP	Predicted GO
BP	GO:0042451	purine nucleoside biosynthetic process	IEP	Predicted GO
BP	GO:0042455	ribonucleoside biosynthetic process	IEP	Predicted GO
MF	GO:0043531	ADP binding	IEP	Predicted GO
BP	GO:0044237	cellular metabolic process	IEP	Predicted GO
BP	GO:0044238	primary metabolic process	IEP	Predicted GO
BP	GO:0044249	cellular biosynthetic process	IEP	Predicted GO
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Predicted GO
BP	GO:0044281	small molecule metabolic process	IEP	Predicted GO
BP	GO:0046037	GMP metabolic process	IEP	Predicted GO
BP	GO:0046112	nucleobase biosynthetic process	IEP	Predicted GO
BP	GO:0046128	purine ribonucleoside metabolic process	IEP	Predicted GO
BP	GO:0046129	purine ribonucleoside biosynthetic process	IEP	Predicted GO
BP	GO:0046148	pigment biosynthetic process	IEP	Predicted GO
BP	GO:0046390	ribose phosphate biosynthetic process	IEP	Predicted GO
BP	GO:0046483	heterocycle metabolic process	IEP	Predicted GO
BP	GO:0046834	lipid phosphorylation	IEP	Predicted GO
BP	GO:0046854	phosphatidylinositol phosphorylation	IEP	Predicted GO
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Predicted GO
MF	GO:0061134	peptidase regulator activity	IEP	Predicted GO
MF	GO:0061135	endopeptidase regulator activity	IEP	Predicted GO
BP	GO:0071704	organic substance metabolic process	IEP	Predicted GO
BP	GO:0072521	purine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072522	purine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0090407	organophosphate biosynthetic process	IEP	Predicted GO
BP	GO:1901068	guanosine-containing compound metabolic process	IEP	Predicted GO
BP	GO:1901070	guanosine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:1901137	carbohydrate derivative biosynthetic process	IEP	Predicted GO
BP	GO:1901293	nucleoside phosphate biosynthetic process	IEP	Predicted GO
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Predicted GO
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Predicted GO
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Predicted GO
BP	GO:1901576	organic substance biosynthetic process	IEP	Predicted GO
BP	GO:1901657	glycosyl compound metabolic process	IEP	Predicted GO
BP	GO:1901659	glycosyl compound biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR005821	Ion_trans_dom	123	443
IPR000595	cNMP-bd_dom	546	633

External Links

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PSME_00005940-RA

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation