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  5. PSME_00006384-RA

PSME_00006384-RA


Description : (o24146|4cl2_tobac : 768.0) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2) (4-coumaroyl-CoA synthase 2) - Nicotiana tabacum (Common tobacco) & (at1g51680 : 723.0) encodes an isoform of 4-coumarate:CoA ligase (4CL), which is involved in the last step of the general phenylpropanoid pathway. In addition to 4-coumarate, it also converts ferulate. The catalytic efficiency was in the following (descending) order: p-coumaric acid, ferulic acid, caffeic acid and 5-OH-ferulic acid. At4CL1 was unable to use sinapic acid as substrate.; 4-coumarate:CoA ligase 1 (4CL1); CONTAINS InterPro DOMAIN/s: AMP-binding, conserved site (InterPro:IPR020845), AMP-dependent synthetase/ligase (InterPro:IPR000873); BEST Arabidopsis thaliana protein match is: 4-coumarate:CoA ligase 2 (TAIR:AT3G21240.1); Has 83069 Blast hits to 75791 proteins in 3772 species: Archae - 1181; Bacteria - 53827; Metazoa - 3457; Fungi - 4480; Plants - 2791; Viruses - 1; Other Eukaryotes - 17332 (source: NCBI BLink). & (reliability: 1446.0) & (original description: no original description)


Gene families : OG_42_0000133 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000133_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00006384-RA
Cluster HCCA clusters: Cluster_215

Target Alias Description ECC score Gene Family Method Actions
Glyma.11G091600 No alias 4-coumarate:CoA ligase 3 0.03 Orthogroups_2024-Update
LOC_Os03g04000 No alias AMP-binding domain containing protein, expressed 0.02 Orthogroups_2024-Update
MA_103893g0010 No alias (at1g20510 : 417.0) OPC-8:0 CoA ligase1 (OPCL1);... 0.04 Orthogroups_2024-Update
MA_10426159g0010 No alias (at1g20510 : 528.0) OPC-8:0 CoA ligase1 (OPCL1);... 0.03 Orthogroups_2024-Update
MA_10432069g0020 No alias (at1g20510 : 391.0) OPC-8:0 CoA ligase1 (OPCL1);... 0.03 Orthogroups_2024-Update
MA_10922g0010 No alias (at1g20510 : 573.0) OPC-8:0 CoA ligase1 (OPCL1);... 0.03 Orthogroups_2024-Update
MA_14460g0010 No alias (at1g20510 : 613.0) OPC-8:0 CoA ligase1 (OPCL1);... 0.07 Orthogroups_2024-Update
PSME_00024856-RA No alias (at1g20510 : 521.0) OPC-8:0 CoA ligase1 (OPCL1);... 0.04 Orthogroups_2024-Update
Potri.010G230200 No alias OPC-8:0 CoA ligase1 0.02 Orthogroups_2024-Update
Seita.1G065800.1 No alias p-coumarate 0.03 Orthogroups_2024-Update
Seita.9G184000.1 No alias Unknown function 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0001871 pattern binding IEP Predicted GO
MF GO:0004672 protein kinase activity IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
BP GO:0006464 cellular protein modification process IEP Predicted GO
BP GO:0006468 protein phosphorylation IEP Predicted GO
BP GO:0006793 phosphorus metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
MF GO:0016301 kinase activity IEP Predicted GO
BP GO:0016310 phosphorylation IEP Predicted GO
MF GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor IEP Predicted GO
MF GO:0016651 oxidoreductase activity, acting on NAD(P)H IEP Predicted GO
MF GO:0016740 transferase activity IEP Predicted GO
MF GO:0016772 transferase activity, transferring phosphorus-containing groups IEP Predicted GO
MF GO:0016773 phosphotransferase activity, alcohol group as acceptor IEP Predicted GO
MF GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors IEP Predicted GO
MF GO:0030246 carbohydrate binding IEP Predicted GO
MF GO:0030247 polysaccharide binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
BP GO:0036211 protein modification process IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
BP GO:0043412 macromolecule modification IEP Predicted GO
BP GO:0044267 cellular protein metabolic process IEP Predicted GO
MF GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor IEP Predicted GO
MF GO:0140096 catalytic activity, acting on a protein IEP Predicted GO
InterPro domains Description Start Stop
IPR000873 AMP-dep_Synth/Lig 42 457
IPR025110 AMP-bd_C 466 542
No external refs found!