PSME_00007221-RA


Description : (at3g50660 : 203.0) Encodes a 22α hydroxylase whose reaction is a rate-limiting step in brassinosteroid biosynthetic pathway. The protein is a member of CYP90B gene family. CLM is an epi-allele with small, compressed rosette, reduced internode length, and reduced fertility, appears in selfed ddm mutant plants possibly due to loss of cytosine methylation. Transcripts accumulate in actively growing tissues, and GUS expression is negatively regulated by brassinosteroids. Localized in the endoplasmic reticulum. The in vitro expressed protein can perform the C-22 hydroxylation of a variety of C27-, C28- and C29-sterols. Cholesterol was the best substrate, followed by campesterol. Sitosterol was a poor substrate.; DWARF 4 (DWF4); CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, conserved site (InterPro:IPR017972), Cytochrome P450, E-class, group I (InterPro:IPR002401); BEST Arabidopsis thaliana protein match is: Cytochrome P450 superfamily protein (TAIR:AT5G05690.1); Has 31120 Blast hits to 31036 proteins in 1650 species: Archae - 61; Bacteria - 5303; Metazoa - 10591; Fungi - 5722; Plants - 7996; Viruses - 3; Other Eukaryotes - 1444 (source: NCBI BLink). & (q94iw5|c90d2_orysa : 189.0) Cytochrome P450 90D2 (EC 1.14.-.-) (C6-oxidase) - Oryza sativa (Rice) & (reliability: 406.0) & (original description: no original description)


Gene families : OG_42_0009267 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0009267_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00007221-RA
Cluster HCCA clusters: Cluster_64


Type GO Term Name Evidence Source
MF GO:0005506 iron ion binding IEA InterProScan predictions
MF GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA InterProScan predictions
MF GO:0020037 heme binding IEA InterProScan predictions
BP GO:0055114 oxidation-reduction process IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0000287 magnesium ion binding IEP Predicted GO
BP GO:0006364 rRNA processing IEP Predicted GO
MF GO:0010333 terpene synthase activity IEP Predicted GO
CC GO:0016020 membrane IEP Predicted GO
BP GO:0016072 rRNA metabolic process IEP Predicted GO
MF GO:0016746 transferase activity, transferring acyl groups IEP Predicted GO
MF GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups IEP Predicted GO
MF GO:0016829 lyase activity IEP Predicted GO
MF GO:0016835 carbon-oxygen lyase activity IEP Predicted GO
MF GO:0016838 carbon-oxygen lyase activity, acting on phosphates IEP Predicted GO
BP GO:0022618 ribonucleoprotein complex assembly IEP Predicted GO
CC GO:0030684 preribosome IEP Predicted GO
MF GO:0031625 ubiquitin protein ligase binding IEP Predicted GO
CC GO:0032040 small-subunit processome IEP Predicted GO
BP GO:0042255 ribosome assembly IEP Predicted GO
BP GO:0042256 mature ribosome assembly IEP Predicted GO
MF GO:0043021 ribonucleoprotein complex binding IEP Predicted GO
MF GO:0043022 ribosome binding IEP Predicted GO
MF GO:0044389 ubiquitin-like protein ligase binding IEP Predicted GO
MF GO:0044877 protein-containing complex binding IEP Predicted GO
BP GO:0070925 organelle assembly IEP Predicted GO
BP GO:0071826 ribonucleoprotein complex subunit organization IEP Predicted GO
InterPro domains Description Start Stop
IPR001128 Cyt_P450 41 167
No external refs found!