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  5. PSME_00007223-RA

PSME_00007223-RA


Description : (at3g50660 : 228.0) Encodes a 22α hydroxylase whose reaction is a rate-limiting step in brassinosteroid biosynthetic pathway. The protein is a member of CYP90B gene family. CLM is an epi-allele with small, compressed rosette, reduced internode length, and reduced fertility, appears in selfed ddm mutant plants possibly due to loss of cytosine methylation. Transcripts accumulate in actively growing tissues, and GUS expression is negatively regulated by brassinosteroids. Localized in the endoplasmic reticulum. The in vitro expressed protein can perform the C-22 hydroxylation of a variety of C27-, C28- and C29-sterols. Cholesterol was the best substrate, followed by campesterol. Sitosterol was a poor substrate.; DWARF 4 (DWF4); CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, conserved site (InterPro:IPR017972), Cytochrome P450, E-class, group I (InterPro:IPR002401); BEST Arabidopsis thaliana protein match is: Cytochrome P450 superfamily protein (TAIR:AT5G05690.1); Has 31120 Blast hits to 31036 proteins in 1650 species: Archae - 61; Bacteria - 5303; Metazoa - 10591; Fungi - 5722; Plants - 7996; Viruses - 3; Other Eukaryotes - 1444 (source: NCBI BLink). & (q94iw5|c90d2_orysa : 196.0) Cytochrome P450 90D2 (EC 1.14.-.-) (C6-oxidase) - Oryza sativa (Rice) & (reliability: 456.0) & (original description: no original description)


Gene families : OG_42_0009267 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0009267_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00007223-RA
Cluster HCCA clusters: Cluster_102


Type GO Term Name Evidence Source
MF GO:0005506 iron ion binding IEA InterProScan predictions
MF GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA InterProScan predictions
MF GO:0020037 heme binding IEA InterProScan predictions
BP GO:0055114 oxidation-reduction process IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0000287 magnesium ion binding IEP Predicted GO
MF GO:0004866 endopeptidase inhibitor activity IEP Predicted GO
MF GO:0004869 cysteine-type endopeptidase inhibitor activity IEP Predicted GO
MF GO:0005319 lipid transporter activity IEP Predicted GO
BP GO:0006629 lipid metabolic process IEP Predicted GO
BP GO:0006631 fatty acid metabolic process IEP Predicted GO
BP GO:0006869 lipid transport IEP Predicted GO
MF GO:0010333 terpene synthase activity IEP Predicted GO
MF GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors IEP Predicted GO
MF GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water IEP Predicted GO
MF GO:0016829 lyase activity IEP Predicted GO
MF GO:0016835 carbon-oxygen lyase activity IEP Predicted GO
MF GO:0016838 carbon-oxygen lyase activity, acting on phosphates IEP Predicted GO
MF GO:0030414 peptidase inhibitor activity IEP Predicted GO
BP GO:0032787 monocarboxylic acid metabolic process IEP Predicted GO
BP GO:0044255 cellular lipid metabolic process IEP Predicted GO
MF GO:0045300 acyl-[acyl-carrier-protein] desaturase activity IEP Predicted GO
BP GO:0061024 membrane organization IEP Predicted GO
MF GO:0061134 peptidase regulator activity IEP Predicted GO
MF GO:0061135 endopeptidase regulator activity IEP Predicted GO
BP GO:0120009 intermembrane lipid transfer IEP Predicted GO
MF GO:0120013 intermembrane lipid transfer activity IEP Predicted GO
InterPro domains Description Start Stop
IPR001128 Cyt_P450 83 391
No external refs found!