- Home
- Species
- Pseudotsuga menziesii
- Sequence
- PSME_00007496-RA
PSME_00007496-RA
Description : (at2g30110 : 251.0) Encodes a ubiquitin-activating enzyme (E1), involved in the first step in conjugating multiple ubiquitins to proteins targeted for degradation. Gene is expressed in most tissues examined. Mutant is able to revert the constitutive defense responses phenotype of snc1, which indicates the gene is involved in defense response. It also indicates that ubiquitination plays a role in plant defense signalling.; ubiquitin-activating enzyme 1 (UBA1); FUNCTIONS IN: ubiquitin-protein ligase activity, ubiquitin activating enzyme activity; INVOLVED IN: response to cadmium ion, response to other organism, protein ubiquitination, ubiquitin-dependent protein catabolic process; LOCATED IN: plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ubiquitin-activating enzyme, E1, active site (InterPro:IPR018074), Ubiquitin-activating enzyme, E1 (InterPro:IPR018075), Ubiquitin-activating enzyme e1, C-terminal (InterPro:IPR018965), Ubiquitin-activating enzyme repeat (InterPro:IPR000127), Ubiquitin-activating enzyme (InterPro:IPR019572), UBA/THIF-type NAD/FAD binding fold (InterPro:IPR000594), Molybdenum cofactor biosynthesis, MoeB (InterPro:IPR009036), NAD(P)-binding domain (InterPro:IPR016040), Ubiquitin-activating enzyme, E1-like (InterPro:IPR000011); BEST Arabidopsis thaliana protein match is: ubiquitin activating enzyme 2 (TAIR:AT5G06460.1); Has 19490 Blast hits to 12603 proteins in 2346 species: Archae - 393; Bacteria - 11015; Metazoa - 2131; Fungi - 1366; Plants - 791; Viruses - 0; Other Eukaryotes - 3794 (source: NCBI BLink). & (p31252|ube13_wheat : 248.0) Ubiquitin-activating enzyme E1 3 - Triticum aestivum (Wheat) & (reliability: 502.0) & (original description: no original description)
Expression Profile
Attention: This gene has low abundance.
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Co-expression Networks
Type | Description | Actions |
Neighborhood | Pseudotsuga release: PSME_00007496-RA | |
Cluster | HCCA clusters: Cluster_131 | |
Functional Annotation
Type | GO Term | Name | Evidence | Source |
MF | GO:0003674 | molecular_function | None | Extended |
MF | GO:0003824 | catalytic activity | None | Extended |
MF | GO:0008641 | ubiquitin-like modifier activating enzyme activity | IEA | InterProScan predictions |
MF | GO:0016874 | ligase activity | None | Extended |
MF | GO:0016877 | ligase activity, forming carbon-sulfur bonds | None | Extended |
Type | GO Term | Name | Evidence | Source |
MF | GO:0004144 | diacylglycerol O-acyltransferase activity | IEP | Predicted GO |
BP | GO:0006364 | rRNA processing | IEP | Predicted GO |
MF | GO:0008374 | O-acyltransferase activity | IEP | Predicted GO |
MF | GO:0008536 | Ran GTPase binding | IEP | Predicted GO |
BP | GO:0016072 | rRNA metabolic process | IEP | Predicted GO |
MF | GO:0016411 | acylglycerol O-acyltransferase activity | IEP | Predicted GO |
MF | GO:0017016 | Ras GTPase binding | IEP | Predicted GO |
MF | GO:0019899 | enzyme binding | IEP | Predicted GO |
CC | GO:0030684 | preribosome | IEP | Predicted GO |
MF | GO:0031267 | small GTPase binding | IEP | Predicted GO |
CC | GO:0032040 | small-subunit processome | IEP | Predicted GO |
BP | GO:0034470 | ncRNA processing | IEP | Predicted GO |
BP | GO:0045017 | glycerolipid biosynthetic process | IEP | Predicted GO |
BP | GO:0046486 | glycerolipid metabolic process | IEP | Predicted GO |
MF | GO:0051020 | GTPase binding | IEP | Predicted GO |
MF | GO:0051087 | chaperone binding | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
IPR000594 | ThiF_NAD_FAD-bd | 230 | 387 |