PSME_00007496-RA


Description : (at2g30110 : 251.0) Encodes a ubiquitin-activating enzyme (E1), involved in the first step in conjugating multiple ubiquitins to proteins targeted for degradation. Gene is expressed in most tissues examined. Mutant is able to revert the constitutive defense responses phenotype of snc1, which indicates the gene is involved in defense response. It also indicates that ubiquitination plays a role in plant defense signalling.; ubiquitin-activating enzyme 1 (UBA1); FUNCTIONS IN: ubiquitin-protein ligase activity, ubiquitin activating enzyme activity; INVOLVED IN: response to cadmium ion, response to other organism, protein ubiquitination, ubiquitin-dependent protein catabolic process; LOCATED IN: plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ubiquitin-activating enzyme, E1, active site (InterPro:IPR018074), Ubiquitin-activating enzyme, E1 (InterPro:IPR018075), Ubiquitin-activating enzyme e1, C-terminal (InterPro:IPR018965), Ubiquitin-activating enzyme repeat (InterPro:IPR000127), Ubiquitin-activating enzyme (InterPro:IPR019572), UBA/THIF-type NAD/FAD binding fold (InterPro:IPR000594), Molybdenum cofactor biosynthesis, MoeB (InterPro:IPR009036), NAD(P)-binding domain (InterPro:IPR016040), Ubiquitin-activating enzyme, E1-like (InterPro:IPR000011); BEST Arabidopsis thaliana protein match is: ubiquitin activating enzyme 2 (TAIR:AT5G06460.1); Has 19490 Blast hits to 12603 proteins in 2346 species: Archae - 393; Bacteria - 11015; Metazoa - 2131; Fungi - 1366; Plants - 791; Viruses - 0; Other Eukaryotes - 3794 (source: NCBI BLink). & (p31252|ube13_wheat : 248.0) Ubiquitin-activating enzyme E1 3 - Triticum aestivum (Wheat) & (reliability: 502.0) & (original description: no original description)


Gene families : OG_42_0122306 (Orthogroups_2024-Update) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00007496-RA
Cluster HCCA clusters: Cluster_131


Type GO Term Name Evidence Source
MF GO:0008641 ubiquitin-like modifier activating enzyme activity IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0004144 diacylglycerol O-acyltransferase activity IEP Predicted GO
BP GO:0006364 rRNA processing IEP Predicted GO
MF GO:0008374 O-acyltransferase activity IEP Predicted GO
MF GO:0008536 Ran GTPase binding IEP Predicted GO
BP GO:0016072 rRNA metabolic process IEP Predicted GO
MF GO:0016411 acylglycerol O-acyltransferase activity IEP Predicted GO
MF GO:0017016 Ras GTPase binding IEP Predicted GO
MF GO:0019899 enzyme binding IEP Predicted GO
CC GO:0030684 preribosome IEP Predicted GO
MF GO:0031267 small GTPase binding IEP Predicted GO
CC GO:0032040 small-subunit processome IEP Predicted GO
BP GO:0034470 ncRNA processing IEP Predicted GO
BP GO:0045017 glycerolipid biosynthetic process IEP Predicted GO
BP GO:0046486 glycerolipid metabolic process IEP Predicted GO
MF GO:0051020 GTPase binding IEP Predicted GO
MF GO:0051087 chaperone binding IEP Predicted GO
InterPro domains Description Start Stop
IPR000594 ThiF_NAD_FAD-bd 230 387
No external refs found!