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  5. PSME_00007655-RA

PSME_00007655-RA


Description : (p31251|ube12_wheat : 984.0) Ubiquitin-activating enzyme E1 2 - Triticum aestivum (Wheat) & (at2g30110 : 983.0) Encodes a ubiquitin-activating enzyme (E1), involved in the first step in conjugating multiple ubiquitins to proteins targeted for degradation. Gene is expressed in most tissues examined. Mutant is able to revert the constitutive defense responses phenotype of snc1, which indicates the gene is involved in defense response. It also indicates that ubiquitination plays a role in plant defense signalling.; ubiquitin-activating enzyme 1 (UBA1); FUNCTIONS IN: ubiquitin-protein ligase activity, ubiquitin activating enzyme activity; INVOLVED IN: response to cadmium ion, response to other organism, protein ubiquitination, ubiquitin-dependent protein catabolic process; LOCATED IN: plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ubiquitin-activating enzyme, E1, active site (InterPro:IPR018074), Ubiquitin-activating enzyme, E1 (InterPro:IPR018075), Ubiquitin-activating enzyme e1, C-terminal (InterPro:IPR018965), Ubiquitin-activating enzyme repeat (InterPro:IPR000127), Ubiquitin-activating enzyme (InterPro:IPR019572), UBA/THIF-type NAD/FAD binding fold (InterPro:IPR000594), Molybdenum cofactor biosynthesis, MoeB (InterPro:IPR009036), NAD(P)-binding domain (InterPro:IPR016040), Ubiquitin-activating enzyme, E1-like (InterPro:IPR000011); BEST Arabidopsis thaliana protein match is: ubiquitin activating enzyme 2 (TAIR:AT5G06460.1); Has 19490 Blast hits to 12603 proteins in 2346 species: Archae - 393; Bacteria - 11015; Metazoa - 2131; Fungi - 1366; Plants - 791; Viruses - 0; Other Eukaryotes - 3794 (source: NCBI BLink). & (reliability: 1966.0) & (original description: no original description)


Gene families : OG_42_0001467 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001467_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00007655-RA
Cluster HCCA clusters: Cluster_187

Target Alias Description ECC score Gene Family Method Actions
Glyma.14G196800 No alias ubiquitin activating enzyme 2 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0008641 ubiquitin-like modifier activating enzyme activity IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0003690 double-stranded DNA binding IEP Predicted GO
MF GO:0004126 cytidine deaminase activity IEP Predicted GO
BP GO:0006213 pyrimidine nucleoside metabolic process IEP Predicted GO
BP GO:0006216 cytidine catabolic process IEP Predicted GO
BP GO:0007034 vacuolar transport IEP Predicted GO
BP GO:0007165 signal transduction IEP Predicted GO
BP GO:0009164 nucleoside catabolic process IEP Predicted GO
BP GO:0009972 cytidine deamination IEP Predicted GO
BP GO:0016226 iron-sulfur cluster assembly IEP Predicted GO
MF GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds IEP Predicted GO
MF GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines IEP Predicted GO
MF GO:0019239 deaminase activity IEP Predicted GO
MF GO:0031072 heat shock protein binding IEP Predicted GO
BP GO:0031163 metallo-sulfur cluster assembly IEP Predicted GO
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predicted GO
BP GO:0034656 nucleobase-containing small molecule catabolic process IEP Predicted GO
BP GO:0042454 ribonucleoside catabolic process IEP Predicted GO
MF GO:0043531 ADP binding IEP Predicted GO
BP GO:0046087 cytidine metabolic process IEP Predicted GO
BP GO:0046131 pyrimidine ribonucleoside metabolic process IEP Predicted GO
BP GO:0046133 pyrimidine ribonucleoside catabolic process IEP Predicted GO
BP GO:0046135 pyrimidine nucleoside catabolic process IEP Predicted GO
MF GO:0051082 unfolded protein binding IEP Predicted GO
BP GO:0072527 pyrimidine-containing compound metabolic process IEP Predicted GO
BP GO:0072529 pyrimidine-containing compound catabolic process IEP Predicted GO
BP GO:1901658 glycosyl compound catabolic process IEP Predicted GO
InterPro domains Description Start Stop
IPR019572 UBA_E1_Cys 482 739
IPR000594 ThiF_NAD_FAD-bd 29 276
IPR018965 Ub-activating_enz_E1_C 809 898
IPR032420 E1_4HB 138 207
IPR000594 ThiF_NAD_FAD-bd 294 798
No external refs found!