PSME_00007980-RA


Description : (at2g36490 : 147.0) A repressor of transcriptional gene silencing. Functions by demethylating the target promoter DNA. Interacts physically with RPA2/ROR1. In the ros1 mutants, an increase in methylation is observed in a number of gene promoters. Among the loci affected by ros1, a few (RD29A and At1g76930) are affected in cytosine methylation in all sequence contexts (CpG, CpNpG or CpNpN), although many others are affected primarily in non-CpG contexts.; demeter-like 1 (DML1); FUNCTIONS IN: protein binding, DNA N-glycosylase activity, DNA-(apurinic or apyrimidinic site) lyase activity; INVOLVED IN: DNA repair, chromatin silencing, negative regulation of chromatin silencing, DNA methylation, DNA demethylation; LOCATED IN: nucleus; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA glycosylase (InterPro:IPR011257), Endonuclease III-like, iron-sulphur cluster loop motif (InterPro:IPR003651), HhH-GPD domain (InterPro:IPR003265); BEST Arabidopsis thaliana protein match is: HhH-GPD base excision DNA repair family protein (TAIR:AT5G04560.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 280.0) & (original description: no original description)


Gene families : OG_42_0001291 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001291_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00007980-RA

Target Alias Description ECC score Gene Family Method Actions
HORVU3Hr1G003060.16 No alias methylcytosine-specific DNA glycosylase *(ROS1) 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source
BP GO:0006855 drug transmembrane transport IEP Predicted GO
MF GO:0008134 transcription factor binding IEP Predicted GO
MF GO:0008168 methyltransferase activity IEP Predicted GO
MF GO:0015238 drug transmembrane transporter activity IEP Predicted GO
MF GO:0015291 secondary active transmembrane transporter activity IEP Predicted GO
MF GO:0015297 antiporter activity IEP Predicted GO
BP GO:0015893 drug transport IEP Predicted GO
MF GO:0016740 transferase activity IEP Predicted GO
MF GO:0016741 transferase activity, transferring one-carbon groups IEP Predicted GO
MF GO:0017025 TBP-class protein binding IEP Predicted GO

No InterPro domains available for this sequence

No external refs found!