PSME_00008139-RA


Description : (p31685|4cl2_soltu : 666.0) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2) (4-coumaroyl-CoA synthase 2) - Solanum tuberosum (Potato) & (at3g21240 : 638.0) encodes an isoform of 4-coumarate:CoA ligase (4CL), which is involved in the last step of the general phenylpropanoid pathway. The catalytic efficiency was in the following (descending) order: p-coumaric acid, caffeic acid, ferulic acid, 5-OH-ferulic acid and cinnamic acid. At4CL2 was unable to use sinapic acid as substrate.; 4-coumarate:CoA ligase 2 (4CL2); CONTAINS InterPro DOMAIN/s: AMP-binding, conserved site (InterPro:IPR020845), AMP-dependent synthetase/ligase (InterPro:IPR000873); BEST Arabidopsis thaliana protein match is: 4-coumarate:CoA ligase 1 (TAIR:AT1G51680.1); Has 86092 Blast hits to 78635 proteins in 3758 species: Archae - 1209; Bacteria - 54193; Metazoa - 3597; Fungi - 4717; Plants - 2816; Viruses - 1; Other Eukaryotes - 19559 (source: NCBI BLink). & (reliability: 1276.0) & (original description: no original description)


Gene families : OG_42_0000133 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000133_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00008139-RA
Cluster HCCA clusters: Cluster_259

Target Alias Description ECC score Gene Family Method Actions
173133 No alias 4-coumarate:CoA ligase 3 0.02 Orthogroups_2024-Update
181279 No alias AMP-dependent synthetase and ligase family protein 0.02 Orthogroups_2024-Update
A4A49_15235 No alias 4-coumarate--coa ligase 2 0.04 Orthogroups_2024-Update
At1g20510 No alias 4-coumarate--CoA ligase-like 5... 0.03 Orthogroups_2024-Update
Bradi3g37300 No alias 4-coumarate:CoA ligase 2 0.03 Orthogroups_2024-Update
Brara.G02592.1 No alias p-coumarate 0.03 Orthogroups_2024-Update
Brara.H02328.1 No alias OPC-8 0.04 Orthogroups_2024-Update
PSME_00013808-RA No alias (at1g20510 : 243.0) OPC-8:0 CoA ligase1 (OPCL1);... 0.04 Orthogroups_2024-Update
PSME_00019639-RA No alias (at1g20510 : 494.0) OPC-8:0 CoA ligase1 (OPCL1);... 0.04 Orthogroups_2024-Update
PSME_00022570-RA No alias (at1g62940 : 648.0) encodes an acyl-CoA synthetase, has... 0.05 Orthogroups_2024-Update
Pp1s12_59V6 No alias amp dependent 0.02 Orthogroups_2024-Update
Sobic.004G062500.1 No alias p-coumarate 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA InterProScan predictions
Type GO Term Name Evidence Source
BP GO:0000096 sulfur amino acid metabolic process IEP Predicted GO
BP GO:0000097 sulfur amino acid biosynthetic process IEP Predicted GO
MF GO:0003871 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity IEP Predicted GO
MF GO:0004519 endonuclease activity IEP Predicted GO
MF GO:0004521 endoribonuclease activity IEP Predicted GO
MF GO:0004523 RNA-DNA hybrid ribonuclease activity IEP Predicted GO
MF GO:0004540 ribonuclease activity IEP Predicted GO
MF GO:0005507 copper ion binding IEP Predicted GO
BP GO:0006082 organic acid metabolic process IEP Predicted GO
BP GO:0006520 cellular amino acid metabolic process IEP Predicted GO
BP GO:0006555 methionine metabolic process IEP Predicted GO
BP GO:0006629 lipid metabolic process IEP Predicted GO
BP GO:0006790 sulfur compound metabolic process IEP Predicted GO
MF GO:0008061 chitin binding IEP Predicted GO
MF GO:0008172 S-methyltransferase activity IEP Predicted GO
BP GO:0008652 cellular amino acid biosynthetic process IEP Predicted GO
BP GO:0009066 aspartate family amino acid metabolic process IEP Predicted GO
BP GO:0009067 aspartate family amino acid biosynthetic process IEP Predicted GO
BP GO:0009086 methionine biosynthetic process IEP Predicted GO
BP GO:0009690 cytokinin metabolic process IEP Predicted GO
BP GO:0010817 regulation of hormone levels IEP Predicted GO
BP GO:0016053 organic acid biosynthetic process IEP Predicted GO
MF GO:0016491 oxidoreductase activity IEP Predicted GO
MF GO:0016787 hydrolase activity IEP Predicted GO
MF GO:0016788 hydrolase activity, acting on ester bonds IEP Predicted GO
MF GO:0016790 thiolester hydrolase activity IEP Predicted GO
MF GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters IEP Predicted GO
MF GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters IEP Predicted GO
MF GO:0019139 cytokinin dehydrogenase activity IEP Predicted GO
BP GO:0019752 carboxylic acid metabolic process IEP Predicted GO
MF GO:0020037 heme binding IEP Predicted GO
BP GO:0034754 cellular hormone metabolic process IEP Predicted GO
MF GO:0042085 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity IEP Predicted GO
BP GO:0042445 hormone metabolic process IEP Predicted GO
MF GO:0043169 cation binding IEP Predicted GO
BP GO:0043436 oxoacid metabolic process IEP Predicted GO
BP GO:0044272 sulfur compound biosynthetic process IEP Predicted GO
BP GO:0044281 small molecule metabolic process IEP Predicted GO
BP GO:0044283 small molecule biosynthetic process IEP Predicted GO
BP GO:0046394 carboxylic acid biosynthetic process IEP Predicted GO
MF GO:0046872 metal ion binding IEP Predicted GO
MF GO:0046906 tetrapyrrole binding IEP Predicted GO
MF GO:0046914 transition metal ion binding IEP Predicted GO
MF GO:0048037 cofactor binding IEP Predicted GO
BP GO:0055114 oxidation-reduction process IEP Predicted GO
BP GO:1901605 alpha-amino acid metabolic process IEP Predicted GO
BP GO:1901607 alpha-amino acid biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR025110 AMP-bd_C 453 528
IPR000873 AMP-dep_Synth/Lig 34 444
No external refs found!