PSME_00008207-RA


Description : (p02276|h2a2_wheat : 135.0) Histone H2A.2.1 - Triticum aestivum (Wheat) & (at1g08880 : 129.0) Encodes HTA5, a histone H2A protein. H2AX is a meiosis-specific isoform of histone H2A. Upon DSB formation, rapid accumulation of phosphorylated H2AX (γ-H2AX) occurs around the break site. H2AX foci accumulate in early G2. Immunolocalization studies in spread preparations of wild-type meiocytes at G2/early leptotene revealed the accumulation of numerous rather diffuse γ-H2AX foci throughout the chromatin. However, their accumulation is not contemporaneous with that of AtSPO11-1. At 3 h post-S, no γ-H2AX foci are detected. During the 3- to 5-h window when AtSPO11-1 foci rapidly disappear, there is an equally swift accumulation of γ-H2AX to a maximum of >50 diffuse foci. The level of γH2AX then remains constant for a further 13 h before undergoing a gradual decrease to 10ñ20 foci in the 18- to 24-h post-S period. By 30 h the foci have disappeared from the chromatin.; H2AXA; FUNCTIONS IN: DNA binding; INVOLVED IN: nucleosome assembly; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histone H2A (InterPro:IPR002119), Histone-fold (InterPro:IPR009072), Histone core (InterPro:IPR007125); BEST Arabidopsis thaliana protein match is: gamma histone variant H2AX (TAIR:AT1G54690.1); Has 3916 Blast hits to 3911 proteins in 363 species: Archae - 0; Bacteria - 0; Metazoa - 2550; Fungi - 318; Plants - 612; Viruses - 4; Other Eukaryotes - 432 (source: NCBI BLink). & (reliability: 258.0) & (original description: no original description)


Gene families : OG_42_0000138 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000138_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00008207-RA
Cluster HCCA clusters: Cluster_163

Target Alias Description ECC score Gene Family Method Actions
170948 No alias Histone superfamily protein 0.02 Orthogroups_2024-Update
A4A49_30810 No alias histone h2ax 0.02 Orthogroups_2024-Update
Bradi1g25390 No alias histone H2A 10 0.03 Orthogroups_2024-Update
Cre06.g264950 No alias histone H2A 10 0.04 Orthogroups_2024-Update
Cre06.g265350 No alias histone H2A 10 0.04 Orthogroups_2024-Update
Cre06.g268050 No alias histone H2A 10 0.03 Orthogroups_2024-Update
Cre06.g268300 No alias histone H2A 10 0.08 Orthogroups_2024-Update
Cre06.g274200 No alias histone H2A 10 0.05 Orthogroups_2024-Update
Cre06.g275850 No alias histone H2A 10 0.02 Orthogroups_2024-Update
Cre12.g505550 No alias histone H2A 10 0.02 Orthogroups_2024-Update
Cre12.g506250 No alias histone H2A 10 0.04 Orthogroups_2024-Update
Cre13.g570100 No alias histone H2A 10 0.11 Orthogroups_2024-Update
Cre17.g708550 No alias histone H2A 10 0.02 Orthogroups_2024-Update
Cre17.g709200 No alias histone H2A 10 0.03 Orthogroups_2024-Update
Cre17.g711700 No alias histone H2A 10 0.05 Orthogroups_2024-Update
Cre17.g713400 No alias histone H2A 10 0.02 Orthogroups_2024-Update
GRMZM2G041381 No alias histone H2A 2 0.03 Orthogroups_2024-Update
GRMZM2G109448 No alias histone H2A 12 0.02 Orthogroups_2024-Update
GRMZM2G151726 No alias histone H2A 2 0.03 Orthogroups_2024-Update
GRMZM2G151826 No alias histone H2A 2 0.02 Orthogroups_2024-Update
Glyma.03G148100 No alias Histone superfamily protein 0.03 Orthogroups_2024-Update
Glyma.12G215500 No alias histone H2A 10 0.03 Orthogroups_2024-Update
Glyma.15G040400 No alias histone H2A 12 0.03 Orthogroups_2024-Update
HORVU1Hr1G005870.1 No alias histone *(H2A) 0.02 Orthogroups_2024-Update
HORVU6Hr1G006140.1 No alias histone *(H2A) 0.03 Orthogroups_2024-Update
HORVU6Hr1G021160.1 No alias histone *(H2A) 0.03 Orthogroups_2024-Update
HORVU6Hr1G021260.2 No alias histone *(H2A) 0.04 Orthogroups_2024-Update
HORVU7Hr1G100100.3 No alias histone *(H2A) 0.05 Orthogroups_2024-Update
HORVU7Hr1G100110.4 No alias histone *(H2A) 0.05 Orthogroups_2024-Update
HORVU7Hr1G100120.13 No alias histone *(H2A) 0.03 Orthogroups_2024-Update
HORVU7Hr1G112470.1 No alias histone *(H2A) 0.02 Orthogroups_2024-Update
Kfl00099_g21 kfl00099_g21_v1.1 (q2qpg9|h2axb_orysa : 166.0) Probable histone H2AXb -... 0.02 Orthogroups_2024-Update
Kfl00125_0190 kfl00125_0190_v1.1 (p50567|h2a_chlre : 169.0) Histone H2A - Chlamydomonas... 0.01 Orthogroups_2024-Update
LOC_Os07g36140 No alias core histone H2A/H2B/H3/H4, putative, expressed 0.02 Orthogroups_2024-Update
MA_10426943g0010 No alias (p50567|h2a_chlre : 132.0) Histone H2A - Chlamydomonas... 0.05 Orthogroups_2024-Update
MA_191819g0010 No alias (at4g27230 : 166.0) Encodes HTA2, a histone H2A... 0.04 Orthogroups_2024-Update
MA_22203g0020 No alias (at5g54640 : 145.0) Isolated from T-DNA insertion line,... 0.04 Orthogroups_2024-Update
MA_7320190g0010 No alias (p19177|h2a_petcr : 149.0) Histone H2A - Petroselinum... 0.03 Orthogroups_2024-Update
Mp2g00760.1 No alias histone (H2A) 0.02 Orthogroups_2024-Update
PSME_00050693-RA No alias (at4g27230 : 166.0) Encodes HTA2, a histone H2A... 0.09 Orthogroups_2024-Update
Pp1s72_86V6 No alias histone h2a 0.04 Orthogroups_2024-Update
Seita.5G370700.1 No alias histone *(H2A) 0.04 Orthogroups_2024-Update
Sobic.001G416800.1 No alias histone *(H2A) 0.03 Orthogroups_2024-Update
Sobic.001G416900.1 No alias histone *(H2A) 0.06 Orthogroups_2024-Update
Sobic.002G330000.1 No alias histone *(H2A) 0.03 Orthogroups_2024-Update
Solyc01g099410 No alias Histone H2A (AHRD V3.3 *** G8IIJ5_SOLLC) 0.03 Orthogroups_2024-Update
Solyc09g074300 No alias Histone H2A (AHRD V3.3 *** K4CV07_SOLLC) 0.03 Orthogroups_2024-Update
Solyc09g082710 No alias Histone H2A (AHRD V3.3 *** K4CVP7_SOLLC) 0.03 Orthogroups_2024-Update
Solyc10g006560 No alias Histone H2A (AHRD V3.3 *** A0A0V0H7M3_SOLCH) 0.03 Orthogroups_2024-Update
Solyc11g073250 No alias Histone H2A (AHRD V3.3 *** K4DB31_SOLLC) 0.03 Orthogroups_2024-Update
Solyc11g073260 No alias Histone H2A (AHRD V3.3 *** K4DB32_SOLLC) 0.03 Orthogroups_2024-Update
Solyc12g005270 No alias Histone H2A (AHRD V3.3 *** K4DB65_SOLLC) 0.03 Orthogroups_2024-Update
Sopen01g042970 No alias Core histone H2A/H2B/H3/H4 0.03 Orthogroups_2024-Update
Sopen09g005140 No alias Core histone H2A/H2B/H3/H4 0.02 Orthogroups_2024-Update
Sopen09g029130 No alias Core histone H2A/H2B/H3/H4 0.06 Orthogroups_2024-Update
Sopen09g031570 No alias Core histone H2A/H2B/H3/H4 0.04 Orthogroups_2024-Update
Sopen10g002510 No alias Core histone H2A/H2B/H3/H4 0.04 Orthogroups_2024-Update
Sopen11g030890 No alias Core histone H2A/H2B/H3/H4 0.02 Orthogroups_2024-Update
evm.model.contig_533.4 No alias (p16866|h2a4_volca : 182.0) Histone H2A-IV - Volvox... 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
CC GO:0000786 nucleosome IEA InterProScan predictions
MF GO:0003677 DNA binding IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0005216 ion channel activity IEP Predicted GO
MF GO:0005244 voltage-gated ion channel activity IEP Predicted GO
MF GO:0005247 voltage-gated chloride channel activity IEP Predicted GO
MF GO:0005253 anion channel activity IEP Predicted GO
MF GO:0005254 chloride channel activity IEP Predicted GO
BP GO:0006325 chromatin organization IEP Predicted GO
BP GO:0006334 nucleosome assembly IEP Predicted GO
BP GO:0006820 anion transport IEP Predicted GO
BP GO:0006821 chloride transport IEP Predicted GO
MF GO:0008308 voltage-gated anion channel activity IEP Predicted GO
MF GO:0008509 anion transmembrane transporter activity IEP Predicted GO
MF GO:0015103 inorganic anion transmembrane transporter activity IEP Predicted GO
MF GO:0015108 chloride transmembrane transporter activity IEP Predicted GO
BP GO:0015698 inorganic anion transport IEP Predicted GO
BP GO:0022607 cellular component assembly IEP Predicted GO
MF GO:0022832 voltage-gated channel activity IEP Predicted GO
MF GO:0022836 gated channel activity IEP Predicted GO
MF GO:0022838 substrate-specific channel activity IEP Predicted GO
MF GO:0022839 ion gated channel activity IEP Predicted GO
BP GO:0034622 cellular protein-containing complex assembly IEP Predicted GO
BP GO:0034728 nucleosome organization IEP Predicted GO
BP GO:0043933 protein-containing complex subunit organization IEP Predicted GO
BP GO:0065003 protein-containing complex assembly IEP Predicted GO
BP GO:0065004 protein-DNA complex assembly IEP Predicted GO
BP GO:0071824 protein-DNA complex subunit organization IEP Predicted GO
InterPro domains Description Start Stop
IPR032454 Histone_H2A_C 99 132
IPR007125 Histone_H2A/H2B/H3 18 96
No external refs found!