PSME_00008210-RA


Description : (at1g54690 : 107.0) Encodes HTA3, a histone H2A protein. H2AX is a meiosis-specific isoform of histone H2A. Upon DSB formation, rapid accumulation of phosphorylated H2AX (γ-H2AX) occurs around the break site. H2AX foci accumulate in early G2. Immunolocalization studies in spread preparations of wild-type meiocytes at G2/early leptotene revealed the accumulation of numerous rather diffuse γ-H2AX foci throughout the chromatin. However, their accumulation is not contemporaneous with that of AtSPO11-1. At 3 h post-S, no γ-H2AX foci are detected. During the 3- to 5-h window when AtSPO11-1 foci rapidly disappear, there is an equally swift accumulation of γ-H2AX to a maximum of >50 diffuse foci. The level of γH2AX then remains constant for a further 13 h before undergoing a gradual decrease to 10ñ20 foci in the 18- to 24-h post-S period. By 30 h the foci have disappeared from the chromatin.; gamma histone variant H2AX (GAMMA-H2AX); FUNCTIONS IN: DNA binding; INVOLVED IN: nucleosome assembly; LOCATED IN: nucleolus, nucleus; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histone H2A (InterPro:IPR002119), Histone-fold (InterPro:IPR009072), Histone core (InterPro:IPR007125); BEST Arabidopsis thaliana protein match is: Histone superfamily protein (TAIR:AT1G08880.1); Has 3932 Blast hits to 3927 proteins in 364 species: Archae - 0; Bacteria - 0; Metazoa - 2549; Fungi - 335; Plants - 612; Viruses - 4; Other Eukaryotes - 432 (source: NCBI BLink). & (p50567|h2a_chlre : 106.0) Histone H2A - Chlamydomonas reinhardtii & (reliability: 214.0) & (original description: no original description)


Gene families : OG_42_0000138 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000138_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00008210-RA
Cluster HCCA clusters: Cluster_236

Target Alias Description ECC score Gene Family Method Actions
A4A49_30810 No alias histone h2ax 0.04 Orthogroups_2024-Update
At1g51060 No alias Probable histone H2A.1 [Source:UniProtKB/Swiss-Prot;Acc:Q9C681] 0.02 Orthogroups_2024-Update
At5g02560 No alias Histone H2A [Source:UniProtKB/TrEMBL;Acc:F4KCF4] 0.02 Orthogroups_2024-Update
Bradi1g25390 No alias histone H2A 10 0.02 Orthogroups_2024-Update
Cre06.g265350 No alias histone H2A 10 0.03 Orthogroups_2024-Update
Cre06.g268050 No alias histone H2A 10 0.02 Orthogroups_2024-Update
Cre06.g273900 No alias histone H2A 10 0.05 Orthogroups_2024-Update
Cre06.g275850 No alias histone H2A 10 0.02 Orthogroups_2024-Update
Cre12.g504750 No alias histone H2A 10 0.03 Orthogroups_2024-Update
Cre17.g711700 No alias histone H2A 10 0.03 Orthogroups_2024-Update
Cre17.g713400 No alias histone H2A 10 0.02 Orthogroups_2024-Update
GRMZM2G041381 No alias histone H2A 2 0.03 Orthogroups_2024-Update
Glyma.13G333900 No alias histone H2A 12 0.03 Orthogroups_2024-Update
HORVU5Hr1G026650.2 No alias histone *(H2A) 0.02 Orthogroups_2024-Update
HORVU5Hr1G108640.1 No alias histone *(H2A) 0.03 Orthogroups_2024-Update
HORVU6Hr1G006080.2 No alias histone *(H2A) 0.05 Orthogroups_2024-Update
HORVU6Hr1G011490.2 No alias histone *(H2A) 0.05 Orthogroups_2024-Update
HORVU7Hr1G117230.1 No alias histone *(H2A) 0.02 Orthogroups_2024-Update
Kfl00099_g21 kfl00099_g21_v1.1 (q2qpg9|h2axb_orysa : 166.0) Probable histone H2AXb -... 0.02 Orthogroups_2024-Update
MA_191819g0010 No alias (at4g27230 : 166.0) Encodes HTA2, a histone H2A... 0.04 Orthogroups_2024-Update
Mp4g21750.1 No alias histone (H2A) 0.03 Orthogroups_2024-Update
Potri.005G040700 No alias gamma histone variant H2AX 0.03 Orthogroups_2024-Update
Pp1s117_154V6 No alias histone h2a 0.04 Orthogroups_2024-Update
Pp1s55_112V6 No alias histone 2 0.04 Orthogroups_2024-Update
Sopen10g002510 No alias Core histone H2A/H2B/H3/H4 0.03 Orthogroups_2024-Update
evm.model.contig_533.4 No alias (p16866|h2a4_volca : 182.0) Histone H2A-IV - Volvox... 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
CC GO:0000786 nucleosome IEA InterProScan predictions
MF GO:0003677 DNA binding IEA InterProScan predictions
Type GO Term Name Evidence Source
BP GO:0006508 proteolysis IEP Predicted GO
BP GO:0006720 isoprenoid metabolic process IEP Predicted GO
BP GO:0006721 terpenoid metabolic process IEP Predicted GO
BP GO:0006811 ion transport IEP Predicted GO
BP GO:0006812 cation transport IEP Predicted GO
MF GO:0008097 5S rRNA binding IEP Predicted GO
MF GO:0008233 peptidase activity IEP Predicted GO
MF GO:0008236 serine-type peptidase activity IEP Predicted GO
BP GO:0008299 isoprenoid biosynthetic process IEP Predicted GO
MF GO:0008661 1-deoxy-D-xylulose-5-phosphate synthase activity IEP Predicted GO
BP GO:0016114 terpenoid biosynthetic process IEP Predicted GO
MF GO:0016744 transferase activity, transferring aldehyde or ketonic groups IEP Predicted GO
MF GO:0016758 transferase activity, transferring hexosyl groups IEP Predicted GO
MF GO:0017171 serine hydrolase activity IEP Predicted GO
MF GO:0019843 rRNA binding IEP Predicted GO
BP GO:0030001 metal ion transport IEP Predicted GO
MF GO:0070011 peptidase activity, acting on L-amino acid peptides IEP Predicted GO
InterPro domains Description Start Stop
IPR007125 Histone_H2A/H2B/H3 103 206
IPR032454 Histone_H2A_C 209 242
No external refs found!