Description : (at1g54690 : 107.0) Encodes HTA3, a histone H2A protein. H2AX is a meiosis-specific isoform of histone H2A. Upon DSB formation, rapid accumulation of phosphorylated H2AX (γ-H2AX) occurs around the break site. H2AX foci accumulate in early G2. Immunolocalization studies in spread preparations of wild-type meiocytes at G2/early leptotene revealed the accumulation of numerous rather diffuse γ-H2AX foci throughout the chromatin. However, their accumulation is not contemporaneous with that of AtSPO11-1. At 3 h post-S, no γ-H2AX foci are detected. During the 3- to 5-h window when AtSPO11-1 foci rapidly disappear, there is an equally swift accumulation of γ-H2AX to a maximum of >50 diffuse foci. The level of γH2AX then remains constant for a further 13 h before undergoing a gradual decrease to 10ñ20 foci in the 18- to 24-h post-S period. By 30 h the foci have disappeared from the chromatin.; gamma histone variant H2AX (GAMMA-H2AX); FUNCTIONS IN: DNA binding; INVOLVED IN: nucleosome assembly; LOCATED IN: nucleolus, nucleus; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histone H2A (InterPro:IPR002119), Histone-fold (InterPro:IPR009072), Histone core (InterPro:IPR007125); BEST Arabidopsis thaliana protein match is: Histone superfamily protein (TAIR:AT1G08880.1); Has 3932 Blast hits to 3927 proteins in 364 species: Archae - 0; Bacteria - 0; Metazoa - 2549; Fungi - 335; Plants - 612; Viruses - 4; Other Eukaryotes - 432 (source: NCBI BLink). & (p50567|h2a_chlre : 106.0) Histone H2A - Chlamydomonas reinhardtii & (reliability: 214.0) & (original description: no original description)
Gene families : OG_42_0000138 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000138_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00008210-RA | |
Cluster | HCCA clusters: Cluster_236 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
A4A49_30810 | No alias | histone h2ax | 0.04 | Orthogroups_2024-Update | |
At1g51060 | No alias | Probable histone H2A.1 [Source:UniProtKB/Swiss-Prot;Acc:Q9C681] | 0.02 | Orthogroups_2024-Update | |
At5g02560 | No alias | Histone H2A [Source:UniProtKB/TrEMBL;Acc:F4KCF4] | 0.02 | Orthogroups_2024-Update | |
Bradi1g25390 | No alias | histone H2A 10 | 0.02 | Orthogroups_2024-Update | |
Cre06.g265350 | No alias | histone H2A 10 | 0.03 | Orthogroups_2024-Update | |
Cre06.g268050 | No alias | histone H2A 10 | 0.02 | Orthogroups_2024-Update | |
Cre06.g273900 | No alias | histone H2A 10 | 0.05 | Orthogroups_2024-Update | |
Cre06.g275850 | No alias | histone H2A 10 | 0.02 | Orthogroups_2024-Update | |
Cre12.g504750 | No alias | histone H2A 10 | 0.03 | Orthogroups_2024-Update | |
Cre17.g711700 | No alias | histone H2A 10 | 0.03 | Orthogroups_2024-Update | |
Cre17.g713400 | No alias | histone H2A 10 | 0.02 | Orthogroups_2024-Update | |
GRMZM2G041381 | No alias | histone H2A 2 | 0.03 | Orthogroups_2024-Update | |
Glyma.13G333900 | No alias | histone H2A 12 | 0.03 | Orthogroups_2024-Update | |
HORVU5Hr1G026650.2 | No alias | histone *(H2A) | 0.02 | Orthogroups_2024-Update | |
HORVU5Hr1G108640.1 | No alias | histone *(H2A) | 0.03 | Orthogroups_2024-Update | |
HORVU6Hr1G006080.2 | No alias | histone *(H2A) | 0.05 | Orthogroups_2024-Update | |
HORVU6Hr1G011490.2 | No alias | histone *(H2A) | 0.05 | Orthogroups_2024-Update | |
HORVU7Hr1G117230.1 | No alias | histone *(H2A) | 0.02 | Orthogroups_2024-Update | |
Kfl00099_g21 | kfl00099_g21_v1.1 | (q2qpg9|h2axb_orysa : 166.0) Probable histone H2AXb -... | 0.02 | Orthogroups_2024-Update | |
MA_191819g0010 | No alias | (at4g27230 : 166.0) Encodes HTA2, a histone H2A... | 0.04 | Orthogroups_2024-Update | |
Mp4g21750.1 | No alias | histone (H2A) | 0.03 | Orthogroups_2024-Update | |
Potri.005G040700 | No alias | gamma histone variant H2AX | 0.03 | Orthogroups_2024-Update | |
Pp1s117_154V6 | No alias | histone h2a | 0.04 | Orthogroups_2024-Update | |
Pp1s55_112V6 | No alias | histone 2 | 0.04 | Orthogroups_2024-Update | |
Sopen10g002510 | No alias | Core histone H2A/H2B/H3/H4 | 0.03 | Orthogroups_2024-Update | |
evm.model.contig_533.4 | No alias | (p16866|h2a4_volca : 182.0) Histone H2A-IV - Volvox... | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
CC | GO:0000786 | nucleosome | IEA | InterProScan predictions |
MF | GO:0003677 | DNA binding | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0006508 | proteolysis | IEP | Predicted GO |
BP | GO:0006720 | isoprenoid metabolic process | IEP | Predicted GO |
BP | GO:0006721 | terpenoid metabolic process | IEP | Predicted GO |
BP | GO:0006811 | ion transport | IEP | Predicted GO |
BP | GO:0006812 | cation transport | IEP | Predicted GO |
MF | GO:0008097 | 5S rRNA binding | IEP | Predicted GO |
MF | GO:0008233 | peptidase activity | IEP | Predicted GO |
MF | GO:0008236 | serine-type peptidase activity | IEP | Predicted GO |
BP | GO:0008299 | isoprenoid biosynthetic process | IEP | Predicted GO |
MF | GO:0008661 | 1-deoxy-D-xylulose-5-phosphate synthase activity | IEP | Predicted GO |
BP | GO:0016114 | terpenoid biosynthetic process | IEP | Predicted GO |
MF | GO:0016744 | transferase activity, transferring aldehyde or ketonic groups | IEP | Predicted GO |
MF | GO:0016758 | transferase activity, transferring hexosyl groups | IEP | Predicted GO |
MF | GO:0017171 | serine hydrolase activity | IEP | Predicted GO |
MF | GO:0019843 | rRNA binding | IEP | Predicted GO |
BP | GO:0030001 | metal ion transport | IEP | Predicted GO |
MF | GO:0070011 | peptidase activity, acting on L-amino acid peptides | IEP | Predicted GO |
No external refs found! |