Description : (q8w013|comt1_catro : 225.0) Caffeic acid 3-O-methyltransferase (EC 2.1.1.68) (S-adenosysl-L-methionine:caffeic acid 3-O-methyltransferase) (COMT) (CAOMT) - Catharanthus roseus (Rosy periwinkle) (Madagascar periwinkle) & (at5g54160 : 217.0) A caffeic acid/5-hydroxyferulic acid O-methyltransferase. Interacts with 14-4-3 proteins in yeast 2 hybrid assay. AtOMT1 (At5g54160) encodes a flavonol 3Ã-O-methyltransferase that is highly active towards quercetin and myricetin. The substrate specificity identifies the enzyme as flavonol 3Ã-methyltransferase which replaces the former annotation of the gene to encode a caffeic acid/5-hydroxyferulic acid O-methyltransferase; O-methyltransferase 1 (OMT1); FUNCTIONS IN: myricetin 3'-O-methyltransferase activity, quercetin 3-O-methyltransferase activity, caffeate O-methyltransferase activity; INVOLVED IN: lignin biosynthetic process, flavonol biosynthetic process; LOCATED IN: cytosol, nucleus, plasma membrane, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Plant methyltransferase dimerisation (InterPro:IPR012967), O-methyltransferase, family 2 (InterPro:IPR001077), O-methyltransferase, COMT, eukaryota (InterPro:IPR016461); BEST Arabidopsis thaliana protein match is: O-methyltransferase family protein (TAIR:AT1G77520.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 434.0) & (original description: no original description)
Gene families : OG_42_0000016 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000016_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00008877-RA | |
Cluster | HCCA clusters: Cluster_53 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
A4A49_32756 | No alias | trans-resveratrol di-o-methyltransferase | 0.05 | Orthogroups_2024-Update | |
At1g76790 | No alias | Indole glucosinolate O-methyltransferase 5... | 0.02 | Orthogroups_2024-Update | |
GRMZM2G408458 | No alias | O-methyltransferase family protein | 0.04 | Orthogroups_2024-Update | |
HORVU6Hr1G092840.2 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
LOC_Os07g27970 | No alias | O-methyltransferase, putative, expressed | 0.02 | Orthogroups_2024-Update | |
LOC_Os10g02840 | No alias | O-methyltransferase, putative, expressed | 0.02 | Orthogroups_2024-Update | |
Mp2g07390.1 | No alias | Enzyme classification.EC_2 transferases.EC_2.1... | 0.02 | Orthogroups_2024-Update | |
PSME_00037447-RA | No alias | (q8w013|comt1_catro : 270.0) Caffeic acid... | 0.04 | Orthogroups_2024-Update | |
Potri.001G451100 | No alias | O-methyltransferase 1 | 0.04 | Orthogroups_2024-Update | |
Potri.013G122500 | No alias | O-methyltransferase family protein | 0.02 | Orthogroups_2024-Update | |
Seita.3G179100.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
Seita.6G148100.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
Seita.6G174800.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.04 | Orthogroups_2024-Update | |
Seita.8G093200.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.04 | Orthogroups_2024-Update | |
Sobic.004G341500.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.05 | Orthogroups_2024-Update | |
Sobic.009G198000.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
Solyc10g047520 | No alias | LOW QUALITY:O-methyltransferase (AHRD V3.3 *-* Q6VMV7_MENPI) | 0.04 | Orthogroups_2024-Update | |
Sopen03g028450 | No alias | O-methyltransferase | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0008171 | O-methyltransferase activity | IEA | InterProScan predictions |
MF | GO:0046983 | protein dimerization activity | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0006629 | lipid metabolic process | IEP | Predicted GO |
MF | GO:0008134 | transcription factor binding | IEP | Predicted GO |
BP | GO:0016197 | endosomal transport | IEP | Predicted GO |
BP | GO:0016482 | cytosolic transport | IEP | Predicted GO |
MF | GO:0017025 | TBP-class protein binding | IEP | Predicted GO |
CC | GO:0030906 | retromer, cargo-selective complex | IEP | Predicted GO |
BP | GO:0042147 | retrograde transport, endosome to Golgi | IEP | Predicted GO |
No external refs found! |