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  5. PSME_00009133-RA

PSME_00009133-RA


Description : (at1g48050 : 180.0) Ku80 and ku70 form the heterodimer complex Ku, required for proper maintenance of the telomeric C strand. Ku regulates the extension of the telomeric G strand. Interacts with WEX, and this interaction stimulates the WEX exonuclease activity. Binds double stranded DNA breaks as a heterodimer with Ku70, involved in non-homologous end joining repair. Mutants are defective in T-DNA integration. Over expression confers increased resistance to DNA damage agents and increased susceptibility to T-DNA transformation.; KU80; FUNCTIONS IN: double-stranded DNA binding, protein binding; INVOLVED IN: in 6 processes; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ku70/Ku80, N-terminal alpha/beta (InterPro:IPR005161), DNA helicase, ATP-dependent, Ku type (InterPro:IPR006164), Spen Paralogue and Orthologue SPOC, C-terminal-like (InterPro:IPR016194), Ku70/Ku80 C-terminal arm (InterPro:IPR005160), Ku, C-terminal (InterPro:IPR014893); Has 786 Blast hits to 750 proteins in 217 species: Archae - 0; Bacteria - 40; Metazoa - 246; Fungi - 345; Plants - 62; Viruses - 0; Other Eukaryotes - 93 (source: NCBI BLink). & (reliability: 360.0) & (original description: no original description)


Gene families : OG_42_0001893 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001893_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00009133-RA
Cluster HCCA clusters: Cluster_231

Target Alias Description ECC score Gene Family Method Actions
Kfl00233_0160 kfl00233_0160_v1.1 (at1g48050 : 433.0) Ku80 and ku70 form the heterodimer... 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0016817 hydrolase activity, acting on acid anhydrides IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0000049 tRNA binding IEP Predicted GO
MF GO:0000166 nucleotide binding IEP Predicted GO
BP GO:0000726 non-recombinational repair IEP Predicted GO
MF GO:0003677 DNA binding IEP Predicted GO
MF GO:0003779 actin binding IEP Predicted GO
MF GO:0004506 squalene monooxygenase activity IEP Predicted GO
MF GO:0004672 protein kinase activity IEP Predicted GO
MF GO:0005096 GTPase activator activity IEP Predicted GO
MF GO:0005488 binding IEP Predicted GO
MF GO:0005515 protein binding IEP Predicted GO
BP GO:0006281 DNA repair IEP Predicted GO
BP GO:0006302 double-strand break repair IEP Predicted GO
BP GO:0006303 double-strand break repair via nonhomologous end joining IEP Predicted GO
BP GO:0006464 cellular protein modification process IEP Predicted GO
BP GO:0006468 protein phosphorylation IEP Predicted GO
BP GO:0006793 phosphorus metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
BP GO:0006974 cellular response to DNA damage stimulus IEP Predicted GO
BP GO:0007010 cytoskeleton organization IEP Predicted GO
MF GO:0008047 enzyme activator activity IEP Predicted GO
BP GO:0009987 cellular process IEP Predicted GO
MF GO:0016301 kinase activity IEP Predicted GO
MF GO:0016307 phosphatidylinositol phosphate kinase activity IEP Predicted GO
BP GO:0016310 phosphorylation IEP Predicted GO
MF GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity IEP Predicted GO
MF GO:0016772 transferase activity, transferring phosphorus-containing groups IEP Predicted GO
MF GO:0016773 phosphotransferase activity, alcohol group as acceptor IEP Predicted GO
MF GO:0019207 kinase regulator activity IEP Predicted GO
MF GO:0019887 protein kinase regulator activity IEP Predicted GO
MF GO:0030234 enzyme regulator activity IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
MF GO:0030695 GTPase regulator activity IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
BP GO:0033554 cellular response to stress IEP Predicted GO
BP GO:0036211 protein modification process IEP Predicted GO
BP GO:0043170 macromolecule metabolic process IEP Predicted GO
BP GO:0043412 macromolecule modification IEP Predicted GO
MF GO:0043531 ADP binding IEP Predicted GO
BP GO:0044237 cellular metabolic process IEP Predicted GO
BP GO:0044260 cellular macromolecule metabolic process IEP Predicted GO
BP GO:0046488 phosphatidylinositol metabolic process IEP Predicted GO
MF GO:0051537 2 iron, 2 sulfur cluster binding IEP Predicted GO
BP GO:0051716 cellular response to stimulus IEP Predicted GO
MF GO:0060589 nucleoside-triphosphatase regulator activity IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0098772 molecular function regulator IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
InterPro domains Description Start Stop
IPR014893 Ku_PK_bind 157 272
No external refs found!