PSME_00009135-RA


Description : (at1g48050 : 87.8) Ku80 and ku70 form the heterodimer complex Ku, required for proper maintenance of the telomeric C strand. Ku regulates the extension of the telomeric G strand. Interacts with WEX, and this interaction stimulates the WEX exonuclease activity. Binds double stranded DNA breaks as a heterodimer with Ku70, involved in non-homologous end joining repair. Mutants are defective in T-DNA integration. Over expression confers increased resistance to DNA damage agents and increased susceptibility to T-DNA transformation.; KU80; FUNCTIONS IN: double-stranded DNA binding, protein binding; INVOLVED IN: in 6 processes; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ku70/Ku80, N-terminal alpha/beta (InterPro:IPR005161), DNA helicase, ATP-dependent, Ku type (InterPro:IPR006164), Spen Paralogue and Orthologue SPOC, C-terminal-like (InterPro:IPR016194), Ku70/Ku80 C-terminal arm (InterPro:IPR005160), Ku, C-terminal (InterPro:IPR014893); Has 786 Blast hits to 750 proteins in 217 species: Archae - 0; Bacteria - 40; Metazoa - 246; Fungi - 345; Plants - 62; Viruses - 0; Other Eukaryotes - 93 (source: NCBI BLink). & (reliability: 175.6) & (original description: no original description)


Gene families : OG_42_0001893 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001893_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00009135-RA
Cluster HCCA clusters: Cluster_97


Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source
BP GO:0000726 non-recombinational repair IEP Predicted GO
MF GO:0004366 glycerol-3-phosphate O-acyltransferase activity IEP Predicted GO
CC GO:0005643 nuclear pore IEP Predicted GO
CC GO:0005956 protein kinase CK2 complex IEP Predicted GO
BP GO:0006302 double-strand break repair IEP Predicted GO
BP GO:0006303 double-strand break repair via nonhomologous end joining IEP Predicted GO
MF GO:0008237 metallopeptidase activity IEP Predicted GO
BP GO:0009719 response to endogenous stimulus IEP Predicted GO
BP GO:0009725 response to hormone IEP Predicted GO
BP GO:0009733 response to auxin IEP Predicted GO
BP GO:0010033 response to organic substance IEP Predicted GO
MF GO:0016874 ligase activity IEP Predicted GO
MF GO:0019207 kinase regulator activity IEP Predicted GO
MF GO:0019887 protein kinase regulator activity IEP Predicted GO
BP GO:0042126 nitrate metabolic process IEP Predicted GO
BP GO:0042128 nitrate assimilation IEP Predicted GO
BP GO:0071941 nitrogen cycle metabolic process IEP Predicted GO
BP GO:2001057 reactive nitrogen species metabolic process IEP Predicted GO
InterPro domains Description Start Stop
IPR005161 Ku_N 64 163
No external refs found!