Description : (at5g63910 : 161.0) Encodes a farnesylcysteine lyase (EC 1.8.3.5) involved in a salvage /detoxification pathway of farnesylcysteine (FC) residues that are liberated during the degradation of prenylated proteins. Because FC is a competitive inhibitor of prenylcysteine methyltransferases involved in the down-regulation of ABA signaling, fcly mutants with elevated FC levels are hypersensitive to ABA. The protein also appears to be glycosylated when translated in vitro in the presence of microsomal membranes and it likely requires FAD for enzymatic activity.; farnesylcysteine lyase (FCLY); FUNCTIONS IN: prenylcysteine oxidase activity; INVOLVED IN: prenylated protein catabolic process, abscisic acid mediated signaling pathway, farnesyl diphosphate metabolic process; LOCATED IN: plasma membrane, vacuole; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Prenylcysteine lyase (InterPro:IPR010795), Prenylcysteine oxidase (InterPro:IPR017046); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 322.0) & (original description: no original description)
Gene families : OG_42_0004385 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004385_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00009195-RA | |
Cluster | HCCA clusters: Cluster_97 |
Type | GO Term | Name | Evidence | Source |
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MF | GO:0016670 | oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor | IEA | InterProScan predictions |
BP | GO:0030328 | prenylcysteine catabolic process | IEA | InterProScan predictions |
BP | GO:0055114 | oxidation-reduction process | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004298 | threonine-type endopeptidase activity | IEP | Predicted GO |
CC | GO:0005839 | proteasome core complex | IEP | Predicted GO |
BP | GO:0005984 | disaccharide metabolic process | IEP | Predicted GO |
BP | GO:0005985 | sucrose metabolic process | IEP | Predicted GO |
BP | GO:0006508 | proteolysis | IEP | Predicted GO |
MF | GO:0008233 | peptidase activity | IEP | Predicted GO |
MF | GO:0008641 | ubiquitin-like modifier activating enzyme activity | IEP | Predicted GO |
MF | GO:0016157 | sucrose synthase activity | IEP | Predicted GO |
MF | GO:0016787 | hydrolase activity | IEP | Predicted GO |
MF | GO:0016877 | ligase activity, forming carbon-sulfur bonds | IEP | Predicted GO |
MF | GO:0016879 | ligase activity, forming carbon-nitrogen bonds | IEP | Predicted GO |
MF | GO:0016881 | acid-amino acid ligase activity | IEP | Predicted GO |
BP | GO:0019725 | cellular homeostasis | IEP | Predicted GO |
CC | GO:0019773 | proteasome core complex, alpha-subunit complex | IEP | Predicted GO |
BP | GO:0032446 | protein modification by small protein conjugation | IEP | Predicted GO |
BP | GO:0042592 | homeostatic process | IEP | Predicted GO |
BP | GO:0045116 | protein neddylation | IEP | Predicted GO |
BP | GO:0045454 | cell redox homeostasis | IEP | Predicted GO |
MF | GO:0070003 | threonine-type peptidase activity | IEP | Predicted GO |
MF | GO:0070011 | peptidase activity, acting on L-amino acid peptides | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR010795 | Prenylcys_lyase | 149 | 231 |
No external refs found! |