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  5. PSME_00009776-RA

PSME_00009776-RA


Description : (at1g63440 : 1097.0) The Arabidopsis P-type ATPase HMA5 is involved in Cu detoxification. hma5 mutant plants exhibit Cu hypersensitivity, which is especially dramatic in roots where HMA5 is mostly expressed.; heavy metal atpase 5 (HMA5); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; INVOLVED IN: detoxification of copper ion, response to copper ion; LOCATED IN: integral to membrane, membrane; EXPRESSED IN: 8 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Heavy metal transport/detoxification protein (InterPro:IPR006121), ATPase, P type, cation/copper-transporter (InterPro:IPR006403), ATPase, P-type, ATPase-associated domain (InterPro:IPR008250), Heavy-metal-associated, conserved site (InterPro:IPR017969), Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (InterPro:IPR001757), ATPase, P-type, heavy metal translocating (InterPro:IPR006416), ATPase, P-type phosphorylation site (InterPro:IPR018303); BEST Arabidopsis thaliana protein match is: copper-exporting ATPase / responsive-to-antagonist 1 / copper-transporting ATPase (RAN1) (TAIR:AT5G44790.1); Has 47061 Blast hits to 34034 proteins in 3459 species: Archae - 1020; Bacteria - 31793; Metazoa - 4958; Fungi - 2589; Plants - 1873; Viruses - 3; Other Eukaryotes - 4825 (source: NCBI BLink). & (q2qmx9|aca1_orysa : 113.0) Calcium-transporting ATPase 1, plasma membrane-type (EC 3.6.3.8) (Ca(2+)-ATPase isoform 1) (Plastid envelope ATPase 1) - Oryza sativa (Rice) & (reliability: 2194.0) & (original description: no original description)


Gene families : OG_42_0000805 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000805_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00009776-RA
Cluster HCCA clusters: Cluster_248

Target Alias Description ECC score Gene Family Method Actions
HORVU2Hr1G097010.8 No alias P1B-type heavy metal cation-transporting ATPase *(HMA) 0.04 Orthogroups_2024-Update
Sobic.010G220600.1 No alias P1B-type heavy metal cation-transporting ATPase *(HMA) 0.06 Orthogroups_2024-Update

Type GO Term Name Evidence Source
BP GO:0030001 metal ion transport IEA InterProScan predictions
MF GO:0046872 metal ion binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0003993 acid phosphatase activity IEP Predicted GO
MF GO:0005506 iron ion binding IEP Predicted GO
CC GO:0005737 cytoplasm IEP Predicted GO
BP GO:0005985 sucrose metabolic process IEP Predicted GO
BP GO:0006020 inositol metabolic process IEP Predicted GO
BP GO:0006066 alcohol metabolic process IEP Predicted GO
MF GO:0016157 sucrose synthase activity IEP Predicted GO
MF GO:0016491 oxidoreductase activity IEP Predicted GO
MF GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen IEP Predicted GO
MF GO:0016758 transferase activity, transferring hexosyl groups IEP Predicted GO
MF GO:0016791 phosphatase activity IEP Predicted GO
MF GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters IEP Predicted GO
MF GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters IEP Predicted GO
MF GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors IEP Predicted GO
BP GO:0019310 inositol catabolic process IEP Predicted GO
BP GO:0019751 polyol metabolic process IEP Predicted GO
MF GO:0033897 ribonuclease T2 activity IEP Predicted GO
MF GO:0042578 phosphoric ester hydrolase activity IEP Predicted GO
BP GO:0044262 cellular carbohydrate metabolic process IEP Predicted GO
BP GO:0044275 cellular carbohydrate catabolic process IEP Predicted GO
BP GO:0044281 small molecule metabolic process IEP Predicted GO
BP GO:0044282 small molecule catabolic process IEP Predicted GO
BP GO:0046164 alcohol catabolic process IEP Predicted GO
BP GO:0046174 polyol catabolic process IEP Predicted GO
MF GO:0046914 transition metal ion binding IEP Predicted GO
MF GO:0050113 inositol oxygenase activity IEP Predicted GO
BP GO:0055114 oxidation-reduction process IEP Predicted GO
BP GO:1901615 organic hydroxy compound metabolic process IEP Predicted GO
BP GO:1901616 organic hydroxy compound catabolic process IEP Predicted GO
InterPro domains Description Start Stop
IPR006121 HMA_dom 169 228
IPR006121 HMA_dom 90 150
IPR006121 HMA_dom 247 303
No external refs found!