PSME_00009849-RA

Description : (at4g30870 : 346.0) Encodes an Arabidopsis homolog of the endonuclease MSU81. T-DNA insertion lines of AtMSU81 have a deficiency in homologous recombination in somatic cells but only after genotoxic stress. Crosses with a hyperrecombinogenic mutant of the AtRecQ4A helicase resulted in synthetic lethality in the double mutant.; MMS AND UV SENSITIVE 81 (MUS81); CONTAINS InterPro DOMAIN/s: ERCC4 domain (InterPro:IPR006166), Helix-hairpin-helix DNA-binding motif, class 1 (InterPro:IPR003583), Restriction endonuclease, type II-like (InterPro:IPR011335); BEST Arabidopsis thaliana protein match is: Restriction endonuclease, type II-like superfamily protein (TAIR:AT5G39770.1); Has 631 Blast hits to 481 proteins in 192 species: Archae - 11; Bacteria - 4; Metazoa - 158; Fungi - 249; Plants - 48; Viruses - 0; Other Eukaryotes - 161 (source: NCBI BLink). & (reliability: 692.0) & (original description: no original description)

Gene families : OG_42_0005044 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0005044_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pseudotsuga release: PSME_00009849-RA
Cluster	HCCA clusters: Cluster_151

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	InterProScan predictions
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004518	nuclease activity	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	IEP	Predicted GO
BP	GO:0006351	transcription, DNA-templated	IEP	Predicted GO
MF	GO:0016779	nucleotidyltransferase activity	IEP	Predicted GO
BP	GO:0032774	RNA biosynthetic process	IEP	Predicted GO
MF	GO:0034062	5'-3' RNA polymerase activity	IEP	Predicted GO
BP	GO:0097659	nucleic acid-templated transcription	IEP	Predicted GO
MF	GO:0097747	RNA polymerase activity	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR006166	ERCC4_domain	264	382

External Links

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PSME_00009849-RA

Expression Profile

Co-expression Networks

Functional Annotation