Description : (at1g75950 : 178.0) SKP1 is core component of the SCF family of E3 ubiquitin ligases and serves to tether the rest of the complex to an F-box protein, which provides specificity in binding to ubiquitin ligase substrate proteins. Predominately expressed from leptotene to pachytene. Negatively regulates recombination. Interacts with P0, a silencing suppressor protein encoded by poleroviruses by means of a conserved minimal F-box motif.; S phase kinase-associated protein 1 (SKP1); FUNCTIONS IN: ubiquitin-protein ligase activity, protein binding; INVOLVED IN: negative regulation of DNA recombination, response to cadmium ion, mitosis, male meiosis, ubiquitin-dependent protein catabolic process; LOCATED IN: in 7 components; EXPRESSED IN: 35 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: E3 ubiquitin ligase, SCF complex, Skp subunit (InterPro:IPR016897), SKP1 component, dimerisation (InterPro:IPR016072), SKP1 component (InterPro:IPR001232), BTB/POZ fold (InterPro:IPR011333), SKP1 component, POZ (InterPro:IPR016073); BEST Arabidopsis thaliana protein match is: E3 ubiquitin ligase SCF complex subunit SKP1/ASK1 family protein (TAIR:AT5G42190.1); Has 1455 Blast hits to 1451 proteins in 268 species: Archae - 0; Bacteria - 0; Metazoa - 552; Fungi - 179; Plants - 538; Viruses - 11; Other Eukaryotes - 175 (source: NCBI BLink). & (reliability: 356.0) & (original description: no original description)
Gene families : OG_42_0000356 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000356_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00010539-RA | |
Cluster | HCCA clusters: Cluster_320 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
Brara.G03391.1 | No alias | ASK-type linker component of SCF E3 ubiquitin ligase complexes | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0006511 | ubiquitin-dependent protein catabolic process | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds | IEP | Predicted GO |
BP | GO:0005975 | carbohydrate metabolic process | IEP | Predicted GO |
BP | GO:0005984 | disaccharide metabolic process | IEP | Predicted GO |
BP | GO:0005985 | sucrose metabolic process | IEP | Predicted GO |
MF | GO:0008173 | RNA methyltransferase activity | IEP | Predicted GO |
MF | GO:0008194 | UDP-glycosyltransferase activity | IEP | Predicted GO |
MF | GO:0008408 | 3'-5' exonuclease activity | IEP | Predicted GO |
MF | GO:0016157 | sucrose synthase activity | IEP | Predicted GO |
MF | GO:0016798 | hydrolase activity, acting on glycosyl bonds | IEP | Predicted GO |
BP | GO:0019725 | cellular homeostasis | IEP | Predicted GO |
MF | GO:0035251 | UDP-glucosyltransferase activity | IEP | Predicted GO |
BP | GO:0042592 | homeostatic process | IEP | Predicted GO |
BP | GO:0045454 | cell redox homeostasis | IEP | Predicted GO |
No external refs found! |