Description : (at1g48050 : 163.0) Ku80 and ku70 form the heterodimer complex Ku, required for proper maintenance of the telomeric C strand. Ku regulates the extension of the telomeric G strand. Interacts with WEX, and this interaction stimulates the WEX exonuclease activity. Binds double stranded DNA breaks as a heterodimer with Ku70, involved in non-homologous end joining repair. Mutants are defective in T-DNA integration. Over expression confers increased resistance to DNA damage agents and increased susceptibility to T-DNA transformation.; KU80; FUNCTIONS IN: double-stranded DNA binding, protein binding; INVOLVED IN: in 6 processes; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ku70/Ku80, N-terminal alpha/beta (InterPro:IPR005161), DNA helicase, ATP-dependent, Ku type (InterPro:IPR006164), Spen Paralogue and Orthologue SPOC, C-terminal-like (InterPro:IPR016194), Ku70/Ku80 C-terminal arm (InterPro:IPR005160), Ku, C-terminal (InterPro:IPR014893); Has 786 Blast hits to 750 proteins in 217 species: Archae - 0; Bacteria - 40; Metazoa - 246; Fungi - 345; Plants - 62; Viruses - 0; Other Eukaryotes - 93 (source: NCBI BLink). & (reliability: 326.0) & (original description: no original description)
Gene families : OG_42_0001893 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001893_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00010641-RA | |
Cluster | HCCA clusters: Cluster_283 |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0016817 | hydrolase activity, acting on acid anhydrides | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0000155 | phosphorelay sensor kinase activity | IEP | Predicted GO |
MF | GO:0003899 | DNA-directed 5'-3' RNA polymerase activity | IEP | Predicted GO |
MF | GO:0004057 | arginyltransferase activity | IEP | Predicted GO |
MF | GO:0004673 | protein histidine kinase activity | IEP | Predicted GO |
BP | GO:0006020 | inositol metabolic process | IEP | Predicted GO |
BP | GO:0006066 | alcohol metabolic process | IEP | Predicted GO |
BP | GO:0006351 | transcription, DNA-templated | IEP | Predicted GO |
BP | GO:0006721 | terpenoid metabolic process | IEP | Predicted GO |
MF | GO:0008661 | 1-deoxy-D-xylulose-5-phosphate synthase activity | IEP | Predicted GO |
BP | GO:0016114 | terpenoid biosynthetic process | IEP | Predicted GO |
BP | GO:0016598 | protein arginylation | IEP | Predicted GO |
MF | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen | IEP | Predicted GO |
MF | GO:0016744 | transferase activity, transferring aldehyde or ketonic groups | IEP | Predicted GO |
MF | GO:0016755 | transferase activity, transferring amino-acyl groups | IEP | Predicted GO |
MF | GO:0016775 | phosphotransferase activity, nitrogenous group as acceptor | IEP | Predicted GO |
MF | GO:0016779 | nucleotidyltransferase activity | IEP | Predicted GO |
MF | GO:0016831 | carboxy-lyase activity | IEP | Predicted GO |
BP | GO:0019310 | inositol catabolic process | IEP | Predicted GO |
BP | GO:0019751 | polyol metabolic process | IEP | Predicted GO |
BP | GO:0032774 | RNA biosynthetic process | IEP | Predicted GO |
MF | GO:0034062 | 5'-3' RNA polymerase activity | IEP | Predicted GO |
BP | GO:0044275 | cellular carbohydrate catabolic process | IEP | Predicted GO |
BP | GO:0046164 | alcohol catabolic process | IEP | Predicted GO |
BP | GO:0046174 | polyol catabolic process | IEP | Predicted GO |
MF | GO:0050113 | inositol oxygenase activity | IEP | Predicted GO |
BP | GO:0097659 | nucleic acid-templated transcription | IEP | Predicted GO |
MF | GO:0097747 | RNA polymerase activity | IEP | Predicted GO |
BP | GO:1901616 | organic hydroxy compound catabolic process | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR014893 | Ku_PK_bind | 105 | 220 |
No external refs found! |