Description : (at5g19400 : 134.0) Encodes SMG7, a protein that possesses an evolutionarily conserved EST1 domain and exhibits strong homology to human SMG6 (EST1A) and SMG7 (EST1C) proteins. SMG7 plays an evolutionarily conserved role in nonsense-mediated RNA decay (NMD). Required for exit from meiosis. Hypomorphic smg7 alleles render mutant plants sterile by causing an unusual cell-cycle arrest in anaphase II that is characterized by delayed chromosome decondensation and aberrant rearrangement of the meiotic spindle. Disruption of SMG7 causes embryonic lethality.; SMG7; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: meiosis, spindle assembly involved in meiosis, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Telomerase activating protein Est1 (InterPro:IPR019458); BEST Arabidopsis thaliana protein match is: Telomerase activating protein Est1 (TAIR:AT1G28260.2). & (reliability: 268.0) & (original description: no original description)
Gene families : OG_42_0003131 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003131_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00010693-RA | |
Cluster | HCCA clusters: Cluster_74 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
PSME_00001085-RA | No alias | (at5g19400 : 141.0) Encodes SMG7, a protein that... | 0.01 | Orthogroups_2024-Update | |
Solyc12g019980 | No alias | Telomerase activating protein Est1 (AHRD V3.3 --* AT5G19400.5) | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004143 | diacylglycerol kinase activity | IEP | Predicted GO |
MF | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds | IEP | Predicted GO |
BP | GO:0007186 | G protein-coupled receptor signaling pathway | IEP | Predicted GO |
BP | GO:0007205 | protein kinase C-activating G protein-coupled receptor signaling pathway | IEP | Predicted GO |
MF | GO:0008964 | phosphoenolpyruvate carboxylase activity | IEP | Predicted GO |
MF | GO:0016798 | hydrolase activity, acting on glycosyl bonds | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR019458 | EST1 | 72 | 162 |
No external refs found! |