PSME_00011088-RA

Description : (at1g08370 : 258.0) Encodes DCP1 involved in mRNA decapping. DCP1 forms a mRNA decapping complex with DCP2 (At5g13570) and VCS (VARICOSE) (At3g13300). However, unlike DCP2, DCP1 itself does not have mRNA decapping activity in vitro. DCP1, DCP2 and VCS colocalize in cytoplasmic loci, which are putative Arabidopsis mRNA processing bodies. Null mutants of DCP1, DCP2, and VCS accumulate capped mRNAs with a reduced degradation rate. These mutants also share a similar lethal phenotype at the seedling cotyledon stage, with disorganized veins, swollen root hairs, and altered epidermal cell morphology. The protein was shown by immunoprecipitation not to interact with DCP2.; decapping 1 (DCP1); CONTAINS InterPro DOMAIN/s: Dcp1-like decapping (InterPro:IPR010334); Has 3561 Blast hits to 2917 proteins in 377 species: Archae - 4; Bacteria - 239; Metazoa - 1310; Fungi - 561; Plants - 741; Viruses - 142; Other Eukaryotes - 564 (source: NCBI BLink). & (reliability: 516.0) & (original description: no original description)

Gene families : OG_42_0001999 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001999_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pseudotsuga release: PSME_00011088-RA
Cluster	HCCA clusters: Cluster_98

Target	Alias	Description	ECC score	Gene Family Method	Actions
LOC_Os11g05650	No alias	mRNA-decapping enzyme, putative, expressed	0.02	Orthogroups_2024-Update
Sopen01g004900	No alias	Dcp1-like decapping family	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
BP	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA	IEA	InterProScan predictions
BP	GO:0000956	nuclear-transcribed mRNA catabolic process	None	Extended
MF	GO:0003674	molecular_function	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006401	RNA catabolic process	None	Extended
BP	GO:0006402	mRNA catabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008047	enzyme activator activity	IEA	InterProScan predictions
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009057	macromolecule catabolic process	None	Extended
BP	GO:0009892	negative regulation of metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010605	negative regulation of macromolecule metabolic process	None	Extended
BP	GO:0010629	negative regulation of gene expression	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
BP	GO:0016071	mRNA metabolic process	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0019439	aromatic compound catabolic process	None	Extended
MF	GO:0030234	enzyme regulator activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034655	nucleobase-containing compound catabolic process	None	Extended
BP	GO:0043085	positive regulation of catalytic activity	IEA	InterProScan predictions
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044093	positive regulation of molecular function	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044248	cellular catabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044265	cellular macromolecule catabolic process	None	Extended
BP	GO:0044270	cellular nitrogen compound catabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0046700	heterocycle catabolic process	None	Extended
BP	GO:0048519	negative regulation of biological process	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050790	regulation of catalytic activity	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0065009	regulation of molecular function	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0098772	molecular function regulator	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901361	organic cyclic compound catabolic process	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000123	histone acetyltransferase complex	IEP	Predicted GO
CC	GO:0000124	SAGA complex	IEP	Predicted GO
MF	GO:0003676	nucleic acid binding	IEP	Predicted GO
MF	GO:0003723	RNA binding	IEP	Predicted GO
MF	GO:0004590	orotidine-5'-phosphate decarboxylase activity	IEP	Predicted GO
MF	GO:0004652	polynucleotide adenylyltransferase activity	IEP	Predicted GO
MF	GO:0005244	voltage-gated ion channel activity	IEP	Predicted GO
MF	GO:0005247	voltage-gated chloride channel activity	IEP	Predicted GO
MF	GO:0005253	anion channel activity	IEP	Predicted GO
MF	GO:0005254	chloride channel activity	IEP	Predicted GO
MF	GO:0005488	binding	IEP	Predicted GO
CC	GO:0005667	transcription factor complex	IEP	Predicted GO
CC	GO:0005669	transcription factor TFIID complex	IEP	Predicted GO
BP	GO:0006206	pyrimidine nucleobase metabolic process	IEP	Predicted GO
BP	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	IEP	Predicted GO
BP	GO:0006352	DNA-templated transcription, initiation	IEP	Predicted GO
BP	GO:0006357	regulation of transcription by RNA polymerase II	IEP	Predicted GO
BP	GO:0006367	transcription initiation from RNA polymerase II promoter	IEP	Predicted GO
BP	GO:0006396	RNA processing	IEP	Predicted GO
BP	GO:0006821	chloride transport	IEP	Predicted GO
BP	GO:0006886	intracellular protein transport	IEP	Predicted GO
BP	GO:0006888	ER to Golgi vesicle-mediated transport	IEP	Predicted GO
BP	GO:0006914	autophagy	IEP	Predicted GO
BP	GO:0008104	protein localization	IEP	Predicted GO
MF	GO:0008270	zinc ion binding	IEP	Predicted GO
MF	GO:0008308	voltage-gated anion channel activity	IEP	Predicted GO
BP	GO:0009112	nucleobase metabolic process	IEP	Predicted GO
BP	GO:0009891	positive regulation of biosynthetic process	IEP	Predicted GO
BP	GO:0009893	positive regulation of metabolic process	IEP	Predicted GO
BP	GO:0010557	positive regulation of macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0010604	positive regulation of macromolecule metabolic process	IEP	Predicted GO
BP	GO:0010628	positive regulation of gene expression	IEP	Predicted GO
BP	GO:0015031	protein transport	IEP	Predicted GO
MF	GO:0015108	chloride transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	IEP	Predicted GO
BP	GO:0015833	peptide transport	IEP	Predicted GO
BP	GO:0016192	vesicle-mediated transport	IEP	Predicted GO
BP	GO:0018130	heterocycle biosynthetic process	IEP	Predicted GO
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Predicted GO
BP	GO:0019856	pyrimidine nucleobase biosynthetic process	IEP	Predicted GO
MF	GO:0022832	voltage-gated channel activity	IEP	Predicted GO
CC	GO:0030117	membrane coat	IEP	Predicted GO
CC	GO:0030118	clathrin coat	IEP	Predicted GO
CC	GO:0030120	vesicle coat	IEP	Predicted GO
CC	GO:0030125	clathrin vesicle coat	IEP	Predicted GO
CC	GO:0030127	COPII vesicle coat	IEP	Predicted GO
CC	GO:0030130	clathrin coat of trans-Golgi network vesicle	IEP	Predicted GO
CC	GO:0030132	clathrin coat of coated pit	IEP	Predicted GO
CC	GO:0031248	protein acetyltransferase complex	IEP	Predicted GO
BP	GO:0031325	positive regulation of cellular metabolic process	IEP	Predicted GO
BP	GO:0031328	positive regulation of cellular biosynthetic process	IEP	Predicted GO
BP	GO:0032774	RNA biosynthetic process	IEP	Predicted GO
BP	GO:0032784	regulation of DNA-templated transcription, elongation	IEP	Predicted GO
BP	GO:0032786	positive regulation of DNA-templated transcription, elongation	IEP	Predicted GO
BP	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter	IEP	Predicted GO
BP	GO:0033036	macromolecule localization	IEP	Predicted GO
BP	GO:0034243	regulation of transcription elongation from RNA polymerase II promoter	IEP	Predicted GO
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0042886	amide transport	IEP	Predicted GO
BP	GO:0043631	RNA polyadenylation	IEP	Predicted GO
CC	GO:0044422	organelle part	IEP	Predicted GO
CC	GO:0044428	nuclear part	IEP	Predicted GO
CC	GO:0044431	Golgi apparatus part	IEP	Predicted GO
CC	GO:0044433	cytoplasmic vesicle part	IEP	Predicted GO
CC	GO:0044446	intracellular organelle part	IEP	Predicted GO
CC	GO:0044451	nucleoplasm part	IEP	Predicted GO
CC	GO:0044798	nuclear transcription factor complex	IEP	Predicted GO
BP	GO:0045184	establishment of protein localization	IEP	Predicted GO
BP	GO:0045893	positive regulation of transcription, DNA-templated	IEP	Predicted GO
BP	GO:0045935	positive regulation of nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0045944	positive regulation of transcription by RNA polymerase II	IEP	Predicted GO
BP	GO:0046112	nucleobase biosynthetic process	IEP	Predicted GO
MF	GO:0046873	metal ion transmembrane transporter activity	IEP	Predicted GO
BP	GO:0046907	intracellular transport	IEP	Predicted GO
BP	GO:0048193	Golgi vesicle transport	IEP	Predicted GO
BP	GO:0048518	positive regulation of biological process	IEP	Predicted GO
BP	GO:0048522	positive regulation of cellular process	IEP	Predicted GO
BP	GO:0051173	positive regulation of nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0051254	positive regulation of RNA metabolic process	IEP	Predicted GO
BP	GO:0051641	cellular localization	IEP	Predicted GO
BP	GO:0051649	establishment of localization in cell	IEP	Predicted GO
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	IEP	Predicted GO
BP	GO:0061919	process utilizing autophagic mechanism	IEP	Predicted GO
CC	GO:0070461	SAGA-type complex	IEP	Predicted GO
MF	GO:0070566	adenylyltransferase activity	IEP	Predicted GO
BP	GO:0071702	organic substance transport	IEP	Predicted GO
BP	GO:0071705	nitrogen compound transport	IEP	Predicted GO
BP	GO:0072527	pyrimidine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	IEP	Predicted GO
CC	GO:0090575	RNA polymerase II transcription factor complex	IEP	Predicted GO
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Predicted GO
CC	GO:1902493	acetyltransferase complex	IEP	Predicted GO
CC	GO:1902494	catalytic complex	IEP	Predicted GO
CC	GO:1902554	serine/threonine protein kinase complex	IEP	Predicted GO
BP	GO:1902680	positive regulation of RNA biosynthetic process	IEP	Predicted GO
CC	GO:1902911	protein kinase complex	IEP	Predicted GO
BP	GO:1903508	positive regulation of nucleic acid-templated transcription	IEP	Predicted GO
CC	GO:1905368	peptidase complex	IEP	Predicted GO
CC	GO:1990234	transferase complex	IEP	Predicted GO
CC	GO:1990316	Atg1/ULK1 kinase complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR010334	Dcp1	17	131

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PSME_00011088-RA

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation