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  5. PSME_00013767-RA

PSME_00013767-RA


Description : (at2g30110 : 372.0) Encodes a ubiquitin-activating enzyme (E1), involved in the first step in conjugating multiple ubiquitins to proteins targeted for degradation. Gene is expressed in most tissues examined. Mutant is able to revert the constitutive defense responses phenotype of snc1, which indicates the gene is involved in defense response. It also indicates that ubiquitination plays a role in plant defense signalling.; ubiquitin-activating enzyme 1 (UBA1); FUNCTIONS IN: ubiquitin-protein ligase activity, ubiquitin activating enzyme activity; INVOLVED IN: response to cadmium ion, response to other organism, protein ubiquitination, ubiquitin-dependent protein catabolic process; LOCATED IN: plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ubiquitin-activating enzyme, E1, active site (InterPro:IPR018074), Ubiquitin-activating enzyme, E1 (InterPro:IPR018075), Ubiquitin-activating enzyme e1, C-terminal (InterPro:IPR018965), Ubiquitin-activating enzyme repeat (InterPro:IPR000127), Ubiquitin-activating enzyme (InterPro:IPR019572), UBA/THIF-type NAD/FAD binding fold (InterPro:IPR000594), Molybdenum cofactor biosynthesis, MoeB (InterPro:IPR009036), NAD(P)-binding domain (InterPro:IPR016040), Ubiquitin-activating enzyme, E1-like (InterPro:IPR000011); BEST Arabidopsis thaliana protein match is: ubiquitin activating enzyme 2 (TAIR:AT5G06460.1); Has 19490 Blast hits to 12603 proteins in 2346 species: Archae - 393; Bacteria - 11015; Metazoa - 2131; Fungi - 1366; Plants - 791; Viruses - 0; Other Eukaryotes - 3794 (source: NCBI BLink). & (p31251|ube12_wheat : 357.0) Ubiquitin-activating enzyme E1 2 - Triticum aestivum (Wheat) & (reliability: 744.0) & (original description: no original description)


Gene families : OG_42_0123486 (Orthogroups_2024-Update) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00013767-RA
Cluster HCCA clusters: Cluster_227


Type GO Term Name Evidence Source
MF GO:0008641 ubiquitin-like modifier activating enzyme activity IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0004672 protein kinase activity IEP Predicted GO
MF GO:0004866 endopeptidase inhibitor activity IEP Predicted GO
MF GO:0004869 cysteine-type endopeptidase inhibitor activity IEP Predicted GO
MF GO:0005543 phospholipid binding IEP Predicted GO
BP GO:0005991 trehalose metabolic process IEP Predicted GO
BP GO:0005992 trehalose biosynthetic process IEP Predicted GO
BP GO:0006464 cellular protein modification process IEP Predicted GO
BP GO:0006468 protein phosphorylation IEP Predicted GO
BP GO:0006793 phosphorus metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
MF GO:0008289 lipid binding IEP Predicted GO
BP GO:0009312 oligosaccharide biosynthetic process IEP Predicted GO
BP GO:0016192 vesicle-mediated transport IEP Predicted GO
MF GO:0016301 kinase activity IEP Predicted GO
BP GO:0016310 phosphorylation IEP Predicted GO
MF GO:0016772 transferase activity, transferring phosphorus-containing groups IEP Predicted GO
MF GO:0016773 phosphotransferase activity, alcohol group as acceptor IEP Predicted GO
BP GO:0030001 metal ion transport IEP Predicted GO
MF GO:0030414 peptidase inhibitor activity IEP Predicted GO
BP GO:0036211 protein modification process IEP Predicted GO
BP GO:0043412 macromolecule modification IEP Predicted GO
BP GO:0044267 cellular protein metabolic process IEP Predicted GO
BP GO:0046351 disaccharide biosynthetic process IEP Predicted GO
MF GO:0051087 chaperone binding IEP Predicted GO
MF GO:0061134 peptidase regulator activity IEP Predicted GO
MF GO:0061135 endopeptidase regulator activity IEP Predicted GO
MF GO:0140096 catalytic activity, acting on a protein IEP Predicted GO
InterPro domains Description Start Stop
IPR000594 ThiF_NAD_FAD-bd 255 303
IPR032420 E1_4HB 149 208
IPR019572 UBA_E1_Cys 431 511
No external refs found!